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一种草鱼抗呼肠孤病毒口服重组芽孢疫苗及其制备方法
宁德刚; 张磊; 费倩; 韦瑶
2017-09-01
Rights Holder中国科学院水生生物研究所
Date Available2017-09-01
Country中国
Subtype发明专利
Abstract

本发明涉及一种草鱼抗呼肠孤病毒口服重组枯草芽孢杆菌芽孢疫苗的制备方法。该疫苗是用草鱼颗粒饲料包被表面展示草鱼呼肠孤病毒免疫保护性抗原的重组枯草芽孢杆菌芽孢而制得;所述芽孢是具有萌发缺陷、无抗生素抗性基因标记的芽孢。本发明的方法包括构建萌发缺陷、无抗生素抗性基因标记和表面展示草鱼呼肠孤病毒免疫保护性抗原的重组枯草芽孢杆菌芽孢,制备草鱼颗粒饲料包被重组芽孢的抗呼肠孤病毒口服重组芽孢疫苗,用于呼肠孤病毒引起的草鱼出血病的防治。

Application Date2017-05-15
Language中文
Application NumberCN201710339270.9
Document Type专利
Identifierhttp://ir.ihb.ac.cn/handle/342005/34278
Collection中科院水生所知识产出(2009年前)
Recommended Citation
GB/T 7714
宁德刚,张磊,费倩,等. 一种草鱼抗呼肠孤病毒口服重组芽孢疫苗及其制备方法[P]. 2017-09-01.
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