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NOD1 Promotes Antiviral Signaling by Binding Viral RNA and Regulating the Interaction of MDA5 and MAVS 期刊论文
JOURNAL OF IMMUNOLOGY, 2020, 卷号: 204, 期号: 8, 页码: 2216-2231
Authors:  Wu, Xiao Man;  Zhang, Jie;  Li, Peng Wei;  Hu, Yi Wei;  Cao, Lu;  Ouyang, Songying;  Bi, Yong Hong;  Nie, Pin;  Chang, Ming Xian
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Histone H2A cooperates with RIP2 to induce the expression of antibacterial genes and MHC related genes 期刊论文
DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY, 2019, 卷号: 101, 期号: 1, 页码: 11
Authors:  Wu, Xiao Man;  Cao, Lu;  Nie, Pin;  Chang, Ming Xian
Adobe PDF(3214Kb)  |  Favorite  |  View/Download:48/0  |  Submit date:2019/11/28
Zebrafish histone H2A  RIP2  Bacterial infection  Antibacterial genes  MHC-Related genes  
Transcriptomic characterization of adult zebrafish infected with Streptococcus agalactiae 期刊论文
FISH & SHELLFISH IMMUNOLOGY, 2019, 卷号: 94, 期号: 1, 页码: 355-372
Authors:  Wu, Xiao Man;  Cao, Lu;  Hu, Yi Wei;  Chang, Ming Xian
Adobe PDF(7433Kb)  |  Favorite  |  View/Download:26/0  |  Submit date:2020/04/07
Zebrafish  RNA-Seq  Intestine  Skin  Immune response  Streptococcus agalactiae XQ-1  
The negative regulation of piscine CD44c in viral and bacterial infection 期刊论文
DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY, 2019, 卷号: 96, 页码: 135-143
Authors:  Cao, Lu;  Wu, Xiao Man;  Nie, Pin;  Chang, Ming Xian
Favorite  |  View/Download:74/0  |  Submit date:2019/06/10
Zebrafish CD44  Viral infection  Bacterial infection  Inflammatory cytokines  Antiviral genes  MHC genes  Antibacterial molecules  Negative regulation  
The discrepancy function of NLRC5 isoforms in antiviral and antibacterial immune responses 期刊论文
DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY, 2018, 卷号: 84, 期号: 1, 页码: 153-163
Authors:  Cao, Lu;  Wu, Xiao Man;  Hu, Yi Wei;  Xue, Na Na;  Nie, Pin;  Chang, Ming Xian
Adobe PDF(3905Kb)  |  Favorite  |  View/Download:38/3  |  Submit date:2019/07/03
Zebrafish  NLRC5 isoforms  Viral infection  Bacterial infection  TLRs signaling  NF-kappa B signaling  
RIP2 Is a Critical Regulator for NLRs Signaling and MHC Antigen Presentation but Not for MAPK and PI3K/Akt Pathways 期刊论文
FRONTIERS IN IMMUNOLOGY, 2018, 卷号: 9, 期号: 1, 页码: 18
Authors:  Wu, Xiao Man;  Chen, Wen Qin;  Hu, Yi Wei;  Cao, Lu;  Nie, Pin;  Chang, Ming Xian
Adobe PDF(11296Kb)  |  Favorite  |  View/Download:40/3  |  Submit date:2019/07/03
RIP2 deficiency  larval survival  transcriptome analysis  signaling pathways  NLRs signaling  MHC antigen presentation  
TanK-Binding Kinase 1 (TBK1) Isoforms Negatively Regulate Type I Interferon Induction by Inhibiting TBK1-IRF3 Interaction and IRF3 Phosphorylation 期刊论文
FRONTIERS IN IMMUNOLOGY, 2018, 卷号: 9, 期号: 1, 页码: 17
Authors:  Hu, Yi Wei;  Zhang, Jie;  Wu, Xiao Man;  Cao, Lu;  Nie, Pin;  Chang, Ming Xian
Adobe PDF(6693Kb)  |  Favorite  |  View/Download:46/3  |  Submit date:2019/07/03
alternative splicing  spring viremia of carp virus  TANK-binding kinase 1 spliced isoforms  TANK-binding kinase 1  IRF3  type I interferon signaling  immune homeostasis  
一种转录因子的核酸、蛋白质及其应用 专利
专利类型: 发明专利, 专利号: 一种转录因子的核酸、蛋白质及其应用,
Inventors:  昌鸣先;  曹璐;  武小曼
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Role of zebrafish NLRC5 in antiviral response and transcriptional regulation of MHC related genes 期刊论文
DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY, 2017, 卷号: 68, 期号: 1, 页码: 58-68
Authors:  Wu, Xiao Man;  Hu, Yi Wei;  Xue, Na Na;  Ren, Shi Si;  Chen, Shan Nan;  Nie, Pin;  Chang, Ming Xian
Adobe PDF(2354Kb)  |  Favorite  |  View/Download:34/3  |  Submit date:2019/09/29
Zebrafish  NLRC5  SVCV infection  Antiviral activity  MHC class II transactivator