IHB OpenIR  > 藻类生物学及应用研究中心  > 期刊论文
Cyclic adenosine monophosphate signal pathway is involved in regulation of triacylglycerol biosynthesis following nitrogen deprivation in Chlamydomonas reinhardtii
Miao Rongli1,2; Huang Kaiyao1
2019-10-21
Source PublicationJOURNAL OF OCEANOLOGY AND LIMNOLOGY
ISSN2096-5508
Issue1Pages:12
Abstract

The unicellular green alga, Chlamydomonas reinhardtii is a model organism for studying various biological processes, such as photosynthesis, flagellar motility, and lipid metabolism. To find some novel genes regulating the lipid metabolism under various stress conditions, the paromomycin resistance gene aphVIII was transferred into the genome of C. reinhardtii to establish a mutant library. Two genes mutated in two of the TAG-reduced mutants (Cre06.g278111 in M2 mutant, Cre06.g278110 in M6 mutants) were neighboring in the genome, and their expression levels were down-regulated in their corresponding mutants in parallel with their reduced TAG levels following N deprivation. The proteins encoded by these two genes (KCN11 by Cre06.g278111, ACYC3 by Cre06.g278110) contained a conversed cyclic mononucleotide phosphate (cNMP) binding protein and an adenylate domain, respectively. Since cNMP binding protein and adenylate domain have been known as important components of cyclic adenosine monophosphate (cAMP) signaling pathway, suggesting that these two genes might affect cellular TAG biosynthesis through cAMP signal pathway.

KeywordChlamydomonas reinhardtii mutant lipid droplet (LD) triacylglycerol (TAG) cyclic adenosine monophosphate (cAMP)
DOI10.1007/s00343-019-8345-0
Indexed BySCI
Language英语
WOS Research AreaMarine & Freshwater Biology ; Oceanography
WOS SubjectLimnology ; Oceanography
WOS IDWOS:000491816200006
WOS KeywordLIPID DROPLET PROTEIN ; LEUCINE-RICH REPEAT ; ADIPOSE-TISSUE ; GENE ; ACCUMULATION ; EXPRESSION ; TRANSFORMATION ; TRANSCRIPTION ; BIOGENESIS ; RESISTANCE
PublisherSCIENCE PRESS
Citation statistics
Document Type期刊论文
Identifierhttp://ir.ihb.ac.cn/handle/342005/35326
Collection藻类生物学及应用研究中心_期刊论文
Corresponding AuthorMiao Rongli
Affiliation1.Chinese Acad Sci, Inst Hydrobiol, Key Lab Algal Biol, Wuhan 430072, Hubei, Peoples R China
2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
Recommended Citation
GB/T 7714
Miao Rongli,Huang Kaiyao. Cyclic adenosine monophosphate signal pathway is involved in regulation of triacylglycerol biosynthesis following nitrogen deprivation in Chlamydomonas reinhardtii[J]. JOURNAL OF OCEANOLOGY AND LIMNOLOGY,2019(1):12.
APA Miao Rongli,&Huang Kaiyao.(2019).Cyclic adenosine monophosphate signal pathway is involved in regulation of triacylglycerol biosynthesis following nitrogen deprivation in Chlamydomonas reinhardtii.JOURNAL OF OCEANOLOGY AND LIMNOLOGY(1),12.
MLA Miao Rongli,et al."Cyclic adenosine monophosphate signal pathway is involved in regulation of triacylglycerol biosynthesis following nitrogen deprivation in Chlamydomonas reinhardtii".JOURNAL OF OCEANOLOGY AND LIMNOLOGY .1(2019):12.
Files in This Item:
File Name/Size DocType Version Access License
Miao-Huang2020_Artic(968KB)期刊论文作者接受稿开放获取CC BY-NC-SAView Application Full Text
Related Services
Recommend this item
Bookmark
Usage statistics
Export to Endnote
Google Scholar
Similar articles in Google Scholar
[Miao Rongli]'s Articles
[Huang Kaiyao]'s Articles
Baidu academic
Similar articles in Baidu academic
[Miao Rongli]'s Articles
[Huang Kaiyao]'s Articles
Bing Scholar
Similar articles in Bing Scholar
[Miao Rongli]'s Articles
[Huang Kaiyao]'s Articles
Terms of Use
No data!
Social Bookmark/Share
File name: Miao-Huang2020_Article_CyclicAdenosineMonophosphateSi.pdf
Format: Adobe PDF
All comments (0)
No comment.
 

Items in the repository are protected by copyright, with all rights reserved, unless otherwise indicated.