Health risks associated with genetic alterations in internal clock system by external factors
Khan, Suliman1,2,3; Nabi, Ghulam1,3; Yao, Lunguang2; Siddique, Rabeea4,5; Sajjad, Wasim3,6; Kumar, Sunjeet1; Duan, Pengfei2; Hou, Hongwei1
2018
Source PublicationINTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES
ISSN1449-2288
Volume14Issue:7Pages:791-798
AbstractThe circadian system maintains the main aspects of physiological and behavioral processes. Both circadian rhythm and sleep impact an organism's health through interaction with environmental factors. Variations in external factors influence the functionality of clock genes and disrupt 24-hour rhythmic cycle. The disrupted circadian rhythm and disregulated sleep affect an organism's health, thereby causing several disorders including cancer, depression and cardiac disorders. Considering the role of clock genes and environmental factors, extensive investigation is required focusing on pathways involved in development of life-threatening disorders. This review identifies the major risks and associated factors related with disruption in circadian system and sleep.
SubtypeReview
KeywordCircadian System Sleep Health Risks Clock Genes
DOI10.7150/ijbs.23744
WOS HeadingsScience & Technology ; Life Sciences & Biomedicine
Indexed BySCI
Funding OrganizationScientific research and service platform fund of Henan Province(2016151) ; Scientific research and service platform fund of Henan Province(2016151) ; fund of scientific and technological innovation team of water ecological security for Water Source Region of Mid-line of South-to-North Diversion Project of Henan Province(17454) ; fund of scientific and technological innovation team of water ecological security for Water Source Region of Mid-line of South-to-North Diversion Project of Henan Province(17454) ; CAS-TWAS president's fellowship ; CAS-TWAS president's fellowship ; Scientific research and service platform fund of Henan Province(2016151) ; Scientific research and service platform fund of Henan Province(2016151) ; fund of scientific and technological innovation team of water ecological security for Water Source Region of Mid-line of South-to-North Diversion Project of Henan Province(17454) ; fund of scientific and technological innovation team of water ecological security for Water Source Region of Mid-line of South-to-North Diversion Project of Henan Province(17454) ; CAS-TWAS president's fellowship ; CAS-TWAS president's fellowship
Language英语
WOS Research AreaBiochemistry & Molecular Biology ; Life Sciences & Biomedicine - Other Topics
WOS SubjectBiochemistry & Molecular Biology ; Biology
WOS KeywordGLUCOSE-METABOLISM IMPLICATIONS ; SLEEP-PHASE SYNDROME ; CIRCADIAN CLOCK ; SHIFT-WORK ; THERAPEUTIC IMPLICATIONS ; MOLECULAR-COMPONENTS ; LIGHT EXPOSURE ; FOOD-INTAKE ; JET-LAG ; DISORDER
WOS IDWOS:000433261800010
Funding OrganizationScientific research and service platform fund of Henan Province(2016151) ; Scientific research and service platform fund of Henan Province(2016151) ; fund of scientific and technological innovation team of water ecological security for Water Source Region of Mid-line of South-to-North Diversion Project of Henan Province(17454) ; fund of scientific and technological innovation team of water ecological security for Water Source Region of Mid-line of South-to-North Diversion Project of Henan Province(17454) ; CAS-TWAS president's fellowship ; CAS-TWAS president's fellowship ; Scientific research and service platform fund of Henan Province(2016151) ; Scientific research and service platform fund of Henan Province(2016151) ; fund of scientific and technological innovation team of water ecological security for Water Source Region of Mid-line of South-to-North Diversion Project of Henan Province(17454) ; fund of scientific and technological innovation team of water ecological security for Water Source Region of Mid-line of South-to-North Diversion Project of Henan Province(17454) ; CAS-TWAS president's fellowship ; CAS-TWAS president's fellowship
Citation statistics
Document Type期刊论文
Identifierhttp://ir.ihb.ac.cn/handle/342005/50893
Collection藻类生物学及应用研究中心_水生生物分子与细胞生物学研究中心
Affiliation1.Chinese Acad Sci, Inst Hydrobiol, Key Lab Aquat Biodivers & Conservat, Wuhan 430072, Hubei, Peoples R China
2.Nanyang Normal Univ, Henan Key Lab Ecol Secur Water Source Reg Mid Lin, Collaborat Innovat Ctr Water Secur Water Source R, Nanyang, Henan, Peoples R China
3.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
4.Huazhong Univ Sci & Technol, Adv Biomat & Tissue Engn Ctr, Wuhan 430074, Hubei, Peoples R China
5.Huazhong Univ Sci & Technol, Dept Biomed Engn, Wuhan 430074, Hubei, Peoples R China
6.Chinese Acad Sci, Inst Geol & Geophys, Key Lab Petr Resources, Gansu Prov Key Lab Petr Resources Res, Lanzhou 730000, Gansu, Peoples R China
Recommended Citation
GB/T 7714
Khan, Suliman,Nabi, Ghulam,Yao, Lunguang,et al. Health risks associated with genetic alterations in internal clock system by external factors[J]. INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES,2018,14(7):791-798.
APA Khan, Suliman.,Nabi, Ghulam.,Yao, Lunguang.,Siddique, Rabeea.,Sajjad, Wasim.,...&Hou, Hongwei.(2018).Health risks associated with genetic alterations in internal clock system by external factors.INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES,14(7),791-798.
MLA Khan, Suliman,et al."Health risks associated with genetic alterations in internal clock system by external factors".INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES 14.7(2018):791-798.
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