Developmental neurotoxicity of reserpine exposure in zebrafish larvae (Danio rerio) | |
Wang, Shao1,2; Duan, Ming3; Guan, Kaiyu1,2; Zhou, Xianyong1,2; Zheng, Miaomiao1,2; Shi, Xulai4; Ye, Minjie1,2; Guan, Wanchun2,5; Kuver, Aarti2; Huang, Manli6,7; Liu, Yunbing8; Dai, Kezhi1,2; Li, Xi1,2 | |
2019-09-01 | |
Source Publication | COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY
![]() |
ISSN | 1532-0456 |
Volume | 223Issue:1Pages:115-123 |
Abstract | Reserpine is widely used for treatment of hypertension and schizophrenia. As a specific inhibitor of monoamine transporters, reserpine is known to deplete monoamine neurotransmitters and cause decreased movement symptoms. However, how zebrafish larvae respond to reserpine treatment is not well studied. Here we show that swimming distance and average velocity are significantly reduced after reserpine exposure under various stimulatory conditions. Using liquid chromatograph mass spectrometer analysis, decreased levels of monoamines (e.g. dopamine, noradrenaline, and serotonin) were detected in reserpine-treated larvae. Moreover, reserpine treatment significantly reduced the number of dopaminergic neurons, which was identified with th (Tyrosine Hydroxylase) in situ hybridization in the preoptic area. Interestingly, dopaminergic neuron development-associated genes, such as otpa, otpb, wnt1, wnt3, wnt5 and manf; were downregulated in reserpine treated larvae. Our data indicates that 2 mg/L reserpine exposure induces dopaminergic neuron damage in the brain, demonstrating a chemical induced depression-like model in zebrafish larvae for future drug development. |
Keyword | Reserpine Dopaminergic system Zebrafish larvae |
DOI | 10.1016/j.cbpc.2019.05.008 |
Funding Organization | National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; Science and Technology Department of Zhejiang Province ; Science and Technology Department of Zhejiang Province ; Science and Technology Department of Zhejiang Province ; Science and Technology Department of Zhejiang Province ; Science and Technology Department of Zhejiang Province ; Science and Technology Department of Zhejiang Province ; Science and Technology Department of Zhejiang Province ; Science and Technology Department of Zhejiang Province ; Student Science and Technology Innovation Activity Plan of Zhejiang Province ; Student Science and Technology Innovation Activity Plan of Zhejiang Province ; Student Science and Technology Innovation Activity Plan of Zhejiang Province ; Student Science and Technology Innovation Activity Plan of Zhejiang Province ; Student Science and Technology Innovation Activity Plan of Zhejiang Province ; Student Science and Technology Innovation Activity Plan of Zhejiang Province ; Student Science and Technology Innovation Activity Plan of Zhejiang Province ; Student Science and Technology Innovation Activity Plan of Zhejiang Province ; Wenzhou Municipal Science and Technology Bureau Program ; Wenzhou Municipal Science and Technology Bureau Program ; Wenzhou Municipal Science and Technology Bureau Program ; Wenzhou Municipal Science and Technology Bureau Program ; Wenzhou Municipal Science and Technology Bureau Program ; Wenzhou Municipal Science and Technology Bureau Program ; Wenzhou Municipal Science and Technology Bureau Program ; Wenzhou Municipal Science and Technology Bureau Program ; Wenzhou Medical and Health Research Project ; Wenzhou Medical and Health Research Project ; Wenzhou Medical and Health Research Project ; Wenzhou Medical and Health Research Project ; Wenzhou Medical and Health Research Project ; Wenzhou Medical and Health Research Project ; Wenzhou Medical and Health Research Project ; Wenzhou Medical and Health Research Project ; Key Research Project of Zhejiang Province ; Key Research Project of Zhejiang Province ; Key Research Project of Zhejiang Province ; Key Research Project of Zhejiang Province ; Key Research Project of Zhejiang Province ; Key Research Project of Zhejiang Province ; Key Research Project of Zhejiang Province ; Key Research Project of Zhejiang Province ; Zhejiang Province Science & Technology (Laboratory Animal) Project ; Zhejiang Province Science & Technology (Laboratory Animal) Project ; Zhejiang Province Science & Technology (Laboratory Animal) Project ; Zhejiang Province Science & Technology (Laboratory Animal) Project ; Zhejiang Province Science & Technology (Laboratory Animal) Project ; Zhejiang Province Science & Technology (Laboratory Animal) Project ; Zhejiang Province Science & Technology (Laboratory Animal) Project ; Zhejiang Province Science & Technology (Laboratory Animal) Project ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; Science and Technology Department of Zhejiang Province ; Science and Technology Department of Zhejiang Province ; Science and Technology Department of Zhejiang Province ; Science and Technology Department of Zhejiang Province ; Science and Technology Department of Zhejiang Province ; Science and Technology Department of Zhejiang Province ; Science and Technology Department of Zhejiang Province ; Science and Technology Department of Zhejiang Province ; Student Science and Technology Innovation Activity Plan of Zhejiang Province ; Student Science and Technology Innovation Activity Plan of Zhejiang Province ; Student Science and Technology Innovation Activity Plan of Zhejiang Province ; Student Science and Technology Innovation Activity Plan of Zhejiang Province ; Student Science and Technology Innovation Activity Plan of Zhejiang Province ; Student Science and Technology Innovation Activity Plan of Zhejiang Province ; Student Science and Technology Innovation Activity Plan of Zhejiang Province ; Student Science and Technology Innovation Activity Plan of Zhejiang Province ; Wenzhou Municipal Science and Technology Bureau Program ; Wenzhou Municipal Science and Technology Bureau Program ; Wenzhou Municipal Science and Technology Bureau Program ; Wenzhou Municipal Science and Technology Bureau Program ; Wenzhou Municipal Science and Technology Bureau Program ; Wenzhou Municipal Science and Technology Bureau Program ; Wenzhou Municipal Science and Technology Bureau Program ; Wenzhou Municipal Science and Technology Bureau Program ; Wenzhou Medical and Health Research Project ; Wenzhou Medical and Health Research Project ; Wenzhou Medical and Health Research Project ; Wenzhou Medical and Health Research Project ; Wenzhou Medical and Health Research Project ; Wenzhou Medical and Health Research Project ; Wenzhou Medical and Health Research Project ; Wenzhou Medical and Health Research Project ; Key Research Project of Zhejiang Province ; Key Research Project of Zhejiang Province ; Key Research Project of Zhejiang Province ; Key Research Project of Zhejiang Province ; Key Research Project of Zhejiang Province ; Key Research Project of Zhejiang Province ; Key Research Project of Zhejiang Province ; Key Research Project of Zhejiang Province ; Zhejiang Province Science & Technology (Laboratory Animal) Project ; Zhejiang Province Science & Technology (Laboratory Animal) Project ; Zhejiang Province Science & Technology (Laboratory Animal) Project ; Zhejiang Province Science & Technology (Laboratory Animal) Project ; Zhejiang Province Science & Technology (Laboratory Animal) Project ; Zhejiang Province Science & Technology (Laboratory Animal) Project ; Zhejiang Province Science & Technology (Laboratory Animal) Project ; Zhejiang Province Science & Technology (Laboratory Animal) Project ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; Science and Technology Department of Zhejiang Province ; Science and Technology Department of Zhejiang Province ; Science and Technology Department of Zhejiang Province ; Science and Technology Department of Zhejiang Province ; Science and Technology Department of Zhejiang Province ; Science and Technology Department of Zhejiang Province ; Science and Technology Department of Zhejiang Province ; Science and Technology Department of Zhejiang Province ; Student Science and Technology Innovation Activity Plan of Zhejiang Province ; Student Science and Technology Innovation Activity Plan of Zhejiang Province ; Student Science and Technology Innovation Activity Plan of Zhejiang Province ; Student Science and Technology Innovation Activity Plan of Zhejiang Province ; Student Science and Technology Innovation Activity Plan of Zhejiang Province ; Student Science and Technology Innovation Activity Plan of Zhejiang Province ; Student Science and Technology Innovation Activity Plan of Zhejiang Province ; Student Science and Technology Innovation Activity Plan of Zhejiang Province ; Wenzhou Municipal Science and Technology Bureau Program ; Wenzhou Municipal Science and Technology Bureau Program ; Wenzhou Municipal Science and Technology Bureau Program ; Wenzhou Municipal Science and Technology Bureau Program ; Wenzhou Municipal Science and Technology Bureau Program ; Wenzhou Municipal Science and Technology Bureau Program ; Wenzhou Municipal Science and Technology Bureau Program ; Wenzhou Municipal Science and Technology Bureau Program ; Wenzhou Medical and Health Research Project ; Wenzhou Medical and Health Research Project ; Wenzhou Medical and Health Research Project ; Wenzhou Medical and Health Research Project ; Wenzhou Medical and Health Research Project ; Wenzhou Medical and Health Research Project ; Wenzhou Medical and Health Research Project ; Wenzhou Medical and Health Research Project ; Key Research Project of Zhejiang Province ; Key Research Project of Zhejiang Province ; Key Research Project of Zhejiang Province ; Key Research Project of Zhejiang Province ; Key Research Project of Zhejiang Province ; Key Research Project of Zhejiang Province ; Key Research Project of Zhejiang Province ; Key Research Project of Zhejiang Province ; Zhejiang Province Science & Technology (Laboratory Animal) Project ; Zhejiang Province Science & Technology (Laboratory Animal) Project ; Zhejiang Province Science & Technology (Laboratory Animal) Project ; Zhejiang Province Science & Technology (Laboratory Animal) Project ; Zhejiang Province Science & Technology (Laboratory Animal) Project ; Zhejiang Province Science & Technology (Laboratory Animal) Project ; Zhejiang Province Science & Technology (Laboratory Animal) Project ; Zhejiang Province Science & Technology (Laboratory Animal) Project ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; Science and Technology Department of Zhejiang Province ; Science and Technology Department of Zhejiang Province ; Science and Technology Department of Zhejiang Province ; Science and Technology Department of Zhejiang Province ; Science and Technology Department of Zhejiang Province ; Science and Technology Department of Zhejiang Province ; Science and Technology Department of Zhejiang Province ; Science and Technology Department of Zhejiang Province ; Student Science and Technology Innovation Activity Plan of Zhejiang Province ; Student Science and Technology Innovation Activity Plan of Zhejiang Province ; Student Science and Technology Innovation Activity Plan of Zhejiang Province ; Student Science and Technology Innovation Activity Plan of Zhejiang Province ; Student Science and Technology Innovation Activity Plan of Zhejiang Province ; Student Science and Technology Innovation Activity Plan of Zhejiang Province ; Student Science and Technology Innovation Activity Plan of Zhejiang Province ; Student Science and Technology Innovation Activity Plan of Zhejiang Province ; Wenzhou Municipal Science and Technology Bureau Program ; Wenzhou Municipal Science and Technology Bureau Program ; Wenzhou Municipal Science and Technology Bureau Program ; Wenzhou Municipal Science and Technology Bureau Program ; Wenzhou Municipal Science and Technology Bureau Program ; Wenzhou Municipal Science and Technology Bureau Program ; Wenzhou Municipal Science and Technology Bureau Program ; Wenzhou Municipal Science and Technology Bureau Program ; Wenzhou Medical and Health Research Project ; Wenzhou Medical and Health Research Project ; Wenzhou Medical and Health Research Project ; Wenzhou Medical and Health Research Project ; Wenzhou Medical and Health Research Project ; Wenzhou Medical and Health Research Project ; Wenzhou Medical and Health Research Project ; Wenzhou Medical and Health Research Project ; Key Research Project of Zhejiang Province ; Key Research Project of Zhejiang Province ; Key Research Project of Zhejiang Province ; Key Research Project of Zhejiang Province ; Key Research Project of Zhejiang Province ; Key Research Project of Zhejiang Province ; Key Research Project of Zhejiang Province ; Key Research Project of Zhejiang Province ; Zhejiang Province Science & Technology (Laboratory Animal) Project ; Zhejiang Province Science & Technology (Laboratory Animal) Project ; Zhejiang Province Science & Technology (Laboratory Animal) Project ; Zhejiang Province Science & Technology (Laboratory Animal) Project ; Zhejiang Province Science & Technology (Laboratory Animal) Project ; Zhejiang Province Science & Technology (Laboratory Animal) Project ; Zhejiang Province Science & Technology (Laboratory Animal) Project ; Zhejiang Province Science & Technology (Laboratory Animal) Project ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; Science and Technology Department of Zhejiang Province ; Science and Technology Department of Zhejiang Province ; Science and Technology Department of Zhejiang Province ; Science and Technology Department of Zhejiang Province ; Science and Technology Department of Zhejiang Province ; Science and Technology Department of Zhejiang Province ; Science and Technology Department of Zhejiang Province ; Science and Technology Department of Zhejiang Province ; Student Science and Technology Innovation Activity Plan of Zhejiang Province ; Student Science and Technology Innovation Activity Plan of Zhejiang Province ; Student Science and Technology Innovation Activity Plan of Zhejiang Province ; Student Science and Technology Innovation Activity Plan of Zhejiang Province ; Student Science and Technology Innovation Activity Plan of Zhejiang Province ; Student Science and Technology Innovation Activity Plan of Zhejiang Province ; Student Science and Technology Innovation Activity Plan of Zhejiang Province ; Student Science and Technology Innovation Activity Plan of Zhejiang Province ; Wenzhou Municipal Science and Technology Bureau Program ; Wenzhou Municipal Science and Technology Bureau Program ; Wenzhou Municipal Science and Technology Bureau Program ; Wenzhou Municipal Science and Technology Bureau Program ; Wenzhou Municipal Science and Technology Bureau Program ; Wenzhou Municipal Science and Technology Bureau Program ; Wenzhou Municipal Science and Technology Bureau Program ; Wenzhou Municipal Science and Technology Bureau Program ; Wenzhou Medical and Health Research Project ; Wenzhou Medical and Health Research Project ; Wenzhou Medical and Health Research Project ; Wenzhou Medical and Health Research Project ; Wenzhou Medical and Health Research Project ; Wenzhou Medical and Health Research Project ; Wenzhou Medical and Health Research Project ; Wenzhou Medical and Health Research Project ; Key Research Project of Zhejiang Province ; Key Research Project of Zhejiang Province ; Key Research Project of Zhejiang Province ; Key Research Project of Zhejiang Province ; Key Research Project of Zhejiang Province ; Key Research Project of Zhejiang Province ; Key Research Project of Zhejiang Province ; Key Research Project of Zhejiang Province ; Zhejiang Province Science & Technology (Laboratory Animal) Project ; Zhejiang Province Science & Technology (Laboratory Animal) Project ; Zhejiang Province Science & Technology (Laboratory Animal) Project ; Zhejiang Province Science & Technology (Laboratory Animal) Project ; Zhejiang Province Science & Technology (Laboratory Animal) Project ; Zhejiang Province Science & Technology (Laboratory Animal) Project ; Zhejiang Province Science & Technology (Laboratory Animal) Project ; Zhejiang Province Science & Technology (Laboratory Animal) Project ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; Science and Technology Department of Zhejiang Province ; Science and Technology Department of Zhejiang Province ; Science and Technology Department of Zhejiang Province ; Science and Technology Department of Zhejiang Province ; Science and Technology Department of Zhejiang Province ; Science and Technology Department of Zhejiang Province ; Science and Technology Department of Zhejiang Province ; Science and Technology Department of Zhejiang Province ; Student Science and Technology Innovation Activity Plan of Zhejiang Province ; Student Science and Technology Innovation Activity Plan of Zhejiang Province ; Student Science and Technology Innovation Activity Plan of Zhejiang Province ; Student Science and Technology Innovation Activity Plan of Zhejiang Province ; Student Science and Technology Innovation Activity Plan of Zhejiang Province ; Student Science and Technology Innovation Activity Plan of Zhejiang Province ; Student Science and Technology Innovation Activity Plan of Zhejiang Province ; Student Science and Technology Innovation Activity Plan of Zhejiang Province ; Wenzhou Municipal Science and Technology Bureau Program ; Wenzhou Municipal Science and Technology Bureau Program ; Wenzhou Municipal Science and Technology Bureau Program ; Wenzhou Municipal Science and Technology Bureau Program ; Wenzhou Municipal Science and Technology Bureau Program ; Wenzhou Municipal Science and Technology Bureau Program ; Wenzhou Municipal Science and Technology Bureau Program ; Wenzhou Municipal Science and Technology Bureau Program ; Wenzhou Medical and Health Research Project ; Wenzhou Medical and Health Research Project ; Wenzhou Medical and Health Research Project ; Wenzhou Medical and Health Research Project ; Wenzhou Medical and Health Research Project ; Wenzhou Medical and Health Research Project ; Wenzhou Medical and Health Research Project ; Wenzhou Medical and Health Research Project ; Key Research Project of Zhejiang Province ; Key Research Project of Zhejiang Province ; Key Research Project of Zhejiang Province ; Key Research Project of Zhejiang Province ; Key Research Project of Zhejiang Province ; Key Research Project of Zhejiang Province ; Key Research Project of Zhejiang Province ; Key Research Project of Zhejiang Province ; Zhejiang Province Science & Technology (Laboratory Animal) Project ; Zhejiang Province Science & Technology (Laboratory Animal) Project ; Zhejiang Province Science & Technology (Laboratory Animal) Project ; Zhejiang Province Science & Technology (Laboratory Animal) Project ; Zhejiang Province Science & Technology (Laboratory Animal) Project ; Zhejiang Province Science & Technology (Laboratory Animal) Project ; Zhejiang Province Science & Technology (Laboratory Animal) Project ; Zhejiang Province Science & Technology (Laboratory Animal) Project ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; Science and Technology Department of Zhejiang Province ; Science and Technology Department of Zhejiang Province ; Science and Technology Department of Zhejiang Province ; Science and Technology Department of Zhejiang Province ; Science and Technology Department of Zhejiang Province ; Science and Technology Department of Zhejiang Province ; Science and Technology Department of Zhejiang Province ; Science and Technology Department of Zhejiang Province ; Student Science and Technology Innovation Activity Plan of Zhejiang Province ; Student Science and Technology Innovation Activity Plan of Zhejiang Province ; Student Science and Technology Innovation Activity Plan of Zhejiang Province ; Student Science and Technology Innovation Activity Plan of Zhejiang Province ; Student Science and Technology Innovation Activity Plan of Zhejiang Province ; Student Science and Technology Innovation Activity Plan of Zhejiang Province ; Student Science and Technology Innovation Activity Plan of Zhejiang Province ; Student Science and Technology Innovation Activity Plan of Zhejiang Province ; Wenzhou Municipal Science and Technology Bureau Program ; Wenzhou Municipal Science and Technology Bureau Program ; Wenzhou Municipal Science and Technology Bureau Program ; Wenzhou Municipal Science and Technology Bureau Program ; Wenzhou Municipal Science and Technology Bureau Program ; Wenzhou Municipal Science and Technology Bureau Program ; Wenzhou Municipal Science and Technology Bureau Program ; Wenzhou Municipal Science and Technology Bureau Program ; Wenzhou Medical and Health Research Project ; Wenzhou Medical and Health Research Project ; Wenzhou Medical and Health Research Project ; Wenzhou Medical and Health Research Project ; Wenzhou Medical and Health Research Project ; Wenzhou Medical and Health Research Project ; Wenzhou Medical and Health Research Project ; Wenzhou Medical and Health Research Project ; Key Research Project of Zhejiang Province ; Key Research Project of Zhejiang Province ; Key Research Project of Zhejiang Province ; Key Research Project of Zhejiang Province ; Key Research Project of Zhejiang Province ; Key Research Project of Zhejiang Province ; Key Research Project of Zhejiang Province ; Key Research Project of Zhejiang Province ; Zhejiang Province Science & Technology (Laboratory Animal) Project ; Zhejiang Province Science & Technology (Laboratory Animal) Project ; Zhejiang Province Science & Technology (Laboratory Animal) Project ; Zhejiang Province Science & Technology (Laboratory Animal) Project ; Zhejiang Province Science & Technology (Laboratory Animal) Project ; Zhejiang Province Science & Technology (Laboratory Animal) Project ; Zhejiang Province Science & Technology (Laboratory Animal) Project ; Zhejiang Province Science & Technology (Laboratory Animal) Project ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; Science and Technology Department of Zhejiang Province ; Science and Technology Department of Zhejiang Province ; Science and Technology Department of Zhejiang Province ; Science and Technology Department of Zhejiang Province ; Science and Technology Department of Zhejiang Province ; Science and Technology Department of Zhejiang Province ; Science and Technology Department of Zhejiang Province ; Science and Technology Department of Zhejiang Province ; Student Science and Technology Innovation Activity Plan of Zhejiang Province ; Student Science and Technology Innovation Activity Plan of Zhejiang Province ; Student Science and Technology Innovation Activity Plan of Zhejiang Province ; Student Science and Technology Innovation Activity Plan of Zhejiang Province ; Student Science and Technology Innovation Activity Plan of Zhejiang Province ; Student Science and Technology Innovation Activity Plan of Zhejiang Province ; Student Science and Technology Innovation Activity Plan of Zhejiang Province ; Student Science and Technology Innovation Activity Plan of Zhejiang Province ; Wenzhou Municipal Science and Technology Bureau Program ; Wenzhou Municipal Science and Technology Bureau Program ; Wenzhou Municipal Science and Technology Bureau Program ; Wenzhou Municipal Science and Technology Bureau Program ; Wenzhou Municipal Science and Technology Bureau Program ; Wenzhou Municipal Science and Technology Bureau Program ; Wenzhou Municipal Science and Technology Bureau Program ; Wenzhou Municipal Science and Technology Bureau Program ; Wenzhou Medical and Health Research Project ; Wenzhou Medical and Health Research Project ; Wenzhou Medical and Health Research Project ; Wenzhou Medical and Health Research Project ; Wenzhou Medical and Health Research Project ; Wenzhou Medical and Health Research Project ; Wenzhou Medical and Health Research Project ; Wenzhou Medical and Health Research Project ; Key Research Project of Zhejiang Province ; Key Research Project of Zhejiang Province ; Key Research Project of Zhejiang Province ; Key Research Project of Zhejiang Province ; Key Research Project of Zhejiang Province ; Key Research Project of Zhejiang Province ; Key Research Project of Zhejiang Province ; Key Research Project of Zhejiang Province ; Zhejiang Province Science & Technology (Laboratory Animal) Project ; Zhejiang Province Science & Technology (Laboratory Animal) Project ; Zhejiang Province Science & Technology (Laboratory Animal) Project ; Zhejiang Province Science & Technology (Laboratory Animal) Project ; Zhejiang Province Science & Technology (Laboratory Animal) Project ; Zhejiang Province Science & Technology (Laboratory Animal) Project ; Zhejiang Province Science & Technology (Laboratory Animal) Project ; Zhejiang Province Science & Technology (Laboratory Animal) Project |
Indexed By | SCI |
Language | 英语 |
Funding Project | National Natural Science Foundation of China[81673643] ; National Natural Science Foundation of China[31501146] ; National Natural Science Foundation of China[31471269] ; Science and Technology Department of Zhejiang Province[2012C23066] ; Science and Technology Department of Zhejiang Province[LQ15C120001] ; Student Science and Technology Innovation Activity Plan of Zhejiang Province[2018R413030] ; Student Science and Technology Innovation Activity Plan of Zhejiang Province[2018R413185] ; Wenzhou Municipal Science and Technology Bureau Program[Y20170017] ; Wenzhou Municipal Science and Technology Bureau Program[Y20160195] ; Wenzhou Medical and Health Research Project[2018A09] ; Wenzhou Medical and Health Research Project[2018A10] ; Key Research Project of Zhejiang Province[2015C03040] ; Zhejiang Province Science & Technology (Laboratory Animal) Project[2017C37127] |
WOS Research Area | Biochemistry & Molecular Biology ; Endocrinology & Metabolism ; Toxicology ; Zoology |
WOS Subject | Biochemistry & Molecular Biology ; Endocrinology & Metabolism ; Toxicology ; Zoology |
WOS ID | WOS:000477686100014 |
WOS Keyword | DOPAMINERGIC NEURON DEVELOPMENT ; PARKINSONS-DISEASE ; DEPRESSION ; MODEL ; MOTOR ; EXPRESSION ; MONOAMINES ; AGONIST ; RATS |
Publisher | ELSEVIER SCIENCE INC |
Funding Organization | National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; Science and Technology Department of Zhejiang Province ; Science and Technology Department of Zhejiang Province ; Science and Technology Department of Zhejiang Province ; Science and Technology Department of Zhejiang Province ; Science and Technology Department of Zhejiang Province ; Science and Technology Department of Zhejiang Province ; Science and Technology Department of Zhejiang Province ; Science and Technology Department of Zhejiang Province ; Student Science and Technology Innovation Activity Plan of Zhejiang Province ; Student Science and Technology Innovation Activity Plan of Zhejiang Province ; Student Science and Technology Innovation Activity Plan of Zhejiang Province ; Student Science and Technology Innovation Activity Plan of Zhejiang Province ; Student Science and Technology Innovation Activity Plan of Zhejiang Province ; Student Science and Technology Innovation Activity Plan of Zhejiang Province ; Student Science and Technology Innovation Activity Plan of Zhejiang Province ; Student Science and Technology Innovation Activity Plan of Zhejiang Province ; Wenzhou Municipal Science and Technology Bureau Program ; Wenzhou Municipal Science and Technology Bureau Program ; Wenzhou Municipal Science and Technology Bureau Program ; Wenzhou Municipal Science and Technology Bureau Program ; Wenzhou Municipal Science and Technology Bureau Program ; Wenzhou Municipal Science and Technology Bureau Program ; Wenzhou Municipal Science and Technology Bureau Program ; Wenzhou Municipal Science and Technology Bureau Program ; Wenzhou Medical and Health Research Project ; Wenzhou Medical and Health Research Project ; Wenzhou Medical and Health Research Project ; Wenzhou Medical and Health Research Project ; Wenzhou Medical and Health Research Project ; Wenzhou Medical and Health Research Project ; Wenzhou Medical and Health Research Project ; Wenzhou Medical and Health Research Project ; Key Research Project of Zhejiang Province ; Key Research Project of Zhejiang Province ; Key Research Project of Zhejiang Province ; Key Research Project of Zhejiang Province ; Key Research Project of Zhejiang Province ; Key Research Project of Zhejiang Province ; Key Research Project of Zhejiang Province ; Key Research Project of Zhejiang Province ; Zhejiang Province Science & Technology (Laboratory Animal) Project ; Zhejiang Province Science & Technology (Laboratory Animal) Project ; Zhejiang Province Science & Technology (Laboratory Animal) Project ; Zhejiang Province Science & Technology (Laboratory Animal) Project ; Zhejiang Province Science & Technology (Laboratory Animal) Project ; Zhejiang Province Science & Technology (Laboratory Animal) Project ; Zhejiang Province Science & Technology (Laboratory Animal) Project ; Zhejiang Province Science & Technology (Laboratory Animal) Project ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; Science and Technology Department of Zhejiang Province ; Science and Technology Department of Zhejiang Province ; Science and Technology Department of Zhejiang Province ; Science and Technology Department of Zhejiang Province ; Science and Technology Department of Zhejiang Province ; Science and Technology Department of Zhejiang Province ; Science and Technology Department of Zhejiang Province ; Science and Technology Department of Zhejiang Province ; Student Science and Technology Innovation Activity Plan of Zhejiang Province ; Student Science and Technology Innovation Activity Plan of Zhejiang Province ; Student Science and Technology Innovation Activity Plan of Zhejiang Province ; Student Science and Technology Innovation Activity Plan of Zhejiang Province ; Student Science and Technology Innovation Activity Plan of Zhejiang Province ; Student Science and Technology Innovation Activity Plan of Zhejiang Province ; Student Science and Technology Innovation Activity Plan of Zhejiang Province ; Student Science and Technology Innovation Activity Plan of Zhejiang Province ; Wenzhou Municipal Science and Technology Bureau Program ; Wenzhou Municipal Science and Technology Bureau Program ; Wenzhou Municipal Science and Technology Bureau Program ; Wenzhou Municipal Science and Technology Bureau Program ; Wenzhou Municipal Science and Technology Bureau Program ; Wenzhou Municipal Science and Technology Bureau Program ; Wenzhou Municipal Science and Technology Bureau Program ; Wenzhou Municipal Science and Technology Bureau Program ; Wenzhou Medical and Health Research Project ; Wenzhou Medical and Health Research Project ; Wenzhou Medical and Health Research Project ; Wenzhou Medical and Health Research Project ; Wenzhou Medical and Health Research Project ; Wenzhou Medical and Health Research Project ; Wenzhou Medical and Health Research Project ; Wenzhou Medical and Health Research Project ; Key Research Project of Zhejiang Province ; Key Research Project of Zhejiang Province ; Key Research Project of Zhejiang Province ; Key Research Project of Zhejiang Province ; Key Research Project of Zhejiang Province ; Key Research Project of Zhejiang Province ; Key Research Project of Zhejiang Province ; Key Research Project of Zhejiang Province ; Zhejiang Province Science & Technology (Laboratory Animal) Project ; Zhejiang Province Science & Technology (Laboratory Animal) Project ; Zhejiang Province Science & Technology (Laboratory Animal) Project ; Zhejiang Province Science & Technology (Laboratory Animal) Project ; Zhejiang Province Science & Technology (Laboratory Animal) Project ; Zhejiang Province Science & Technology (Laboratory Animal) Project ; Zhejiang Province Science & Technology (Laboratory Animal) Project ; Zhejiang Province Science & Technology (Laboratory Animal) Project ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; Science and Technology Department of Zhejiang Province ; Science and Technology Department of Zhejiang Province ; Science and Technology Department of Zhejiang Province ; Science and Technology Department of Zhejiang Province ; Science and Technology Department of Zhejiang Province ; Science and Technology Department of Zhejiang Province ; Science and Technology Department of Zhejiang Province ; Science and Technology Department of Zhejiang Province ; Student Science and Technology Innovation Activity Plan of Zhejiang Province ; Student Science and Technology Innovation Activity Plan of Zhejiang Province ; Student Science and Technology Innovation Activity Plan of Zhejiang Province ; Student Science and Technology Innovation Activity Plan of Zhejiang Province ; Student Science and Technology Innovation Activity Plan of Zhejiang Province ; Student Science and Technology Innovation Activity Plan of Zhejiang Province ; Student Science and Technology Innovation Activity Plan of Zhejiang Province ; Student Science and Technology Innovation Activity Plan of Zhejiang Province ; Wenzhou Municipal Science and Technology Bureau Program ; Wenzhou Municipal Science and Technology Bureau Program ; Wenzhou Municipal Science and Technology Bureau Program ; Wenzhou Municipal Science and Technology Bureau Program ; Wenzhou Municipal Science and Technology Bureau Program ; Wenzhou Municipal Science and Technology Bureau Program ; Wenzhou Municipal Science and Technology Bureau Program ; Wenzhou Municipal Science and Technology Bureau Program ; Wenzhou Medical and Health Research Project ; Wenzhou Medical and Health Research Project ; Wenzhou Medical and Health Research Project ; Wenzhou Medical and Health Research Project ; Wenzhou Medical and Health Research Project ; Wenzhou Medical and Health Research Project ; Wenzhou Medical and Health Research Project ; Wenzhou Medical and Health Research Project ; Key Research Project of Zhejiang Province ; Key Research Project of Zhejiang Province ; Key Research Project of Zhejiang Province ; Key Research Project of Zhejiang Province ; Key Research Project of Zhejiang Province ; Key Research Project of Zhejiang Province ; Key Research Project of Zhejiang Province ; Key Research Project of Zhejiang Province ; Zhejiang Province Science & Technology (Laboratory Animal) Project ; Zhejiang Province Science & Technology (Laboratory Animal) Project ; Zhejiang Province Science & Technology (Laboratory Animal) Project ; Zhejiang Province Science & Technology (Laboratory Animal) Project ; Zhejiang Province Science & Technology (Laboratory Animal) Project ; Zhejiang Province Science & Technology (Laboratory Animal) Project ; Zhejiang Province Science & Technology (Laboratory Animal) Project ; Zhejiang Province Science & Technology (Laboratory Animal) Project ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; Science and Technology Department of Zhejiang Province ; Science and Technology Department of Zhejiang Province ; Science and Technology Department of Zhejiang Province ; Science and Technology Department of Zhejiang Province ; Science and Technology Department of Zhejiang Province ; Science and Technology Department of Zhejiang Province ; Science and Technology Department of Zhejiang Province ; Science and Technology Department of Zhejiang Province ; Student Science and Technology Innovation Activity Plan of Zhejiang Province ; Student Science and Technology Innovation Activity Plan of Zhejiang Province ; Student Science and Technology Innovation Activity Plan of Zhejiang Province ; Student Science and Technology Innovation Activity Plan of Zhejiang Province ; Student Science and Technology Innovation Activity Plan of Zhejiang Province ; Student Science and Technology Innovation Activity Plan of Zhejiang Province ; Student Science and Technology Innovation Activity Plan of Zhejiang Province ; Student Science and Technology Innovation Activity Plan of Zhejiang Province ; Wenzhou Municipal Science and Technology Bureau Program ; Wenzhou Municipal Science and Technology Bureau Program ; Wenzhou Municipal Science and Technology Bureau Program ; Wenzhou Municipal Science and Technology Bureau Program ; Wenzhou Municipal Science and Technology Bureau Program ; Wenzhou Municipal Science and Technology Bureau Program ; Wenzhou Municipal Science and Technology Bureau Program ; Wenzhou Municipal Science and Technology Bureau Program ; Wenzhou Medical and Health Research Project ; Wenzhou Medical and Health Research Project ; Wenzhou Medical and Health Research Project ; Wenzhou Medical and Health Research Project ; Wenzhou Medical and Health Research Project ; Wenzhou Medical and Health Research Project ; Wenzhou Medical and Health Research Project ; Wenzhou Medical and Health Research Project ; Key Research Project of Zhejiang Province ; Key Research Project of Zhejiang Province ; Key Research Project of Zhejiang Province ; Key Research Project of Zhejiang Province ; Key Research Project of Zhejiang Province ; Key Research Project of Zhejiang Province ; Key Research Project of Zhejiang Province ; Key Research Project of Zhejiang Province ; Zhejiang Province Science & Technology (Laboratory Animal) Project ; Zhejiang Province Science & Technology (Laboratory Animal) Project ; Zhejiang Province Science & Technology (Laboratory Animal) Project ; Zhejiang Province Science & Technology (Laboratory Animal) Project ; Zhejiang Province Science & Technology (Laboratory Animal) Project ; Zhejiang Province Science & Technology (Laboratory Animal) Project ; Zhejiang Province Science & Technology (Laboratory Animal) Project ; Zhejiang Province Science & Technology (Laboratory Animal) Project ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; Science and Technology Department of Zhejiang Province ; Science and Technology Department of Zhejiang Province ; Science and Technology Department of Zhejiang Province ; Science and Technology Department of Zhejiang Province ; Science and Technology Department of Zhejiang Province ; Science and Technology Department of Zhejiang Province ; Science and Technology Department of Zhejiang Province ; Science and Technology Department of Zhejiang Province ; Student Science and Technology Innovation Activity Plan of Zhejiang Province ; Student Science and Technology Innovation Activity Plan of Zhejiang Province ; Student Science and Technology Innovation Activity Plan of Zhejiang Province ; Student Science and Technology Innovation Activity Plan of Zhejiang Province ; Student Science and Technology Innovation Activity Plan of Zhejiang Province ; Student Science and Technology Innovation Activity Plan of Zhejiang Province ; Student Science and Technology Innovation Activity Plan of Zhejiang Province ; Student Science and Technology Innovation Activity Plan of Zhejiang Province ; Wenzhou Municipal Science and Technology Bureau Program ; Wenzhou Municipal Science and Technology Bureau Program ; Wenzhou Municipal Science and Technology Bureau Program ; Wenzhou Municipal Science and Technology Bureau Program ; Wenzhou Municipal Science and Technology Bureau Program ; Wenzhou Municipal Science and Technology Bureau Program ; Wenzhou Municipal Science and Technology Bureau Program ; Wenzhou Municipal Science and Technology Bureau Program ; Wenzhou Medical and Health Research Project ; Wenzhou Medical and Health Research Project ; Wenzhou Medical and Health Research Project ; Wenzhou Medical and Health Research Project ; Wenzhou Medical and Health Research Project ; Wenzhou Medical and Health Research Project ; Wenzhou Medical and Health Research Project ; Wenzhou Medical and Health Research Project ; Key Research Project of Zhejiang Province ; Key Research Project of Zhejiang Province ; Key Research Project of Zhejiang Province ; Key Research Project of Zhejiang Province ; Key Research Project of Zhejiang Province ; Key Research Project of Zhejiang Province ; Key Research Project of Zhejiang Province ; Key Research Project of Zhejiang Province ; Zhejiang Province Science & Technology (Laboratory Animal) Project ; Zhejiang Province Science & Technology (Laboratory Animal) Project ; Zhejiang Province Science & Technology (Laboratory Animal) Project ; Zhejiang Province Science & Technology (Laboratory Animal) Project ; Zhejiang Province Science & Technology (Laboratory Animal) Project ; Zhejiang Province Science & Technology (Laboratory Animal) Project ; Zhejiang Province Science & Technology (Laboratory Animal) Project ; Zhejiang Province Science & Technology (Laboratory Animal) Project ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; Science and Technology Department of Zhejiang Province ; Science and Technology Department of Zhejiang Province ; Science and Technology Department of Zhejiang Province ; Science and Technology Department of Zhejiang Province ; Science and Technology Department of Zhejiang Province ; Science and Technology Department of Zhejiang Province ; Science and Technology Department of Zhejiang Province ; Science and Technology Department of Zhejiang Province ; Student Science and Technology Innovation Activity Plan of Zhejiang Province ; Student Science and Technology Innovation Activity Plan of Zhejiang Province ; Student Science and Technology Innovation Activity Plan of Zhejiang Province ; Student Science and Technology Innovation Activity Plan of Zhejiang Province ; Student Science and Technology Innovation Activity Plan of Zhejiang Province ; Student Science and Technology Innovation Activity Plan of Zhejiang Province ; Student Science and Technology Innovation Activity Plan of Zhejiang Province ; Student Science and Technology Innovation Activity Plan of Zhejiang Province ; Wenzhou Municipal Science and Technology Bureau Program ; Wenzhou Municipal Science and Technology Bureau Program ; Wenzhou Municipal Science and Technology Bureau Program ; Wenzhou Municipal Science and Technology Bureau Program ; Wenzhou Municipal Science and Technology Bureau Program ; Wenzhou Municipal Science and Technology Bureau Program ; Wenzhou Municipal Science and Technology Bureau Program ; Wenzhou Municipal Science and Technology Bureau Program ; Wenzhou Medical and Health Research Project ; Wenzhou Medical and Health Research Project ; Wenzhou Medical and Health Research Project ; Wenzhou Medical and Health Research Project ; Wenzhou Medical and Health Research Project ; Wenzhou Medical and Health Research Project ; Wenzhou Medical and Health Research Project ; Wenzhou Medical and Health Research Project ; Key Research Project of Zhejiang Province ; Key Research Project of Zhejiang Province ; Key Research Project of Zhejiang Province ; Key Research Project of Zhejiang Province ; Key Research Project of Zhejiang Province ; Key Research Project of Zhejiang Province ; Key Research Project of Zhejiang Province ; Key Research Project of Zhejiang Province ; Zhejiang Province Science & Technology (Laboratory Animal) Project ; Zhejiang Province Science & Technology (Laboratory Animal) Project ; Zhejiang Province Science & Technology (Laboratory Animal) Project ; Zhejiang Province Science & Technology (Laboratory Animal) Project ; Zhejiang Province Science & Technology (Laboratory Animal) Project ; Zhejiang Province Science & Technology (Laboratory Animal) Project ; Zhejiang Province Science & Technology (Laboratory Animal) Project ; Zhejiang Province Science & Technology (Laboratory Animal) Project ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; Science and Technology Department of Zhejiang Province ; Science and Technology Department of Zhejiang Province ; Science and Technology Department of Zhejiang Province ; Science and Technology Department of Zhejiang Province ; Science and Technology Department of Zhejiang Province ; Science and Technology Department of Zhejiang Province ; Science and Technology Department of Zhejiang Province ; Science and Technology Department of Zhejiang Province ; Student Science and Technology Innovation Activity Plan of Zhejiang Province ; Student Science and Technology Innovation Activity Plan of Zhejiang Province ; Student Science and Technology Innovation Activity Plan of Zhejiang Province ; Student Science and Technology Innovation Activity Plan of Zhejiang Province ; Student Science and Technology Innovation Activity Plan of Zhejiang Province ; Student Science and Technology Innovation Activity Plan of Zhejiang Province ; Student Science and Technology Innovation Activity Plan of Zhejiang Province ; Student Science and Technology Innovation Activity Plan of Zhejiang Province ; Wenzhou Municipal Science and Technology Bureau Program ; Wenzhou Municipal Science and Technology Bureau Program ; Wenzhou Municipal Science and Technology Bureau Program ; Wenzhou Municipal Science and Technology Bureau Program ; Wenzhou Municipal Science and Technology Bureau Program ; Wenzhou Municipal Science and Technology Bureau Program ; Wenzhou Municipal Science and Technology Bureau Program ; Wenzhou Municipal Science and Technology Bureau Program ; Wenzhou Medical and Health Research Project ; Wenzhou Medical and Health Research Project ; Wenzhou Medical and Health Research Project ; Wenzhou Medical and Health Research Project ; Wenzhou Medical and Health Research Project ; Wenzhou Medical and Health Research Project ; Wenzhou Medical and Health Research Project ; Wenzhou Medical and Health Research Project ; Key Research Project of Zhejiang Province ; Key Research Project of Zhejiang Province ; Key Research Project of Zhejiang Province ; Key Research Project of Zhejiang Province ; Key Research Project of Zhejiang Province ; Key Research Project of Zhejiang Province ; Key Research Project of Zhejiang Province ; Key Research Project of Zhejiang Province ; Zhejiang Province Science & Technology (Laboratory Animal) Project ; Zhejiang Province Science & Technology (Laboratory Animal) Project ; Zhejiang Province Science & Technology (Laboratory Animal) Project ; Zhejiang Province Science & Technology (Laboratory Animal) Project ; Zhejiang Province Science & Technology (Laboratory Animal) Project ; Zhejiang Province Science & Technology (Laboratory Animal) Project ; Zhejiang Province Science & Technology (Laboratory Animal) Project ; Zhejiang Province Science & Technology (Laboratory Animal) Project ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; Science and Technology Department of Zhejiang Province ; Science and Technology Department of Zhejiang Province ; Science and Technology Department of Zhejiang Province ; Science and Technology Department of Zhejiang Province ; Science and Technology Department of Zhejiang Province ; Science and Technology Department of Zhejiang Province ; Science and Technology Department of Zhejiang Province ; Science and Technology Department of Zhejiang Province ; Student Science and Technology Innovation Activity Plan of Zhejiang Province ; Student Science and Technology Innovation Activity Plan of Zhejiang Province ; Student Science and Technology Innovation Activity Plan of Zhejiang Province ; Student Science and Technology Innovation Activity Plan of Zhejiang Province ; Student Science and Technology Innovation Activity Plan of Zhejiang Province ; Student Science and Technology Innovation Activity Plan of Zhejiang Province ; Student Science and Technology Innovation Activity Plan of Zhejiang Province ; Student Science and Technology Innovation Activity Plan of Zhejiang Province ; Wenzhou Municipal Science and Technology Bureau Program ; Wenzhou Municipal Science and Technology Bureau Program ; Wenzhou Municipal Science and Technology Bureau Program ; Wenzhou Municipal Science and Technology Bureau Program ; Wenzhou Municipal Science and Technology Bureau Program ; Wenzhou Municipal Science and Technology Bureau Program ; Wenzhou Municipal Science and Technology Bureau Program ; Wenzhou Municipal Science and Technology Bureau Program ; Wenzhou Medical and Health Research Project ; Wenzhou Medical and Health Research Project ; Wenzhou Medical and Health Research Project ; Wenzhou Medical and Health Research Project ; Wenzhou Medical and Health Research Project ; Wenzhou Medical and Health Research Project ; Wenzhou Medical and Health Research Project ; Wenzhou Medical and Health Research Project ; Key Research Project of Zhejiang Province ; Key Research Project of Zhejiang Province ; Key Research Project of Zhejiang Province ; Key Research Project of Zhejiang Province ; Key Research Project of Zhejiang Province ; Key Research Project of Zhejiang Province ; Key Research Project of Zhejiang Province ; Key Research Project of Zhejiang Province ; Zhejiang Province Science & Technology (Laboratory Animal) Project ; Zhejiang Province Science & Technology (Laboratory Animal) Project ; Zhejiang Province Science & Technology (Laboratory Animal) Project ; Zhejiang Province Science & Technology (Laboratory Animal) Project ; Zhejiang Province Science & Technology (Laboratory Animal) Project ; Zhejiang Province Science & Technology (Laboratory Animal) Project ; Zhejiang Province Science & Technology (Laboratory Animal) Project ; Zhejiang Province Science & Technology (Laboratory Animal) Project |
Citation statistics | |
Document Type | 期刊论文 |
Identifier | http://ir.ihb.ac.cn/handle/342005/32171 |
Collection | 中科院水生所知识产出(2009年前) |
Corresponding Author | Dai, Kezhi; Li, Xi |
Affiliation | 1.Wenzhou Med Univ, Affiliated Kangning Hosp, 1 Shengjin Rd, Wenzhou 325000, Zhejiang, Peoples R China 2.Wenzhou Med Univ, Sch Mental Hlth, Wenzhou 32500, Zhejiang, Peoples R China 3.Chinese Acad Sci, Inst Hydrobiol, State Key Lab Freshwater Ecol & Biotechnol, Wuhan 430072, Hubei, Peoples R China 4.Wenzhou Med Univ, Affiliated Hosp 2, Wenzhou 325000, Zhejiang, Peoples R China 5.Wenzhou Med Univ, Sch Lab Med & Life Sci, Wenzhou 325000, Zhejiang, Peoples R China 6.Zhejiang Univ, Affiliated Hosp 1, Sch Med, Dept Psychiat, Hangzhou 310003, Zhejiang, Peoples R China 7.Key Lab Mental Disorder Management Zhejiang Prov, Hangzhou 310003, Zhejiang, Peoples R China 8.Yangtze Valley Water Environm Monitoring Ctr, 13 Yongqing Branch Rd, Wuhan 430010, Hubei, Peoples R China |
Recommended Citation GB/T 7714 | Wang, Shao,Duan, Ming,Guan, Kaiyu,et al. Developmental neurotoxicity of reserpine exposure in zebrafish larvae (Danio rerio)[J]. COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY,2019,223(1):115-123. |
APA | Wang, Shao.,Duan, Ming.,Guan, Kaiyu.,Zhou, Xianyong.,Zheng, Miaomiao.,...&Li, Xi.(2019).Developmental neurotoxicity of reserpine exposure in zebrafish larvae (Danio rerio).COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY,223(1),115-123. |
MLA | Wang, Shao,et al."Developmental neurotoxicity of reserpine exposure in zebrafish larvae (Danio rerio)".COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY 223.1(2019):115-123. |
Files in This Item: | ||||||
File Name/Size | DocType | Version | Access | License | ||
1-s2.0-S153204561930(1823KB) | 期刊论文 | 作者接受稿 | 开放获取 | CC BY-NC-SA | View Application Full Text |
Items in the repository are protected by copyright, with all rights reserved, unless otherwise indicated.
Edit Comment