IHB OpenIR  > 鱼类生物学及渔业生物技术研究中心  > 期刊论文
Sequential, Divergent, and Cooperative Requirements of Foxl2a and Foxl2b in Ovary Development and Maintenance of Zebrafish
Yang, Yan-Jing1,2; Wang, Yang1; Li, Zhi1; Zhou, Li1; Gui, Jian-Fang1
2017-04-01
Source PublicationGENETICS
ISSN0016-6731
Volume205Issue:4Pages:1551-1572
Abstract

Foxl2 is essential for mammalian ovary maintenance. Although sexually dimorphic expression of foxl2 was observed in many teleosts, its role and regulative mechanism in fish remained largely unclear. In this study, we first identified two transcript variants of foxl2a and its homologous gene foxl2b in zebrafish, and revealed their specific expression in follicular layer cells in a sequential and divergent fashion during ovary differentiation, maturation, and maintenance. Then, homozygous foxl2a mutants ( foxl2a(-/-)) and foxl2b mutants ( foxl2b(-/-)) were constructed and detailed comparisons, such as sex ratio, gonadal histological structure, transcriptome profiling, and dynamic expression of gonadal development-related genes, were carried out. Initial ovarian differentiation and oocyte development occur normally both in foxl2a(-/-) and foxl2b(-/-) mutants, but foxl2a and foxl2b disruptions result in premature ovarian failure and partial sex reversal, respectively, in adult females. In foxl2a(-/-) female mutants, sox9a-amh/cyp19a1a signaling was upregulated at 150 days postfertilization ( dpf) and subsequently oocyte apoptosis was triggered after 180 dpf. In contrast, dmrt1 expression was greater at 105 dpf and increased several 100-fold in foxl2b(-/-) mutated ovaries at 270 dpf, along with other testis-related genes. Finally, homozygous foxl2a(-/-)/foxl2b(-/-) double mutants were constructed in which complete sex reversal occurs early and testis-differentiation genes robustly increase at 60 dpf. Given mutual compensation between foxl2a and foxl2b in foxl2b(-/-) and foxl2a(-/-) mutants, we proposed a model in which foxl2a and foxl2b cooperate to regulate zebrafish ovary development and maintenance, with foxl2b potentially having a dominant role in preventing the ovary from differentiating as testis, as compared to foxl2a.

KeywordFoxl2a Foxl2b premature ovarian failure sex reversal TALEN
DOI10.1534/genetics.116.199133
Funding OrganizationStrategic Priority Research Program of the Chinese Academy of Sciences ; Strategic Priority Research Program of the Chinese Academy of Sciences ; Strategic Priority Research Program of the Chinese Academy of Sciences ; Strategic Priority Research Program of the Chinese Academy of Sciences ; Strategic Priority Research Program of the Chinese Academy of Sciences ; Strategic Priority Research Program of the Chinese Academy of Sciences ; Strategic Priority Research Program of the Chinese Academy of Sciences ; Strategic Priority Research Program of the Chinese Academy of Sciences ; Autonomous Project of the State Key Laboratory of Freshwater Ecology and Biotechnology ; Autonomous Project of the State Key Laboratory of Freshwater Ecology and Biotechnology ; Autonomous Project of the State Key Laboratory of Freshwater Ecology and Biotechnology ; Autonomous Project of the State Key Laboratory of Freshwater Ecology and Biotechnology ; Autonomous Project of the State Key Laboratory of Freshwater Ecology and Biotechnology ; Autonomous Project of the State Key Laboratory of Freshwater Ecology and Biotechnology ; Autonomous Project of the State Key Laboratory of Freshwater Ecology and Biotechnology ; Autonomous Project of the State Key Laboratory of Freshwater Ecology and Biotechnology ; Autonomous Project of the Institute of Hydrobiology, Chinese Academy of Sciences ; Autonomous Project of the Institute of Hydrobiology, Chinese Academy of Sciences ; Autonomous Project of the Institute of Hydrobiology, Chinese Academy of Sciences ; Autonomous Project of the Institute of Hydrobiology, Chinese Academy of Sciences ; Autonomous Project of the Institute of Hydrobiology, Chinese Academy of Sciences ; Autonomous Project of the Institute of Hydrobiology, Chinese Academy of Sciences ; Autonomous Project of the Institute of Hydrobiology, Chinese Academy of Sciences ; Autonomous Project of the Institute of Hydrobiology, Chinese Academy of Sciences ; Strategic Priority Research Program of the Chinese Academy of Sciences ; Strategic Priority Research Program of the Chinese Academy of Sciences ; Strategic Priority Research Program of the Chinese Academy of Sciences ; Strategic Priority Research Program of the Chinese Academy of Sciences ; Strategic Priority Research Program of the Chinese Academy of Sciences ; Strategic Priority Research Program of the Chinese Academy of Sciences ; Strategic Priority Research Program of the Chinese Academy of Sciences ; Strategic Priority Research Program of the Chinese Academy of Sciences ; Autonomous Project of the State Key Laboratory of Freshwater Ecology and Biotechnology ; Autonomous Project of the State Key Laboratory of Freshwater Ecology and Biotechnology ; Autonomous Project of the State Key Laboratory of Freshwater Ecology and Biotechnology ; Autonomous Project of the State Key Laboratory of Freshwater Ecology and Biotechnology ; Autonomous Project of the State Key Laboratory of Freshwater Ecology and Biotechnology ; Autonomous Project of the State Key Laboratory of Freshwater Ecology and Biotechnology ; Autonomous Project of the State Key Laboratory of Freshwater Ecology and Biotechnology ; Autonomous Project of the State Key Laboratory of Freshwater Ecology and Biotechnology ; Autonomous Project of the Institute of Hydrobiology, Chinese Academy of Sciences ; Autonomous Project of the Institute of Hydrobiology, Chinese Academy of Sciences ; Autonomous Project of the Institute of Hydrobiology, Chinese Academy of Sciences ; Autonomous Project of the Institute of Hydrobiology, Chinese Academy of Sciences ; Autonomous Project of the Institute of Hydrobiology, Chinese Academy of Sciences ; Autonomous Project of the Institute of Hydrobiology, Chinese Academy of Sciences ; Autonomous Project of the Institute of Hydrobiology, Chinese Academy of Sciences ; Autonomous Project of the Institute of Hydrobiology, Chinese Academy of Sciences ; Strategic Priority Research Program of the Chinese Academy of Sciences ; Strategic Priority Research Program of the Chinese Academy of Sciences ; Strategic Priority Research Program of the Chinese Academy of Sciences ; Strategic Priority Research Program of the Chinese Academy of Sciences ; Strategic Priority Research Program of the Chinese Academy of Sciences ; Strategic Priority Research Program of the Chinese Academy of Sciences ; Strategic Priority Research Program of the Chinese Academy of Sciences ; Strategic Priority Research Program of the Chinese Academy of Sciences ; Autonomous Project of the State Key Laboratory of Freshwater Ecology and Biotechnology ; Autonomous Project of the State Key Laboratory of Freshwater Ecology and Biotechnology ; Autonomous Project of the State Key Laboratory of Freshwater Ecology and Biotechnology ; Autonomous Project of the State Key Laboratory of Freshwater Ecology and Biotechnology ; Autonomous Project of the State Key Laboratory of Freshwater Ecology and Biotechnology ; Autonomous Project of the State Key Laboratory of Freshwater Ecology and Biotechnology ; Autonomous Project of the State Key Laboratory of Freshwater Ecology and Biotechnology ; Autonomous Project of the State Key Laboratory of Freshwater Ecology and Biotechnology ; Autonomous Project of the Institute of Hydrobiology, Chinese Academy of Sciences ; Autonomous Project of the Institute of Hydrobiology, Chinese Academy of Sciences ; Autonomous Project of the Institute of Hydrobiology, Chinese Academy of Sciences ; Autonomous Project of the Institute of Hydrobiology, Chinese Academy of Sciences ; Autonomous Project of the Institute of Hydrobiology, Chinese Academy of Sciences ; Autonomous Project of the Institute of Hydrobiology, Chinese Academy of Sciences ; Autonomous Project of the Institute of Hydrobiology, Chinese Academy of Sciences ; Autonomous Project of the Institute of Hydrobiology, Chinese Academy of Sciences ; Strategic Priority Research Program of the Chinese Academy of Sciences ; Strategic Priority Research Program of the Chinese Academy of Sciences ; Strategic Priority Research Program of the Chinese Academy of Sciences ; Strategic Priority Research Program of the Chinese Academy of Sciences ; Strategic Priority Research Program of the Chinese Academy of Sciences ; Strategic Priority Research Program of the Chinese Academy of Sciences ; Strategic Priority Research Program of the Chinese Academy of Sciences ; Strategic Priority Research Program of the Chinese Academy of Sciences ; Autonomous Project of the State Key Laboratory of Freshwater Ecology and Biotechnology ; Autonomous Project of the State Key Laboratory of Freshwater Ecology and Biotechnology ; Autonomous Project of the State Key Laboratory of Freshwater Ecology and Biotechnology ; Autonomous Project of the State Key Laboratory of Freshwater Ecology and Biotechnology ; Autonomous Project of the State Key Laboratory of Freshwater Ecology and Biotechnology ; Autonomous Project of the State Key Laboratory of Freshwater Ecology and Biotechnology ; Autonomous Project of the State Key Laboratory of Freshwater Ecology and Biotechnology ; Autonomous Project of the State Key Laboratory of Freshwater Ecology and Biotechnology ; Autonomous Project of the Institute of Hydrobiology, Chinese Academy of Sciences ; Autonomous Project of the Institute of Hydrobiology, Chinese Academy of Sciences ; Autonomous Project of the Institute of Hydrobiology, Chinese Academy of Sciences ; Autonomous Project of the Institute of Hydrobiology, Chinese Academy of Sciences ; Autonomous Project of the Institute of Hydrobiology, Chinese Academy of Sciences ; Autonomous Project of the Institute of Hydrobiology, Chinese Academy of Sciences ; Autonomous Project of the Institute of Hydrobiology, Chinese Academy of Sciences ; Autonomous Project of the Institute of Hydrobiology, Chinese Academy of Sciences ; Strategic Priority Research Program of the Chinese Academy of Sciences ; Strategic Priority Research Program of the Chinese Academy of Sciences ; Strategic Priority Research Program of the Chinese Academy of Sciences ; Strategic Priority Research Program of the Chinese Academy of Sciences ; Strategic Priority Research Program of the Chinese Academy of Sciences ; Strategic Priority Research Program of the Chinese Academy of Sciences ; Strategic Priority Research Program of the Chinese Academy of Sciences ; Strategic Priority Research Program of the Chinese Academy of Sciences ; Autonomous Project of the State Key Laboratory of Freshwater Ecology and Biotechnology ; Autonomous Project of the State Key Laboratory of Freshwater Ecology and Biotechnology ; Autonomous Project of the State Key Laboratory of Freshwater Ecology and Biotechnology ; Autonomous Project of the State Key Laboratory of Freshwater Ecology and Biotechnology ; Autonomous Project of the State Key Laboratory of Freshwater Ecology and Biotechnology ; Autonomous Project of the State Key Laboratory of Freshwater Ecology and Biotechnology ; Autonomous Project of the State Key Laboratory of Freshwater Ecology and Biotechnology ; Autonomous Project of the State Key Laboratory of Freshwater Ecology and Biotechnology ; Autonomous Project of the Institute of Hydrobiology, Chinese Academy of Sciences ; Autonomous Project of the Institute of Hydrobiology, Chinese Academy of Sciences ; Autonomous Project of the Institute of Hydrobiology, Chinese Academy of Sciences ; Autonomous Project of the Institute of Hydrobiology, Chinese Academy of Sciences ; Autonomous Project of the Institute of Hydrobiology, Chinese Academy of Sciences ; Autonomous Project of the Institute of Hydrobiology, Chinese Academy of Sciences ; Autonomous Project of the Institute of Hydrobiology, Chinese Academy of Sciences ; Autonomous Project of the Institute of Hydrobiology, Chinese Academy of Sciences ; Strategic Priority Research Program of the Chinese Academy of Sciences ; Strategic Priority Research Program of the Chinese Academy of Sciences ; Strategic Priority Research Program of the Chinese Academy of Sciences ; Strategic Priority Research Program of the Chinese Academy of Sciences ; Strategic Priority Research Program of the Chinese Academy of Sciences ; Strategic Priority Research Program of the Chinese Academy of Sciences ; Strategic Priority Research Program of the Chinese Academy of Sciences ; Strategic Priority Research Program of the Chinese Academy of Sciences ; Autonomous Project of the State Key Laboratory of Freshwater Ecology and Biotechnology ; Autonomous Project of the State Key Laboratory of Freshwater Ecology and Biotechnology ; Autonomous Project of the State Key Laboratory of Freshwater Ecology and Biotechnology ; Autonomous Project of the State Key Laboratory of Freshwater Ecology and Biotechnology ; Autonomous Project of the State Key Laboratory of Freshwater Ecology and Biotechnology ; Autonomous Project of the State Key Laboratory of Freshwater Ecology and Biotechnology ; Autonomous Project of the State Key Laboratory of Freshwater Ecology and Biotechnology ; Autonomous Project of the State Key Laboratory of Freshwater Ecology and Biotechnology ; Autonomous Project of the Institute of Hydrobiology, Chinese Academy of Sciences ; Autonomous Project of the Institute of Hydrobiology, Chinese Academy of Sciences ; Autonomous Project of the Institute of Hydrobiology, Chinese Academy of Sciences ; Autonomous Project of the Institute of Hydrobiology, Chinese Academy of Sciences ; Autonomous Project of the Institute of Hydrobiology, Chinese Academy of Sciences ; Autonomous Project of the Institute of Hydrobiology, Chinese Academy of Sciences ; Autonomous Project of the Institute of Hydrobiology, Chinese Academy of Sciences ; Autonomous Project of the Institute of Hydrobiology, Chinese Academy of Sciences ; Strategic Priority Research Program of the Chinese Academy of Sciences ; Strategic Priority Research Program of the Chinese Academy of Sciences ; Strategic Priority Research Program of the Chinese Academy of Sciences ; Strategic Priority Research Program of the Chinese Academy of Sciences ; Strategic Priority Research Program of the Chinese Academy of Sciences ; Strategic Priority Research Program of the Chinese Academy of Sciences ; Strategic Priority Research Program of the Chinese Academy of Sciences ; Strategic Priority Research Program of the Chinese Academy of Sciences ; Autonomous Project of the State Key Laboratory of Freshwater Ecology and Biotechnology ; Autonomous Project of the State Key Laboratory of Freshwater Ecology and Biotechnology ; Autonomous Project of the State Key Laboratory of Freshwater Ecology and Biotechnology ; Autonomous Project of the State Key Laboratory of Freshwater Ecology and Biotechnology ; Autonomous Project of the State Key Laboratory of Freshwater Ecology and Biotechnology ; Autonomous Project of the State Key Laboratory of Freshwater Ecology and Biotechnology ; Autonomous Project of the State Key Laboratory of Freshwater Ecology and Biotechnology ; Autonomous Project of the State Key Laboratory of Freshwater Ecology and Biotechnology ; Autonomous Project of the Institute of Hydrobiology, Chinese Academy of Sciences ; Autonomous Project of the Institute of Hydrobiology, Chinese Academy of Sciences ; Autonomous Project of the Institute of Hydrobiology, Chinese Academy of Sciences ; Autonomous Project of the Institute of Hydrobiology, Chinese Academy of Sciences ; Autonomous Project of the Institute of Hydrobiology, Chinese Academy of Sciences ; Autonomous Project of the Institute of Hydrobiology, Chinese Academy of Sciences ; Autonomous Project of the Institute of Hydrobiology, Chinese Academy of Sciences ; Autonomous Project of the Institute of Hydrobiology, Chinese Academy of Sciences ; Strategic Priority Research Program of the Chinese Academy of Sciences ; Strategic Priority Research Program of the Chinese Academy of Sciences ; Strategic Priority Research Program of the Chinese Academy of Sciences ; Strategic Priority Research Program of the Chinese Academy of Sciences ; Strategic Priority Research Program of the Chinese Academy of Sciences ; Strategic Priority Research Program of the Chinese Academy of Sciences ; Strategic Priority Research Program of the Chinese Academy of Sciences ; Strategic Priority Research Program of the Chinese Academy of Sciences ; Autonomous Project of the State Key Laboratory of Freshwater Ecology and Biotechnology ; Autonomous Project of the State Key Laboratory of Freshwater Ecology and Biotechnology ; Autonomous Project of the State Key Laboratory of Freshwater Ecology and Biotechnology ; Autonomous Project of the State Key Laboratory of Freshwater Ecology and Biotechnology ; Autonomous Project of the State Key Laboratory of Freshwater Ecology and Biotechnology ; Autonomous Project of the State Key Laboratory of Freshwater Ecology and Biotechnology ; Autonomous Project of the State Key Laboratory of Freshwater Ecology and Biotechnology ; Autonomous Project of the State Key Laboratory of Freshwater Ecology and Biotechnology ; Autonomous Project of the Institute of Hydrobiology, Chinese Academy of Sciences ; Autonomous Project of the Institute of Hydrobiology, Chinese Academy of Sciences ; Autonomous Project of the Institute of Hydrobiology, Chinese Academy of Sciences ; Autonomous Project of the Institute of Hydrobiology, Chinese Academy of Sciences ; Autonomous Project of the Institute of Hydrobiology, Chinese Academy of Sciences ; Autonomous Project of the Institute of Hydrobiology, Chinese Academy of Sciences ; Autonomous Project of the Institute of Hydrobiology, Chinese Academy of Sciences ; Autonomous Project of the Institute of Hydrobiology, Chinese Academy of Sciences
Indexed BySCI
Language英语
Funding ProjectStrategic Priority Research Program of the Chinese Academy of Sciences[XDA08030201] ; Autonomous Project of the State Key Laboratory of Freshwater Ecology and Biotechnology[2016FBZ01] ; Autonomous Project of the Institute of Hydrobiology, Chinese Academy of Sciences[Y25A171]
WOS Research AreaGenetics & Heredity
WOS SubjectGenetics & Heredity
WOS IDWOS:000401126600015
WOS KeywordGONADAL SEX-DIFFERENTIATION ; ANTI-MULLERIAN HORMONE ; FORKHEAD TRANSCRIPTION FACTORS ; SEXUALLY DIMORPHIC EXPRESSION ; AROMATASE GENE-TRANSCRIPTION ; POLYPLOID GIBEL CARP ; DM-DOMAIN GENE ; MOLECULAR-CLONING ; DANIO-RERIO ; GERM-CELLS
PublisherGENETICS SOCIETY AMERICA
Funding OrganizationStrategic Priority Research Program of the Chinese Academy of Sciences ; Strategic Priority Research Program of the Chinese Academy of Sciences ; Strategic Priority Research Program of the Chinese Academy of Sciences ; Strategic Priority Research Program of the Chinese Academy of Sciences ; Strategic Priority Research Program of the Chinese Academy of Sciences ; Strategic Priority Research Program of the Chinese Academy of Sciences ; Strategic Priority Research Program of the Chinese Academy of Sciences ; Strategic Priority Research Program of the Chinese Academy of Sciences ; Autonomous Project of the State Key Laboratory of Freshwater Ecology and Biotechnology ; Autonomous Project of the State Key Laboratory of Freshwater Ecology and Biotechnology ; Autonomous Project of the State Key Laboratory of Freshwater Ecology and Biotechnology ; Autonomous Project of the State Key Laboratory of Freshwater Ecology and Biotechnology ; Autonomous Project of the State Key Laboratory of Freshwater Ecology and Biotechnology ; Autonomous Project of the State Key Laboratory of Freshwater Ecology and Biotechnology ; Autonomous Project of the State Key Laboratory of Freshwater Ecology and Biotechnology ; Autonomous Project of the State Key Laboratory of Freshwater Ecology and Biotechnology ; Autonomous Project of the Institute of Hydrobiology, Chinese Academy of Sciences ; Autonomous Project of the Institute of Hydrobiology, Chinese Academy of Sciences ; Autonomous Project of the Institute of Hydrobiology, Chinese Academy of Sciences ; Autonomous Project of the Institute of Hydrobiology, Chinese Academy of Sciences ; Autonomous Project of the Institute of Hydrobiology, Chinese Academy of Sciences ; Autonomous Project of the Institute of Hydrobiology, Chinese Academy of Sciences ; Autonomous Project of the Institute of Hydrobiology, Chinese Academy of Sciences ; Autonomous Project of the Institute of Hydrobiology, Chinese Academy of Sciences ; Strategic Priority Research Program of the Chinese Academy of Sciences ; Strategic Priority Research Program of the Chinese Academy of Sciences ; Strategic Priority Research Program of the Chinese Academy of Sciences ; Strategic Priority Research Program of the Chinese Academy of Sciences ; Strategic Priority Research Program of the Chinese Academy of Sciences ; Strategic Priority Research Program of the Chinese Academy of Sciences ; Strategic Priority Research Program of the Chinese Academy of Sciences ; Strategic Priority Research Program of the Chinese Academy of Sciences ; Autonomous Project of the State Key Laboratory of Freshwater Ecology and Biotechnology ; Autonomous Project of the State Key Laboratory of Freshwater Ecology and Biotechnology ; Autonomous Project of the State Key Laboratory of Freshwater Ecology and Biotechnology ; Autonomous Project of the State Key Laboratory of Freshwater Ecology and Biotechnology ; Autonomous Project of the State Key Laboratory of Freshwater Ecology and Biotechnology ; Autonomous Project of the State Key Laboratory of Freshwater Ecology and Biotechnology ; Autonomous Project of the State Key Laboratory of Freshwater Ecology and Biotechnology ; Autonomous Project of the State Key Laboratory of Freshwater Ecology and Biotechnology ; Autonomous Project of the Institute of Hydrobiology, Chinese Academy of Sciences ; Autonomous Project of the Institute of Hydrobiology, Chinese Academy of Sciences ; Autonomous Project of the Institute of Hydrobiology, Chinese Academy of Sciences ; Autonomous Project of the Institute of Hydrobiology, Chinese Academy of Sciences ; Autonomous Project of the Institute of Hydrobiology, Chinese Academy of Sciences ; Autonomous Project of the Institute of Hydrobiology, Chinese Academy of Sciences ; Autonomous Project of the Institute of Hydrobiology, Chinese Academy of Sciences ; Autonomous Project of the Institute of Hydrobiology, Chinese Academy of Sciences ; Strategic Priority Research Program of the Chinese Academy of Sciences ; Strategic Priority Research Program of the Chinese Academy of Sciences ; Strategic Priority Research Program of the Chinese Academy of Sciences ; Strategic Priority Research Program of the Chinese Academy of Sciences ; Strategic Priority Research Program of the Chinese Academy of Sciences ; Strategic Priority Research Program of the Chinese Academy of Sciences ; Strategic Priority Research Program of the Chinese Academy of Sciences ; Strategic Priority Research Program of the Chinese Academy of Sciences ; Autonomous Project of the State Key Laboratory of Freshwater Ecology and Biotechnology ; Autonomous Project of the State Key Laboratory of Freshwater Ecology and Biotechnology ; Autonomous Project of the State Key Laboratory of Freshwater Ecology and Biotechnology ; Autonomous Project of the State Key Laboratory of Freshwater Ecology and Biotechnology ; Autonomous Project of the State Key Laboratory of Freshwater Ecology and Biotechnology ; Autonomous Project of the State Key Laboratory of Freshwater Ecology and Biotechnology ; Autonomous Project of the State Key Laboratory of Freshwater Ecology and Biotechnology ; Autonomous Project of the State Key Laboratory of Freshwater Ecology and Biotechnology ; Autonomous Project of the Institute of Hydrobiology, Chinese Academy of Sciences ; Autonomous Project of the Institute of Hydrobiology, Chinese Academy of Sciences ; Autonomous Project of the Institute of Hydrobiology, Chinese Academy of Sciences ; Autonomous Project of the Institute of Hydrobiology, Chinese Academy of Sciences ; Autonomous Project of the Institute of Hydrobiology, Chinese Academy of Sciences ; Autonomous Project of the Institute of Hydrobiology, Chinese Academy of Sciences ; Autonomous Project of the Institute of Hydrobiology, Chinese Academy of Sciences ; Autonomous Project of the Institute of Hydrobiology, Chinese Academy of Sciences ; Strategic Priority Research Program of the Chinese Academy of Sciences ; Strategic Priority Research Program of the Chinese Academy of Sciences ; Strategic Priority Research Program of the Chinese Academy of Sciences ; Strategic Priority Research Program of the Chinese Academy of Sciences ; Strategic Priority Research Program of the Chinese Academy of Sciences ; Strategic Priority Research Program of the Chinese Academy of Sciences ; Strategic Priority Research Program of the Chinese Academy of Sciences ; Strategic Priority Research Program of the Chinese Academy of Sciences ; Autonomous Project of the State Key Laboratory of Freshwater Ecology and Biotechnology ; Autonomous Project of the State Key Laboratory of Freshwater Ecology and Biotechnology ; Autonomous Project of the State Key Laboratory of Freshwater Ecology and Biotechnology ; Autonomous Project of the State Key Laboratory of Freshwater Ecology and Biotechnology ; Autonomous Project of the State Key Laboratory of Freshwater Ecology and Biotechnology ; Autonomous Project of the State Key Laboratory of Freshwater Ecology and Biotechnology ; Autonomous Project of the State Key Laboratory of Freshwater Ecology and Biotechnology ; Autonomous Project of the State Key Laboratory of Freshwater Ecology and Biotechnology ; Autonomous Project of the Institute of Hydrobiology, Chinese Academy of Sciences ; Autonomous Project of the Institute of Hydrobiology, Chinese Academy of Sciences ; Autonomous Project of the Institute of Hydrobiology, Chinese Academy of Sciences ; Autonomous Project of the Institute of Hydrobiology, Chinese Academy of Sciences ; Autonomous Project of the Institute of Hydrobiology, Chinese Academy of Sciences ; Autonomous Project of the Institute of Hydrobiology, Chinese Academy of Sciences ; Autonomous Project of the Institute of Hydrobiology, Chinese Academy of Sciences ; Autonomous Project of the Institute of Hydrobiology, Chinese Academy of Sciences ; Strategic Priority Research Program of the Chinese Academy of Sciences ; Strategic Priority Research Program of the Chinese Academy of Sciences ; Strategic Priority Research Program of the Chinese Academy of Sciences ; Strategic Priority Research Program of the Chinese Academy of Sciences ; Strategic Priority Research Program of the Chinese Academy of Sciences ; Strategic Priority Research Program of the Chinese Academy of Sciences ; Strategic Priority Research Program of the Chinese Academy of Sciences ; Strategic Priority Research Program of the Chinese Academy of Sciences ; Autonomous Project of the State Key Laboratory of Freshwater Ecology and Biotechnology ; Autonomous Project of the State Key Laboratory of Freshwater Ecology and Biotechnology ; Autonomous Project of the State Key Laboratory of Freshwater Ecology and Biotechnology ; Autonomous Project of the State Key Laboratory of Freshwater Ecology and Biotechnology ; Autonomous Project of the State Key Laboratory of Freshwater Ecology and Biotechnology ; Autonomous Project of the State Key Laboratory of Freshwater Ecology and Biotechnology ; Autonomous Project of the State Key Laboratory of Freshwater Ecology and Biotechnology ; Autonomous Project of the State Key Laboratory of Freshwater Ecology and Biotechnology ; Autonomous Project of the Institute of Hydrobiology, Chinese Academy of Sciences ; Autonomous Project of the Institute of Hydrobiology, Chinese Academy of Sciences ; Autonomous Project of the Institute of Hydrobiology, Chinese Academy of Sciences ; Autonomous Project of the Institute of Hydrobiology, Chinese Academy of Sciences ; Autonomous Project of the Institute of Hydrobiology, Chinese Academy of Sciences ; Autonomous Project of the Institute of Hydrobiology, Chinese Academy of Sciences ; Autonomous Project of the Institute of Hydrobiology, Chinese Academy of Sciences ; Autonomous Project of the Institute of Hydrobiology, Chinese Academy of Sciences ; Strategic Priority Research Program of the Chinese Academy of Sciences ; Strategic Priority Research Program of the Chinese Academy of Sciences ; Strategic Priority Research Program of the Chinese Academy of Sciences ; Strategic Priority Research Program of the Chinese Academy of Sciences ; Strategic Priority Research Program of the Chinese Academy of Sciences ; Strategic Priority Research Program of the Chinese Academy of Sciences ; Strategic Priority Research Program of the Chinese Academy of Sciences ; Strategic Priority Research Program of the Chinese Academy of Sciences ; Autonomous Project of the State Key Laboratory of Freshwater Ecology and Biotechnology ; Autonomous Project of the State Key Laboratory of Freshwater Ecology and Biotechnology ; Autonomous Project of the State Key Laboratory of Freshwater Ecology and Biotechnology ; Autonomous Project of the State Key Laboratory of Freshwater Ecology and Biotechnology ; Autonomous Project of the State Key Laboratory of Freshwater Ecology and Biotechnology ; Autonomous Project of the State Key Laboratory of Freshwater Ecology and Biotechnology ; Autonomous Project of the State Key Laboratory of Freshwater Ecology and Biotechnology ; Autonomous Project of the State Key Laboratory of Freshwater Ecology and Biotechnology ; Autonomous Project of the Institute of Hydrobiology, Chinese Academy of Sciences ; Autonomous Project of the Institute of Hydrobiology, Chinese Academy of Sciences ; Autonomous Project of the Institute of Hydrobiology, Chinese Academy of Sciences ; Autonomous Project of the Institute of Hydrobiology, Chinese Academy of Sciences ; Autonomous Project of the Institute of Hydrobiology, Chinese Academy of Sciences ; Autonomous Project of the Institute of Hydrobiology, Chinese Academy of Sciences ; Autonomous Project of the Institute of Hydrobiology, Chinese Academy of Sciences ; Autonomous Project of the Institute of Hydrobiology, Chinese Academy of Sciences ; Strategic Priority Research Program of the Chinese Academy of Sciences ; Strategic Priority Research Program of the Chinese Academy of Sciences ; Strategic Priority Research Program of the Chinese Academy of Sciences ; Strategic Priority Research Program of the Chinese Academy of Sciences ; Strategic Priority Research Program of the Chinese Academy of Sciences ; Strategic Priority Research Program of the Chinese Academy of Sciences ; Strategic Priority Research Program of the Chinese Academy of Sciences ; Strategic Priority Research Program of the Chinese Academy of Sciences ; Autonomous Project of the State Key Laboratory of Freshwater Ecology and Biotechnology ; Autonomous Project of the State Key Laboratory of Freshwater Ecology and Biotechnology ; Autonomous Project of the State Key Laboratory of Freshwater Ecology and Biotechnology ; Autonomous Project of the State Key Laboratory of Freshwater Ecology and Biotechnology ; Autonomous Project of the State Key Laboratory of Freshwater Ecology and Biotechnology ; Autonomous Project of the State Key Laboratory of Freshwater Ecology and Biotechnology ; Autonomous Project of the State Key Laboratory of Freshwater Ecology and Biotechnology ; Autonomous Project of the State Key Laboratory of Freshwater Ecology and Biotechnology ; Autonomous Project of the Institute of Hydrobiology, Chinese Academy of Sciences ; Autonomous Project of the Institute of Hydrobiology, Chinese Academy of Sciences ; Autonomous Project of the Institute of Hydrobiology, Chinese Academy of Sciences ; Autonomous Project of the Institute of Hydrobiology, Chinese Academy of Sciences ; Autonomous Project of the Institute of Hydrobiology, Chinese Academy of Sciences ; Autonomous Project of the Institute of Hydrobiology, Chinese Academy of Sciences ; Autonomous Project of the Institute of Hydrobiology, Chinese Academy of Sciences ; Autonomous Project of the Institute of Hydrobiology, Chinese Academy of Sciences ; Strategic Priority Research Program of the Chinese Academy of Sciences ; Strategic Priority Research Program of the Chinese Academy of Sciences ; Strategic Priority Research Program of the Chinese Academy of Sciences ; Strategic Priority Research Program of the Chinese Academy of Sciences ; Strategic Priority Research Program of the Chinese Academy of Sciences ; Strategic Priority Research Program of the Chinese Academy of Sciences ; Strategic Priority Research Program of the Chinese Academy of Sciences ; Strategic Priority Research Program of the Chinese Academy of Sciences ; Autonomous Project of the State Key Laboratory of Freshwater Ecology and Biotechnology ; Autonomous Project of the State Key Laboratory of Freshwater Ecology and Biotechnology ; Autonomous Project of the State Key Laboratory of Freshwater Ecology and Biotechnology ; Autonomous Project of the State Key Laboratory of Freshwater Ecology and Biotechnology ; Autonomous Project of the State Key Laboratory of Freshwater Ecology and Biotechnology ; Autonomous Project of the State Key Laboratory of Freshwater Ecology and Biotechnology ; Autonomous Project of the State Key Laboratory of Freshwater Ecology and Biotechnology ; Autonomous Project of the State Key Laboratory of Freshwater Ecology and Biotechnology ; Autonomous Project of the Institute of Hydrobiology, Chinese Academy of Sciences ; Autonomous Project of the Institute of Hydrobiology, Chinese Academy of Sciences ; Autonomous Project of the Institute of Hydrobiology, Chinese Academy of Sciences ; Autonomous Project of the Institute of Hydrobiology, Chinese Academy of Sciences ; Autonomous Project of the Institute of Hydrobiology, Chinese Academy of Sciences ; Autonomous Project of the Institute of Hydrobiology, Chinese Academy of Sciences ; Autonomous Project of the Institute of Hydrobiology, Chinese Academy of Sciences ; Autonomous Project of the Institute of Hydrobiology, Chinese Academy of Sciences
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Cited Times:29[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.ihb.ac.cn/handle/342005/32541
Collection鱼类生物学及渔业生物技术研究中心_期刊论文
Corresponding AuthorZhou, Li; Gui, Jian-Fang
Affiliation1.Chinese Acad Sci, Inst Hydrobiol, State Key Lab Freshwater Ecol & Biotechnol, Wuhan 430072, Peoples R China
2.Chinese Acad Sci, Grad Univ, Wuhan 430072, Peoples R China
Recommended Citation
GB/T 7714
Yang, Yan-Jing,Wang, Yang,Li, Zhi,et al. Sequential, Divergent, and Cooperative Requirements of Foxl2a and Foxl2b in Ovary Development and Maintenance of Zebrafish[J]. GENETICS,2017,205(4):1551-1572.
APA Yang, Yan-Jing,Wang, Yang,Li, Zhi,Zhou, Li,&Gui, Jian-Fang.(2017).Sequential, Divergent, and Cooperative Requirements of Foxl2a and Foxl2b in Ovary Development and Maintenance of Zebrafish.GENETICS,205(4),1551-1572.
MLA Yang, Yan-Jing,et al."Sequential, Divergent, and Cooperative Requirements of Foxl2a and Foxl2b in Ovary Development and Maintenance of Zebrafish".GENETICS 205.4(2017):1551-1572.
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