| The circadian clock and darkness control natural competence in cyanobacteria | |
| Taton, Arnaud1; Erikson, Christian1,3; Yang, Yiling2,4; Rubin, Benjamin E.1,3; Rifkin, Scott A.1; Golden, James W.1; Golden, Susan S.1,2 | |
| Corresponding Author | Golden, Susan S.(sgolden@ucsd.edu) |
| 2020-04-03 | |
| Source Publication | NATURE COMMUNICATIONS
 |
| ISSN | 2041-1723 |
| Volume | 11Issue:1Pages:11 |
| Abstract | The cyanobacterium Synechococcus elongatus is a model organism for the study of circadian rhythms. It is naturally competent for transformation-that is, it takes up DNA from the environment, but the underlying mechanisms are unclear. Here, we use a genome-wide screen to identify genes required for natural transformation in S. elongatus, including genes encoding a conserved Type IV pilus, genes known to be associated with competence in other bacteria, and others. Pilus biogenesis occurs daily in the morning, while natural transformation is maximal when the onset of darkness coincides with the dusk circadian peak. Thus, the competence state in cyanobacteria is regulated by the circadian clock and can adapt to seasonal changes of day length. |
| DOI | 10.1038/s41467-020-15384-9 |
| Funding Organization | National Institute of General Medical Sciences of the National Institutes of Health ; National Institute of General Medical Sciences of the National Institutes of Health ; National Institute of General Medical Sciences of the National Institutes of Health ; National Institute of General Medical Sciences of the National Institutes of Health ; National Science Foundation ; National Science Foundation ; National Science Foundation ; National Science Foundation ; National Institute of General Medical Sciences of the National Institutes of Health ; National Institute of General Medical Sciences of the National Institutes of Health ; National Institute of General Medical Sciences of the National Institutes of Health ; National Institute of General Medical Sciences of the National Institutes of Health ; National Science Foundation ; National Science Foundation ; National Science Foundation ; National Science Foundation ; National Institute of General Medical Sciences of the National Institutes of Health ; National Institute of General Medical Sciences of the National Institutes of Health ; National Institute of General Medical Sciences of the National Institutes of Health ; National Institute of General Medical Sciences of the National Institutes of Health ; National Science Foundation ; National Science Foundation ; National Science Foundation ; National Science Foundation ; National Institute of General Medical Sciences of the National Institutes of Health ; National Institute of General Medical Sciences of the National Institutes of Health ; National Institute of General Medical Sciences of the National Institutes of Health ; National Institute of General Medical Sciences of the National Institutes of Health ; National Science Foundation ; National Science Foundation ; National Science Foundation ; National Science Foundation |
| Indexed By | SCI ; SCI |
| Language | 英语 |
| Funding Project | National Institute of General Medical Sciences of the National Institutes of Health[R35GM118290] ; National Institute of General Medical Sciences of the National Institutes of Health[R01GM118815] ; National Science Foundation[IOS-1754894] |
| WOS Research Area | Science & Technology - Other Topics |
| WOS Subject | Multidisciplinary Sciences |
| WOS ID | WOS:000564274500005 |
| WOS Keyword | GENE-EXPRESSION ; SIGMA-FACTOR ; CELL-DIVISION ; DNA-UPTAKE ; TRANSFORMATION ; PROTEIN ; TIME ; RHYTHMS ; OSCILLATIONS ; MECHANISMS |
| Publisher | NATURE PUBLISHING GROUP |
| Funding Organization | National Institute of General Medical Sciences of the National Institutes of Health ; National Institute of General Medical Sciences of the National Institutes of Health ; National Institute of General Medical Sciences of the National Institutes of Health ; National Institute of General Medical Sciences of the National Institutes of Health ; National Science Foundation ; National Science Foundation ; National Science Foundation ; National Science Foundation ; National Institute of General Medical Sciences of the National Institutes of Health ; National Institute of General Medical Sciences of the National Institutes of Health ; National Institute of General Medical Sciences of the National Institutes of Health ; National Institute of General Medical Sciences of the National Institutes of Health ; National Science Foundation ; National Science Foundation ; National Science Foundation ; National Science Foundation ; National Institute of General Medical Sciences of the National Institutes of Health ; National Institute of General Medical Sciences of the National Institutes of Health ; National Institute of General Medical Sciences of the National Institutes of Health ; National Institute of General Medical Sciences of the National Institutes of Health ; National Science Foundation ; National Science Foundation ; National Science Foundation ; National Science Foundation ; National Institute of General Medical Sciences of the National Institutes of Health ; National Institute of General Medical Sciences of the National Institutes of Health ; National Institute of General Medical Sciences of the National Institutes of Health ; National Institute of General Medical Sciences of the National Institutes of Health ; National Science Foundation ; National Science Foundation ; National Science Foundation ; National Science Foundation |
| Citation statistics | |
| Document Type | 期刊论文 |
| Identifier | http://ir.ihb.ac.cn/handle/342005/38666 |
| Collection | 其他_期刊论文 |
| Corresponding Author | Golden, Susan S. |
| Affiliation | 1.Univ Calif San Diego, Div Biol Sci, La Jolla, CA 92093 USA 2.Univ Calif San Diego, Ctr Circadian Biol, La Jolla, CA 92093 USA 3.Univ Calif Berkeley, Dept Mol & Cell Biol, Berkeley, CA 94720 USA 4.Chinese Acad Sci, Inst Hydrobiol, Wuhan, Hubei, Peoples R China |
| Recommended Citation GB/T 7714 | Taton, Arnaud,Erikson, Christian,Yang, Yiling,et al. The circadian clock and darkness control natural competence in cyanobacteria[J]. NATURE COMMUNICATIONS,2020,11(1):11. |
| APA | Taton, Arnaud.,Erikson, Christian.,Yang, Yiling.,Rubin, Benjamin E..,Rifkin, Scott A..,...&Golden, Susan S..(2020).The circadian clock and darkness control natural competence in cyanobacteria.NATURE COMMUNICATIONS,11(1),11. |
| MLA | Taton, Arnaud,et al."The circadian clock and darkness control natural competence in cyanobacteria".NATURE COMMUNICATIONS 11.1(2020):11. |
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