Characterization, expression analysis and localization pattern of toll-like receptor 1 (tlr1) and toll-like receptor 2 (tlr2) genes in grass carp Ctenopharyngodon idella | |
He, L. B.1; Wang, H.1,2; Luo, L. F.1,2; Jiang, S. H.1,3; Liu, L. Y.1; Li, Y. M.1; Huang, R.1; Liao, L. J.1; Zhu, Z. Y.1; Wang, Y. P.1 | |
2016-08-01 | |
Source Publication | JOURNAL OF FISH BIOLOGY
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ISSN | 0022-1112 |
Volume | 89Issue:2Pages:1434-1440 |
Abstract | In this study, the toll-like receptor 1 ( tlr1) and toll-like receptor 2 ( tlr2) genes of grass carp Ctenopharyngodon idella were cloned and characterized. tlr1 and tlr2 were found to be highly expressed in immune system organs such as spleen, middle kidney and heart kidney. The expression level of tlr1 and tlr2 was found to be up-regulated at the later stage of viral challenge process. Moreover, subcellular localization indicated that Tlr1 and Tlr2 shared similar localization pattern and both of them may locate in the plasma membrane of transfected cells. (C) 2016 The Fisheries Society of the British Isles |
Keyword | grass carp Ctenopharyngodon idellus grass carp reovirus immune response toll-like receptor 1 toll-like receptor 2 |
DOI | 10.1111/jfb.12997 |
Indexed By | SCI |
Language | 英语 |
WOS Research Area | Fisheries ; Marine & Freshwater Biology |
WOS Subject | Fisheries ; Marine & Freshwater Biology |
WOS ID | WOS:000384309300019 |
WOS Keyword | LARGE YELLOW CROAKER ; MOLECULAR CHARACTERIZATION ; TELEOST FISH ; BONY FISH ; EVOLUTION ; FAMILY ; RECOGNITION ; PUFFERFISH ; ACTIVATION ; INFECTION |
Publisher | WILEY-BLACKWELL |
Citation statistics | |
Document Type | 期刊论文 |
Identifier | http://ir.ihb.ac.cn/handle/342005/34696 |
Collection | 鱼类生物学及渔业生物技术研究中心_期刊论文 |
Corresponding Author | Wang, Y. P. |
Affiliation | 1.Chinese Acad Sci, Inst Hydrobiol, State Key Lab Freshwater Ecol & Biotechnol, Wuhan 430072, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 3.Kim Il Song Univ, Dept Zool, Coll Life Sci, Pyongyang, North Korea |
Recommended Citation GB/T 7714 | He, L. B.,Wang, H.,Luo, L. F.,et al. Characterization, expression analysis and localization pattern of toll-like receptor 1 (tlr1) and toll-like receptor 2 (tlr2) genes in grass carp Ctenopharyngodon idella[J]. JOURNAL OF FISH BIOLOGY,2016,89(2):1434-1440. |
APA | He, L. B..,Wang, H..,Luo, L. F..,Jiang, S. H..,Liu, L. Y..,...&Wang, Y. P..(2016).Characterization, expression analysis and localization pattern of toll-like receptor 1 (tlr1) and toll-like receptor 2 (tlr2) genes in grass carp Ctenopharyngodon idella.JOURNAL OF FISH BIOLOGY,89(2),1434-1440. |
MLA | He, L. B.,et al."Characterization, expression analysis and localization pattern of toll-like receptor 1 (tlr1) and toll-like receptor 2 (tlr2) genes in grass carp Ctenopharyngodon idella".JOURNAL OF FISH BIOLOGY 89.2(2016):1434-1440. |
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