IHB OpenIR  > 专利
工程化细鞘丝藻及其生产GLA的应用
Rights Holder中国科学院水生生物研究所
Date Available2020
Subtype发明专利
Abstract本发明涉及细鞘丝藻在生产GLA上的应用;还涉及一种工程化的细鞘丝藻,所述细鞘丝藻中,desB基因被敲除,并且转入desD基因过表达盒;还涉及一种生产GLA的方法,包括培养上述细鞘丝藻,并使所述细鞘丝藻生产GLA的步骤;还涉及一种desB基因,编码的蛋白质序列如SEQ ID NO:3所示。本发明的工程化细鞘丝藻能够开放式大规模培养。在开放式半连续培养中,藻株具有良好的生物质产率和GLA产率(平均生物质产率为19.1±4.9g·m‑2·d‑1,平均GLA产率为0.35±0.07g·m‑2·d‑1)。此外,本发明的工程化细鞘丝藻不生产ALA,省去了分离GLA与ALA工序,降低了纯化难度和成本。 机器翻译
Application Date2020
Status在审
Application NumberCN202010786190.X
Open (Notice) NumberCN112048460A
IPC Classification NumberC12N1/21(2006.01) ; C12N15/53(2006.01) ; C12N9/02(2006.01) ; C12P7/64(2006.01) ; C12R1/01(2006.01)
Document Type专利
Identifierhttp://ir.ihb.ac.cn/handle/342005/39531
Collection专利
Recommended Citation
GB/T 7714
. 工程化细鞘丝藻及其生产GLA的应用.
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