IHB OpenIR  > 水环境工程研究中心  > 期刊论文
Perfluorobutanesulfonate Exposure Skews Sex Ratio in Fish and Transgenerationally Impairs Reproduction.
Chen, Lianguo; Lam, James C.W.; Hu, Chenyan; Tsui, Mirabelle M.P.; Lam, Paul K.S.; Zhou, Bingsheng
2019-07-16
Source PublicationEnvironmental Science & Technology
ISSN0013-936X
Volume53Issue:14Pages:8389-8397
AbstractPerfluorobutanesulfonate (PFBS) is increasingly polluting aquatic environments due to worldwide manufacturing and application. However, toxicological knowledge regarding PFBS exposure remains scarce. Here, we showed that PFBS life-cycle exposure at environmentally realistic concentrations (0, 1.0, 2.9, and 9.5 [mu]g/L) skewed the sex ratio in fish toward male dominance, while reproductive functions of female fish were greatly impaired, as characterized by extremely small ovaries, blocked oocyte development, and decreased egg production. Endocrine disruption through the hypothalamus-pituitary-gonad axis was induced by PFBS exposure, showing antiestrogenic activity in females but estrogenic activity in males. PFBS was found to gradually accumulate in F0 adults during continuous exposure but can be rapidly eliminated when depurated in clean water. Parental exposure also transferred PFBS pollutant to F1 offspring eggs. Although no trace of PFBS was detected in F1 adults and F2 eggs, adverse effects from parental exposure persisted in F1 and F2 offspring. These transgenerational effects implicate PFBS as an ongoing threat to the fitness and sustainability of fish populations. The dramatic impairment of fish reproduction highlights the urgency of re-evaluations of the ecological and evolutionary consequences of PFBS exposure.
Indexed BySCI ; SCI
Language英语
WOS Research AreaZoology ; Physiology ; Endocrinology & Metabolism ; Reproductive Biology ; Developmental Biology ; Genetics & Heredity ; Environmental Sciences & Ecology
WOS SubjectZOOLOGY ; PHYSIOLOGY ; ENDOCRINOLOGY METABOLISM ; REPRODUCTIVE BIOLOGY ; DEVELOPMENTAL BIOLOGY ; GENETICS HEREDITY ; ECOLOGY ; ENVIRONMENTAL SCIENCES
WOS IDWOS:ZOOR15512082122
Citation statistics
Document Type期刊论文
Identifierhttp://ir.ihb.ac.cn/handle/342005/35254
Collection水环境工程研究中心_期刊论文
AffiliationChinese Acad Sci, Inst Hydrobiol, Wuhan, Hubei, 430072, China
Recommended Citation
GB/T 7714
Chen, Lianguo,Lam, James C.W.,Hu, Chenyan,et al. Perfluorobutanesulfonate Exposure Skews Sex Ratio in Fish and Transgenerationally Impairs Reproduction.[J]. Environmental Science & Technology,2019,53(14):8389-8397.
APA Chen, Lianguo,Lam, James C.W.,Hu, Chenyan,Tsui, Mirabelle M.P.,Lam, Paul K.S.,&Zhou, Bingsheng.(2019).Perfluorobutanesulfonate Exposure Skews Sex Ratio in Fish and Transgenerationally Impairs Reproduction..Environmental Science & Technology,53(14),8389-8397.
MLA Chen, Lianguo,et al."Perfluorobutanesulfonate Exposure Skews Sex Ratio in Fish and Transgenerationally Impairs Reproduction.".Environmental Science & Technology 53.14(2019):8389-8397.
Files in This Item:
There are no files associated with this item.
Related Services
Recommend this item
Bookmark
Usage statistics
Export to Endnote
Google Scholar
Similar articles in Google Scholar
[Chen, Lianguo]'s Articles
[Lam, James C.W.]'s Articles
[Hu, Chenyan]'s Articles
Baidu academic
Similar articles in Baidu academic
[Chen, Lianguo]'s Articles
[Lam, James C.W.]'s Articles
[Hu, Chenyan]'s Articles
Bing Scholar
Similar articles in Bing Scholar
[Chen, Lianguo]'s Articles
[Lam, James C.W.]'s Articles
[Hu, Chenyan]'s Articles
Terms of Use
No data!
Social Bookmark/Share
All comments (0)
No comment.
 

Items in the repository are protected by copyright, with all rights reserved, unless otherwise indicated.