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Systematic genome editing of the genes on zebrafish Chromosome 1 by CRISPR/Cas9 期刊论文
GENOME RESEARCH, 2020, 卷号: 30, 期号: 1, 页码: 118-126
Authors:  Sun, Yonghua;  Zhang, Bo;  Luo, Lingfei;  Shi, De-Li;  Wang, Han;  Cui, Zongbin;  Huang, Honghui;  Cao, Ying;  Shu, Xiaodong;  Zhang, Wenqing;  Zhou, Jianfeng;  Li, Yun;  Du, Jiulin;  Zhao, Qingshun;  Chen, Jun;  Zhong, Hanbing;  Zhong, Tao P.;  Li, Li;  Xiong, Jing-Wei;  Peng, Jinrong;  Xiao, Wuhan;  Zhang, Jian;  Yao, Jihua;  Yin, Zhan;  Mo, Xianming;  Peng, Gang;  Zhu, Jun;  Chen, Yan;  Zhou, Yong;  Liu, Dong;  Pan, Weijun;  Zhang, Yiyue;  Ruan, Hua;  Liu, Feng;  Zhu, Zuoyan;  Meng, Anming;  Sun, Yonghua;  Pan, Luyuan;  Wang, Houpeng;  Xie, Weixun;  He, Mudan;  Ye, Ding;  Li, Kuoyu;  Xiong, Feng;  Liu, Liyue;  Li, Linglu;  Zhang, Yun;  Zhang, Bo;  Liu, Da;  Cheng, Zhenchao;  Hu, Yingying;  Wu, Qian;  Luo, Zhou;  Zhang, Yutian;  Wu, Yingdan;  Li, Wenyuan;  Luo, Lingfei;  Ma, Jianlong;  Mo, Dashuang;  Cai, Pengcheng;  Chen, Jinzi;  Sun, Junhui;  Zhou, Yang;  Wu, Chuan;  Ni, Rui;  Shi, De-Li;  Shao, Ming;  Zhang, Yan-Jun;  Feng, Li-Jun;  Cheng, Xiao-Ning;  Li, Ji-Tong;  Xing, Yan-Yi;  Zhang, Yan;  Meng, Ya-Ping;  Yu, Bei-Bei;  Wang, Han;  Huang, Jian;  Zhang, Shuqing;  Ji, Cheng;  Tan, Yicheng;  Wang, Jingjing;  Zhang, Fanmiao;  Wang, Mingyong;  Huang, Guodong;  Zhong, Zhaomin;  Zhang, Wei;  Cui, Zongbin;  Long, Yong;  Song, Guili;  Li, Xiaohui;  Li, Xixi;  Chen, Kai;  Ren, Jing;  Yan, Junjun;  Li, Qing;  Huang, Honghui;  Ruan, Hua;  Zhu, Shicheng;  Chen, Xuejiao;  Pan, Jingjing;  Jiang, Faming;  Chen, Jiehui;  Huang, Chao;  Dong, Guoping;  Yi, Xiaogui;  Cao, Ying;  Hu, Ruikun;  Huang, Weilai;  Liu, Jiangfang;  Hong WangXiao;  Shu, Dong;  Xia, Jianhong;  Zhao, Shaoyang;  Wang, Pengtao;  Wu, Xiuhua;  Zhang, Wenqing;  Zhang, Yiyue;  Xu, Mengchang;  Liu, Wei;  Huang, Zhibing;  Lin, Qing;  Wu, Mei;  Zhou, Jianfeng;  Sheng, Aibo;  Tang, Peipei;  Gong, Xiaoxia;  Mou, Wei;  Zu, Congcong;  Li, Yun;  Lu, Ling;  Liu, Yunzhang;  Rong, Xiaozhi;  Chen, Jianyang;  Du, Jiulin;  Bu, Jiwen;  Du, Xufei;  Liu, Tingting;  Gu, Shanye;  Zhao, Qingshun;  Dong, Zhangji;  Dong, Xiaohua;  Cao, Shasha;  Yue, Yunyun;  Gu, Chun;  Liu, Meijing;  Chen, Jun;  Gong, Hongjian;  Zhong, Hanbing;  Yang, Xuanjun;  Chen, Jiahao;  Xu, Qiushi;  Zhong, Tao P.;  Jin, Daqin;  She, Peilu;  Sun, Jianjian;  Lai, Kaa Seng;  Li, Li;  Zhang, Yu;  Shi, Yanyan;  Zhao, Fangying;  Xiong, Jing-Wei;  Pang, Meijun;  Gao, Lu;  Lei, Lei;  Peng, Jinrong;  Lo, Jane;  Xiao, Wuhan;  Cai, Xiaolian;  Ouyang, Gang;  Zhang, Jian;  Ma, Weirui;  Miao, Liyun;  Yao, Jihua;  Hu, Yu;  Yin, Zhan;  Mo, Xianming;  Li, Xue;  Peng, Gang;  Zhang, Cuizhen;  Wang, Fenghua;  Zhu, Jun;  Yang, Ruimeng;  Yuan, Hao;  Chen, Yan;  Pan, Yi;  Zhou, Yong;  Liu, Dong;  Zhao, Feng;  Pan, Weijun;  Liu, Feng;  Ding, Yanyan;  Xue, Yuanyuan;  Wang, Lu;  Zhang, Yifan;  Ma, Dongyuan;  Lu, Xinyan;  Gao, Shuai;  Xia, Jun;  Zhu, Zuoyan;  Meng, Anming;  Liu, Xingfeng;  Qiu, Juhui;  Gong, Bo;  Chen, Luxi;  Xiong, Cong;  Yao, Likun;  Xing, Cencan;  Wang, Yixia;  Shen, Weimin;  Sun, Jiawei
Favorite  |  View/Download:212/0  |  Submit date:2020/05/13
斑马鱼ints12的CRISPR/Cas9敲除及其对UsnRNA剪接的调控 期刊论文
水生生物学报, 2019, 期号: 01, 页码: 1-8
Authors:  黄思雨;  何牡丹;  王厚鹏;  孙永华
Adobe PDF(1422Kb)  |  Favorite  |  View/Download:57/4  |  Submit date:2019/07/11
ints12  CRISPR/Cas9  UsnRNA  mRNA加工  
团头鲂nanos3基因的克隆鉴定 期刊论文
水生生物学报, 2019, 期号: 03, 页码: 457-464
Authors:  朱林;  王厚鹏;  朱作言;  孙永华;  叶鼎
Adobe PDF(1337Kb)  |  Favorite  |  View/Download:64/7  |  Submit date:2019/07/09
Nanos3  团头鲂  原始生殖细胞  斑马鱼  
Deficiency of lrp4 in zebrafish and human LRP4 mutation induce aberrant activation of Jagged-Notch signaling in fin and limb development 期刊论文
CELLULAR AND MOLECULAR LIFE SCIENCES, 2019, 卷号: 76, 期号: 1, 页码: 163-178
Authors:  Tian, Jing;  Shao, Jinhui;  Liu, Cong;  Hou, Hsin-Yu;  Chou, Chih-Wei;  Shboul, Mohammad;  Li, Guo-Qing;  El-Khateeb, Mohammad;  Samarah, Omar Q.;  Kou, Yao;  Chen, Yu-Hsuan;  Chen, Mei-Jen;  Lyu, Zhaojie;  Chen, Wei-Leng;  Chen, Yu-Fu;  Sun, Yong-Hua;  Liu, Yi-Wen
Adobe PDF(9971Kb)  |  Favorite  |  View/Download:57/8  |  Submit date:2019/07/01
Skeletogenesis  Bone disorders  Pronephros  Morphant  Phenocopy  EGF-like domain  wt1b  HES1  
国家斑马鱼资源中心的资源、技术和服务建设 期刊论文
遗传, 2018, 期号: 08, 页码: 683-692
Authors:  熊凤;  谢训卫;  潘鲁媛;  李阔宇;  柳力月;  张昀;  李玲璐;  孙永华
Adobe PDF(1875Kb)  |  Favorite  |  View/Download:74/2  |  Submit date:2019/07/11
斑马鱼  国家中心  资源  技术  服务  
加强海洋微塑料的生态和健康危害研究 提升风险管控能力 期刊论文
中国科学院院刊, 2018, 期号: 10, 页码: 1003-1011
Authors:  徐向荣;  孙承君;  季荣;  王菊英;  吴辰熙;  施华宏;  骆永明
Adobe PDF(1995Kb)  |  Favorite  |  View/Download:48/3  |  Submit date:2019/07/11
微塑料污染  海洋环境  生态和健康危害  风险管控  
Genome editing opens a new era for physiological study and directional breeding of fishes 期刊论文
SCIENCE BULLETIN, 2017, 卷号: 62, 期号: 3, 页码: 157-158
Authors:  Sun, Yong-Hua
Adobe PDF(3731Kb)  |  Favorite  |  View/Download:29/3  |  Submit date:2019/09/29
一种用于原始生殖细胞靶向突变的转基因载体及制备方法和用途 专利
专利类型: 发明专利, 专利号: 一种用于原始生殖细胞靶向突变的转基因载体及制备方法和用途, 申请日期: 2016-01-27, 公开日期: 2016-01-27
Inventors:  熊凤;  孙永华;  叶鼎;  朱作言
Unknown(704Kb)  |  Favorite  |  View/Download:32/7  |  Submit date:2019/11/27
Efficient ligase 3-dependent microhomology-mediated end joining repair of DNA double-strand breaks in zebrafish embryos 期刊论文
MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS, 2015, 卷号: 780, 页码: 86-96
Authors:  He, Mu-Dan;  Zhang, Feng-Hua;  Wang, Hua-Lin;  Wang, Hou-Peng;  Zhu, Zuo-Yan;  Sun, Yong-Hua
Favorite  |  View/Download:21/0  |  Submit date:2015/11/24
Double-strand Breaks Repair  Transcription Activator-like Effector Nuclease (Talen)  Crispr (Clustered Regularly Interspaced Short Palindromic Repeats)/cas9  Microhomology-mediated End Joining (Mmej)  Ligase 3  Ligase 4  
Transcriptional Activity and DNA Methylation Dynamics of the Gal4/UAS System in Zebrafish 期刊论文
MARINE BIOTECHNOLOGY, 2015, 卷号: 17, 期号: 5, 页码: 593-603
Authors:  Pang, Shao-Chen;  Wang, Hou-Peng;  Zhu, Zuo-Yan;  Sun, Yong-Hua
Favorite  |  View/Download:25/0  |  Submit date:2015/10/08
Gal4/uas  Transcriptional Activity  Transcriptional Silencing  Dna Methylation  Zebrafish