| Evidence of high-altitude adaptation in the glyptosternoid fish, Creteuchiloglanis macropterus from the Nujiang River obtained through transcriptome analysis | |
| Kang, Jingliang1,2; Ma, Xiuhui3; He, Shunping1 | |
| Corresponding Author | He, Shunping(clad@ihb.ac.cn) |
| 2017-11-23 | |
| Source Publication | BMC EVOLUTIONARY BIOLOGY
 |
| ISSN | 1471-2148 |
| Volume | 17Pages:12 |
| Abstract | Background: Organisms living at high altitudes face low oxygen and temperature conditions; thus, the genetic mechanisms underlying the adaptations in these organisms merit investigation. The glyptosternoid fish, Creteuchiloglanis macropterus mainly inhabits regions with gradual increases in altitudes along the Nujiang River and might serve as an appropriate evolutionary model for detecting adaptation processes in environments with altitude changes. Results: We constructed eleven RNA-sequencing (RNA-seq) libraries of C. macropterus collected from five locations at different altitudes to identify the genetic signatures of high-altitude adaptation. The comparative genomic analysis indicated that C. macropterus has an accelerated evolutionary rate compared with that of fishes in the lowland, and fishes at higher altitudes might evolve faster. Functional enrichment analysis of the fast-evolving and positively selected genes, differentially expressed genes and highly expressed genes, showed that these genes were involved in many functions related to energy metabolism and hypoxia. Conclusions: Our study provides evidence of high-altitude adaptation in C. macropterus, and the detected adaptive genes might be a resource for future investigations of adaptations to high-altitude environments in other fishes. |
| Keyword | Creteuchiloglanis macropterus The Nujiang River Transcriptome High-altitude adaptation Gene expression |
| DOI | 10.1186/s12862-017-1074-0 |
| Funding Organization | Pilot projects ; Pilot projects ; Pilot projects ; Pilot projects ; Pilot projects ; Pilot projects ; Pilot projects ; Pilot projects ; Pilot projects ; Pilot projects ; Pilot projects ; Pilot projects ; Pilot projects ; Pilot projects ; Pilot projects ; Pilot projects |
| Indexed By | SCI ; SCI |
| Language | 英语 |
| Funding Project | Pilot projects[XDB13020100] |
| WOS Research Area | Evolutionary Biology ; Genetics & Heredity |
| WOS Subject | Evolutionary Biology ; Genetics & Heredity |
| WOS ID | WOS:000416062200002 |
| WOS Keyword | GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE EXPRESSION ; OXIDATIVE DNA-DAMAGE ; NUCLEOTIDE SUBSTITUTION ; PHYLOGENETIC ANALYSIS ; MAXIMUM-LIKELIHOOD ; SKELETAL-MUSCLE ; GENE-EXPRESSION ; HYPOXIA ; TIBETAN ; GENOME |
| Publisher | BIOMED CENTRAL LTD |
| Funding Organization | Pilot projects ; Pilot projects ; Pilot projects ; Pilot projects ; Pilot projects ; Pilot projects ; Pilot projects ; Pilot projects ; Pilot projects ; Pilot projects ; Pilot projects ; Pilot projects ; Pilot projects ; Pilot projects ; Pilot projects ; Pilot projects |
| Citation statistics | |
| Document Type | 期刊论文 |
| Identifier | http://ir.ihb.ac.cn/handle/342005/30189 |
| Collection | 水生生物多样性与资源保护研究中心_期刊论文 水生生物多样性与资源保护研究中心_会议论文 |
| Corresponding Author | He, Shunping |
| Affiliation | 1.Chinese Acad Sci, Inst Hydrobiol, Key Lab Aquat Biodivers & Conservat, Wuhan 430072, Hubei, Peoples R China 2.Univ Chinese Acad Sci, Beijing, Peoples R China 3.Guizhou Univ, Coll Anim Sci, Guiyang 550025, Guizhou, Peoples R China |
| Recommended Citation GB/T 7714 | Kang, Jingliang,Ma, Xiuhui,He, Shunping. Evidence of high-altitude adaptation in the glyptosternoid fish, Creteuchiloglanis macropterus from the Nujiang River obtained through transcriptome analysis[J]. BMC EVOLUTIONARY BIOLOGY,2017,17:12. |
| APA | Kang, Jingliang,Ma, Xiuhui,&He, Shunping.(2017).Evidence of high-altitude adaptation in the glyptosternoid fish, Creteuchiloglanis macropterus from the Nujiang River obtained through transcriptome analysis.BMC EVOLUTIONARY BIOLOGY,17,12. |
| MLA | Kang, Jingliang,et al."Evidence of high-altitude adaptation in the glyptosternoid fish, Creteuchiloglanis macropterus from the Nujiang River obtained through transcriptome analysis".BMC EVOLUTIONARY BIOLOGY 17(2017):12. |
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