| Evolutionary patterns of RNA-based gene duplicates in Caenorhabditis nematodes coincide with their genomic features | |
| Zou,Ming1,2; Wang,Guoxiu3; He,Shunping1 | |
| Corresponding Author | He,Shunping(clad@ihb.ac.cn) |
| 2012-08-01 | |
| Source Publication | BMC Research Notes
 |
| ISSN | 1756-0500 |
| Volume | 5Issue:1 |
| Abstract | AbstractBackgroundRNA-based gene duplicates (retrocopies) played pivotal roles in many physiological processes. Nowadays, functional retrocopies have been systematically identified in several mammals, fruit flies, plants, zebrafish and other chordates, etc. However, studies about this kind of duplication in Caenorhabditis nematodes have not been reported.FindingsWe identified 43, 48, 43, 9, and 42 retrocopies, of which 6, 15, 18, 3, and 13 formed chimeric genes in C. brenneri, C. briggsae, C. elegans, C. japonica, and C. remanei, respectively. At least 5 chimeric types exist in Caenorhabditis species, of which retrocopy recruiting both N and C terminus is the commonest one. Evidences from different analyses demonstrate many retrocopies and almost all chimeric genes may be functional in these species. About half of retrocopies in each species has coordinates in other species, and we suggest that retrocopies in closely related species may be helpful in identifying retrocopies for one certain species.ConclusionsA number of retrocopies and chimeric genes exist in Caenorhabditis genomes, and some of them may be functional. The evolutionary patterns of these genes may correlate with their genomic features, such as the activity of retroelements, the high rate of mutation and deletion rate, and a large proportion of genes subject to trans-splicing. |
| Keyword | Retrocopy Chimeric gene Caenorhabditis Evolutionary pattern |
| DOI | 10.1186/1756-0500-5-398 |
| Language | 英语 |
| WOS ID | BMC:10.1186/1756-0500-5-398 |
| Publisher | BioMed Central |
| Citation statistics | |
| Document Type | 期刊论文 |
| Identifier | http://ir.ihb.ac.cn/handle/342005/28578 |
| Collection | 期刊论文 |
| Corresponding Author | He,Shunping |
| Affiliation | 1.Institute of Hydrobiology, Chinese Academy of Sciences; The key Laboratory of Aquatic Biodiversity and Conservation of Chinese Academy of Sciences 2.University of the Chinese Academy of Sciences 3.HuaZhong Normal University; Hubei Key Laboratory of Genetic Regulation and Integrative Biology |
| Recommended Citation GB/T 7714 | Zou,Ming,Wang,Guoxiu,He,Shunping. Evolutionary patterns of RNA-based gene duplicates in Caenorhabditis nematodes coincide with their genomic features[J]. BMC Research Notes,2012,5(1). |
| APA | Zou,Ming,Wang,Guoxiu,&He,Shunping.(2012).Evolutionary patterns of RNA-based gene duplicates in Caenorhabditis nematodes coincide with their genomic features.BMC Research Notes,5(1). |
| MLA | Zou,Ming,et al."Evolutionary patterns of RNA-based gene duplicates in Caenorhabditis nematodes coincide with their genomic features".BMC Research Notes 5.1(2012). |
| Files in This Item: | There are no files associated with this item. | |||||
Items in the repository are protected by copyright, with all rights reserved, unless otherwise indicated.
Edit Comment