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Generation and characterization of gsu alpha:EGFP transgenic zebrafish for evaluating endocrine-disrupting effects 期刊论文
TOXICOLOGY AND APPLIED PHARMACOLOGY, 2014, 卷号: 278, 期号: 1, 页码: 78-84
Authors:  Cheng, Xiaoxia;  Chen, Xiaowen;  Jin, Xia;  He, Jiangyan;  Yin, Zhan;  Yin, Z (reprint author), Chinese Acad Sci, Inst Hydrobiol, Key Lab Aquat Biodivers & Conservat, Wuhan, Hubei, Peoples R China.
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Gsu Alpha Promoter  Pituitary Hormone  Transgenic Zebrafish  Gsu Alpha Expression  Endocrine Disrupting  
Sulforaphane inhibits CYP1A1 activity and promotes genotoxicity induced by 2,3,7,8-tetrachlorodibenzo-p-dioxin in vitro 期刊论文
TOXICOLOGY AND APPLIED PHARMACOLOGY, 2013, 卷号: 269, 期号: 3, 页码: 226-232
Authors:  Yang, Fangxing;  Zhuang, Shulin;  Zhang, Chao;  Dai, Heping;  Liu, Weiping;  Yang, FX (reprint author), Zhejiang Univ, Coll Environm & Resource Sci, 388 Yuhangtang Rd, Hangzhou 310058, Peoples R China.
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Sulforaphane  2,3,7,8-tetrachlorodibenzo-p-dioxin  Cyp1a1 Activity  H4iie Cell  Genotoxicity  Yeast  
Use of TSH beta:EGFP transgenic zebrafish as a rapid in vivo model for assessing thyroid-disrupting chemicals 期刊论文
TOXICOLOGY AND APPLIED PHARMACOLOGY, 2012, 卷号: 262, 期号: 2, 页码: 149-155
Authors:  Ji, Cheng;  Jin, Xia;  He, Jiangyan;  Yin, Zhan;  Yin, Z (reprint author), Chinese Acad Sci, Key Lab Aquat Biodivers & Conservat, Inst Hydrobiol, Wuhan, Hubei, Peoples R China.
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Thyroid-stimulating Hormone Subunit-beta  Hypothalamic-pituitary-thyroid  Endocrine Disrupting  Transgenic Reporter Fish  Assessment Model  
Sulforaphane prevents microcystin-LR-induced oxidative damage and apoptosis in BALB/c mice 期刊论文
TOXICOLOGY AND APPLIED PHARMACOLOGY, 2011, 卷号: 255, 期号: 1, 页码: 9-17
Authors:  Sun, Xiaoyun;  Mi, Lixin;  Liu, Jin;  Song, Lirong;  Chung, Fung-Lung;  Gan, Nanqin;  Song, LR (reprint author), CAS, Inst Hydrobiol, State Key Lab Freshwater Ecol & Biotechnol, Donghu Nanlu 7, Wuhan 430072, Peoples R China;  lrsong@ihb.ac.cn;  gannq@ihb.ac.cn
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Microcystin-lr (Mc-lr)  Sulforaphane (Sfn)  Nf-e2-related Factor 2 (Nrf2)  Apoptosis  Reactive Oxygen Species (Ros)  
In vivo alternative assessment of the chemicals that interfere with anterior pituitary POMC expression and interrenal steroidogenesis in POMC: EGFP transgenic zebrafish 期刊论文
TOXICOLOGY AND APPLIED PHARMACOLOGY, 2010, 卷号: 248, 期号: 3, 页码: 217-225
Authors:  Sun, Lingli;  Xu, Wei;  He, Jiangyan;  Yin, Zhan;  Yin, Z, Chinese Acad Sci, Inst Hydrobiol, Wuhan 430072, Hubei, Peoples R China
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Endocrine Disruption  Zebrafish  Pomc:Egfp Transgenic Line  Interrenal Development  
Sulforaphane protects Microcystin-LR-induced toxicity through activation of the Nrf2-mediated defensive response 期刊论文
TOXICOLOGY AND APPLIED PHARMACOLOGY, 2010, 卷号: 247, 期号: 2, 页码: 129-137
Authors:  Gan, Nanqin;  Mi, Lixin;  Sun, Xiaoyun;  Dai, Guofei;  Chung, Fung-Lung;  Song, Lirong;  Song, LR, CAS, Inst Hydrobiol, State Key Lab Freshwater Ecol & Biotechnol, Beijing, Peoples R China
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Microcystin-lr (Mc-lr)  Sulforaphane (Sfn)  Nf-e2-related Factor 2 (Nrf2)  Phase Ii Enzymes  Glutathione (Gsh)  Chemoprevention  
Chronic exposure to environmental levels of tribromophenol impairs zebrafish reproduction 期刊论文
TOXICOLOGY AND APPLIED PHARMACOLOGY, 2010, 卷号: 243, 期号: 1, 页码: 87-95
Authors:  Deng, Jun;  Liu, Chunsheng;  Yu, Liqin;  Zhou, Bingsheng;  Zhou, BS, Chinese Acad Sci, Inst Hydrobiol, State Key Lab Freshwater Ecol & Biotechnol, Wuhan 430072, Peoples R China
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Tribromophenol  Endocrine Disruption  Sex Hormones  Steroidogenic Genes  Reproduction  Zebrafish  
Effects of fluorotelomer alcohol 8/2 FTOH on steroidogenesis in H295R cells: Targeting the cAMP signalling cascade 期刊论文
TOXICOLOGY AND APPLIED PHARMACOLOGY, 2010, 卷号: 247, 期号: 3, 页码: 222-228
Authors:  Liu, Chunsheng;  Zhang, Xiaowei;  Chang, Hong;  Jones, Paul;  Wiseman, Steve;  Naile, Jonathan;  Hecker, Markus;  Giesy, John P.;  Zhou, Bingsheng;  Zhang, XW, Nanjing Univ, Sch Environm, Nanjing 210089, Peoples R China
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Steroid Hormone Production  Gene Expression  Adenylate Cyclase  Ftoh  
Effects of adrenergic agents on the expression of zebrafish (Danio rerio) vitellogenin Ao1 期刊论文
TOXICOLOGY AND APPLIED PHARMACOLOGY, 2009, 卷号: 238, 期号: 1, 页码: 20-26
Authors:  Yin, Naida;  Jin, Xia;  He, Jiangyan;  Yin, Zhan;  Yin, Z, Chinese Acad Sci, Inst Hydrobiol, Key Lab Biodivers & Conservat Aquat Organisms, Wuhan 430072, Hubei, Peoples R China
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Zebrafish  Vtgao1  Adrenergic Agents  Heart  Liver  
Developmental toxicity and alteration of gene expression in zebrafish embryos exposed to PFOS 期刊论文
TOXICOLOGY AND APPLIED PHARMACOLOGY, 2008, 卷号: 230, 期号: 1, 页码: 23-32
Authors:  Shi, Xiongjie;  Du, Yongbing;  Lam, Paul K. S.;  Wu, Rudolf S. S.;  Zhou, Bingsheng;  Zhou, BS, Chinese Acad Sci, Inst Hydrobiol, State Key Lab Freshwater Ecol & Biotechnol, Wuhan 430072, Peoples R China
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Pfos  Developmental Toxicity  Gene Expression  Apoptosis  Embryo  Zebrafish