Shiftwork-Mediated Disruptions of Circadian Rhythms and Sleep Homeostasis Cause Serious Health Problems
Khan, Suliman1; Duan, Pengfei2; Yao, Lunguang2; Hou, Hongwei1
2018
Source PublicationINTERNATIONAL JOURNAL OF GENOMICS
ISSN2314-436X
AbstractShiftwork became common during the last few decades with the growing demands of human life. Despite the social inactivity and irregularity in habits, working in continuous irregular shifts causes serious health issues including sleep disorders, psychiatric disorders, cancer, and metabolic disorders. These health problems arise due to the disruption in circadian clock system, which is associated with alterations in genetic expressions. Alteration in clock controlling genes further affects genes linked with disorders including major depression disorder, bipolar disorder, phase delay and phase advance sleep syndromes, breast cancer, and colon cancer. A diverse research work is needed focusing on broad spectrum changes caused by jet lag in brain and neuronal system. This review is an attempt to motivate the researchers to conduct advanced studies in this area to identify the risk factors and mechanisms. Its goal is extended to make the shift workers aware about the risks associated with shiftwork.
SubtypeReview
DOI10.1155/2018/8576890
WOS HeadingsScience & Technology ; Life Sciences & Biomedicine
Indexed BySCI ; SSCI
Funding OrganizationNational Natural Science Foundation of China(31372381) ; National Natural Science Foundation of China(31372381) ; Henan Scientific and Technological Innovation Team Fund(17454) ; Henan Scientific and Technological Innovation Team Fund(17454) ; Chinese Academy of Science and The World Academy of Science (CAS-TWAS) scholarship program ; Chinese Academy of Science and The World Academy of Science (CAS-TWAS) scholarship program ; National Natural Science Foundation of China(31372381) ; National Natural Science Foundation of China(31372381) ; Henan Scientific and Technological Innovation Team Fund(17454) ; Henan Scientific and Technological Innovation Team Fund(17454) ; Chinese Academy of Science and The World Academy of Science (CAS-TWAS) scholarship program ; Chinese Academy of Science and The World Academy of Science (CAS-TWAS) scholarship program
Language英语
WOS Research AreaBiochemistry & Molecular Biology ; Biotechnology & Applied Microbiology ; Genetics & Heredity
WOS SubjectBiochemistry & Molecular Biology ; Biotechnology & Applied Microbiology ; Genetics & Heredity
WOS KeywordMAJOR DEPRESSIVE DISORDER ; CHRONIC JET-LAG ; METABOLIC SYNDROME ; RISK-FACTOR ; THERAPEUTIC IMPLICATIONS ; PSYCHIATRIC-DISORDERS ; PREVENTS OBESITY ; MENTAL-HEALTH ; CANCER-RISK ; WEIGHT-GAIN
WOS IDWOS:000424458200001
Funding OrganizationNational Natural Science Foundation of China(31372381) ; National Natural Science Foundation of China(31372381) ; Henan Scientific and Technological Innovation Team Fund(17454) ; Henan Scientific and Technological Innovation Team Fund(17454) ; Chinese Academy of Science and The World Academy of Science (CAS-TWAS) scholarship program ; Chinese Academy of Science and The World Academy of Science (CAS-TWAS) scholarship program ; National Natural Science Foundation of China(31372381) ; National Natural Science Foundation of China(31372381) ; Henan Scientific and Technological Innovation Team Fund(17454) ; Henan Scientific and Technological Innovation Team Fund(17454) ; Chinese Academy of Science and The World Academy of Science (CAS-TWAS) scholarship program ; Chinese Academy of Science and The World Academy of Science (CAS-TWAS) scholarship program
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Document Type期刊论文
Identifierhttp://ir.ihb.ac.cn/handle/342005/50679
Collection藻类生物学及应用研究中心_水生生物分子与细胞生物学研究中心
Affiliation1.Chinese Acad Sci, Inst Hydrobiol, Key Lab Aquat Biodivers & Conservat, Wuhan 430072, Hubei, Peoples R China
2.Nanyang Normal Univ, Coll Agr Engn, Collaborat Innovat Ctr Water & Secur Water Source, South To North Divers Project, Nanyang, Henan, Peoples R China
Recommended Citation
GB/T 7714
Khan, Suliman,Duan, Pengfei,Yao, Lunguang,et al. Shiftwork-Mediated Disruptions of Circadian Rhythms and Sleep Homeostasis Cause Serious Health Problems[J]. INTERNATIONAL JOURNAL OF GENOMICS,2018.
APA Khan, Suliman,Duan, Pengfei,Yao, Lunguang,&Hou, Hongwei.(2018).Shiftwork-Mediated Disruptions of Circadian Rhythms and Sleep Homeostasis Cause Serious Health Problems.INTERNATIONAL JOURNAL OF GENOMICS.
MLA Khan, Suliman,et al."Shiftwork-Mediated Disruptions of Circadian Rhythms and Sleep Homeostasis Cause Serious Health Problems".INTERNATIONAL JOURNAL OF GENOMICS (2018).
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