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Quantitative analysis of glutathione and cysteine S-conjugates of microcystin-LR in the liver, kidney and muscle of common carp (Cyprinus carpio) in Lake Taihu 期刊论文
JOURNAL OF WATER AND HEALTH, 2017, 卷号: 15, 期号: 2, 页码: 300-307
Authors:  Wu, Laiyan;  Wang, Songbo;  Tao, Min;  Xie, Ping;  Chen, Jun
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common carp  kidney  liver  MC-LR-Cys  MC-LR-GSH  
Rapid conversion and reversible conjugation of glutathione detoxification of microcystins in bighead carp (Aristich-thys nobilis) 期刊论文
AQUATIC TOXICOLOGY, 2014, 卷号: 147, 页码: 18-25
Authors:  Li, Wei;  Chen, Jun;  Xie, Ping;  He, Jun;  Guo, Xiaochun;  Tuo, Xun;  Zhang, Wei;  Wu, Laiyan;  Chen, J (reprint author), Chinese Acad Sci, Inst Hydrobiol, State Key Lab Freshwater Ecol & Biotechnol China, Donghu Expt Stn Lake Ecosyst, Donghu South Rd 7, Wuhan 430072, Peoples R China.
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Biotransformation And Detoxification  Mechanisms  Mc-rr-gsh/cys  Gsh Pathway  Bighead Carp  
Why mammals more susceptible to the hepatotoxic microcystins than fish: evidences from plasma and albumin protein binding through equilibrium dialysis 期刊论文
ECOTOXICOLOGY, 2013, 卷号: 22, 期号: 6, 页码: 1012-1019
Authors:  Zhang, Wei;  Liang, Gaodao;  Wu, Laiyan;  Tuo, Xun;  Wang, Wenjing;  Chen, Jun;  Xie, Ping;  Xie, P (reprint author), Chinese Acad Sci, Donghu Expt Stn Lake Ecosyst, State Key Lab Freshwater Ecol & Biotechnol China, Inst Hydrobiol, Wuhan 430072, Peoples R China.
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Microcystins  Plasma Protein  Albumin  Equilibrium Dialysis  
Preliminary Study of the Distribution and Accumulation of GSH/Cys Metabolites of Hepatotoxic Microcystins-RR in Common Carp from a Lake with Protracted Cyanobacterial Bloom (Lake Taihu, China) 期刊论文
BULLETIN OF ENVIRONMENTAL CONTAMINATION AND TOXICOLOGY, 2013, 卷号: 90, 期号: 3, 页码: 382-386
Authors:  Wu, Laiyan;  Wang, Qing;  Tao, Min;  Chen, Jun;  Ma, Zhimei;  Xie, Ping;  Xie, P (reprint author), Chinese Acad Sci, Inst Hydrobiol, State Key Lab Freshwater Ecol & Biotechnol China, Donghu Expt Stn Lake Ecosyst, Donghu South Rd 7th, Wuhan 430072, Peoples R China.
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Mc-rr-gsh  Mc-rr-cys  Common Carp  Lc-ms  Risk Assessment  
一种微囊藻毒素的提取和纯化方法 专利
专利类型: 发明, 专利号: 一种微囊藻毒素的提取和纯化方法, 申请日期: 2011-01-26, 公开日期: 2011-01-26
Inventors:  谢平;  王文静;  国晓春;  梁高道;  吴来燕;  张伟;  戴明;  张大文
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Metabolic Response to Oral Microcystin-LR Exposure in the Rat by NMR-Based Metabonomic Study 期刊论文
JOURNAL OF PROTEOME RESEARCH, 2012, 卷号: 11, 期号: 12, 页码: 5934-5946
Authors:  He, Jun;  Chen, Jun;  Wu, Laiyan;  Li, Guangyu;  Xie, Ping;  Chen, J (reprint author), Chinese Acad Sci, Inst Hydrobiol, State Key Lab Freshwater Ecol & Biotechnol China, Donghu Expt Stn Lake Ecosyst, Donghu S Rd 7, Wuhan 430072, Peoples R China.
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Microcystin-lr  Metabonomics  Nmr  Glutathione  Choline  Nutrient Absorption  
Quantitatively evaluating detoxification of the hepatotoxic microcystins through the glutathione and cysteine pathway in the cyanobacteria-eating bighead carp 期刊论文
AQUATIC TOXICOLOGY, 2012, 卷号: 116, 期号: -, 页码: 61-68
Authors:  He, Jun;  Chen, Jun;  Xie, Ping;  Zhang, Dawen;  Li, Guangyu;  Wu, Laiyan;  Zhang, Wei;  Guo, Xiaochun;  Li, Shangchun;  Chen, J (reprint author), Chinese Acad Sci, Inst Hydrobiol, Donghu Expt Stn Lake Ecosyst, State Key Lab Freshwater Ecol & Biotechnol China, Donghu S Rd 7, Wuhan 430072, Peoples R China.
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Quantification  Mclr-gsh/cys  Mcrr-gsh/cys  Bighead Carp  
Use of a Generalized Additive Model to Investigate Key Abiotic Factors Affecting Microcystin Cellular Quotas in Heavy Bloom Areas of Lake Taihu 期刊论文
PLOS ONE, 2012, 卷号: 7, 期号: 2, 页码: e32020
Authors:  Tao, Min;  Xie, Ping;  Chen, Jun;  Qin, Boqiang;  Zhang, Dawen;  Niu, Yuan;  Zhang, Meng;  Wang, Qing;  Wu, Laiyan;  Tao, M (reprint author), Chinese Acad Sci, Inst Hydrobiol, State Key Lab Freshwater Ecol & Biotechnol China, Donghu Expt Stn Lake Ecosyst, Wuhan, Peoples R China.
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Cyanobacterium Microcystis  Toxic Cyanobacteria  Inorganic Carbon  Meiliang Bay  Hepatotoxin Production  Environmental-factors  Aeruginosa Pcc7806  Growth  China  Lr  
微囊藻毒素及其GSH/Cys 代谢物的测定方法研究及应用 学位论文
, 北京: 中国科学院水生生物研究所, 2011
Authors:  吴来燕
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Protein expression profiling in the zebrafish (Danio rerio) embryos exposed to the microcystin-LR 期刊论文
PROTEOMICS, 2011, 卷号: 11, 期号: 10, 页码: 2003-2018
Authors:  Li, Guangyu;  Chen, Jun;  Xie, Ping;  Jiang, Yan;  Wu, Laiyan;  Zhang, Xuezhen;  Xie, P, Chinese Acad Sci, Donghu Expt Stn Lake Ecosyst, State Key Lab Freshwater Ecol & Biotechnol China, Inst Hydrobiol, Donghu S Rd 7, Wuhan 430072, Peoples R China;  xieping@ihb.ac.cn
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Animal Proteomics  Developmental Toxicity  Gene Expression  Microcystin-leucine-arginine  Zebrafish