IHB OpenIR  > 水环境工程研究中心
Microplastic Size-Dependent Toxicity, Oxidative Stress Induction, and p-JNK and p-p38 Activation in the Monogonont Rotifer (Brachionus koreanus)
Jeong, Chang-Bum1,2; Won, Eun-Ji1,3; Kang, Hye-Min1; Lee, Min-Chul1; Hwang, Dae-Sik1; Hwang, Un-Ki4; Zhou, Bingsheng5; Souissi, Sami6; Lee, Su-Jae7; Lee, Jae-Seong1
2016-08-16
Source PublicationENVIRONMENTAL SCIENCE & TECHNOLOGY
ISSN0013-936X
Volume50Issue:16Pages:8849-8857
AbstractIn this study, we evaluated accumulation and adverse effects of ingestion of microplastics in the monogonont rotifer (Brachionus koreanus). The dependence of microplastic toxicity on particle size-was investigated by measuring several in vivo end points and studying the ingestion and egestion using 0.05-, 0.5-, and 6-mu m nonfunctionalized polystyrene microbeads. To identify the defense mechanisms activated in response to microplastic exposure, the activities of several antioxidant-related enzymes and the phosphorylation status of mitogen-activated protein kinases (MAPKs) were determined. Exposure to polystyrene microbeads of all sizes led to significant size dependent effects, including reduced groWth rate, reduced fecundity, decreased lifespan and longer reproduction time. Rotifers exposed to 6-mu m fluorescently labeled microbeads exhibited almost no fluorescence after 24 h, while rotifers exposed to 0.05- and 0.5-mu m fluoresceatly labeled inicrobeads displayed fluorescence until 48 h, suggesting that 6-mu m microbeads are more effectively egested from B. koreanus than 0.05- or 0.5-mu m microbeads. This observation provides a potential explanation for our findings that microbead toxicity was size dependent and smaller microbeads were more toxic. In vitro tests revealed that antioxidant-related enzymes and MAPK signaling pathways were significantly activated in response to microplastic exposure in a size-dependent manner.
SubtypeArticle
DOI10.1021/acs.est.6b01441
WOS HeadingsScience & Technology ; Technology ; Life Sciences & Biomedicine
Indexed BySCI
Funding OrganizationDevelopment of Techniques for Assessment and Management of Hazardous Chemicals in the Marine Environment of the Ministry of Oceans and Fisheries, Kore(20150342) ; Development of Techniques for Assessment and Management of Hazardous Chemicals in the Marine Environment of the Ministry of Oceans and Fisheries, Kore(20150342) ; Korea-Polar Ocean Development: K-POD of the Ministry of Oceans and Fisheries, Korea(PM15050) ; Korea-Polar Ocean Development: K-POD of the Ministry of Oceans and Fisheries, Korea(PM15050) ; Development of Techniques for Assessment and Management of Hazardous Chemicals in the Marine Environment of the Ministry of Oceans and Fisheries, Kore(20150342) ; Development of Techniques for Assessment and Management of Hazardous Chemicals in the Marine Environment of the Ministry of Oceans and Fisheries, Kore(20150342) ; Korea-Polar Ocean Development: K-POD of the Ministry of Oceans and Fisheries, Korea(PM15050) ; Korea-Polar Ocean Development: K-POD of the Ministry of Oceans and Fisheries, Korea(PM15050)
Language英语
WOS Research AreaEngineering ; Environmental Sciences & Ecology
WOS SubjectEngineering, Environmental ; Environmental Sciences
WOS KeywordCOPEPOD TIGRIOPUS-JAPONICUS ; MYTILUS-EDULIS L. ; MARINE-ENVIRONMENT ; SIGNALING PATHWAY ; GROWTH-RETARDATION ; NANOPARTICLES ; FECUNDITY ; MUSSEL ; CELLS ; ECOTOXICOLOGY
WOS IDWOS:000381654600048
Funding OrganizationDevelopment of Techniques for Assessment and Management of Hazardous Chemicals in the Marine Environment of the Ministry of Oceans and Fisheries, Kore(20150342) ; Development of Techniques for Assessment and Management of Hazardous Chemicals in the Marine Environment of the Ministry of Oceans and Fisheries, Kore(20150342) ; Korea-Polar Ocean Development: K-POD of the Ministry of Oceans and Fisheries, Korea(PM15050) ; Korea-Polar Ocean Development: K-POD of the Ministry of Oceans and Fisheries, Korea(PM15050) ; Development of Techniques for Assessment and Management of Hazardous Chemicals in the Marine Environment of the Ministry of Oceans and Fisheries, Kore(20150342) ; Development of Techniques for Assessment and Management of Hazardous Chemicals in the Marine Environment of the Ministry of Oceans and Fisheries, Kore(20150342) ; Korea-Polar Ocean Development: K-POD of the Ministry of Oceans and Fisheries, Korea(PM15050) ; Korea-Polar Ocean Development: K-POD of the Ministry of Oceans and Fisheries, Korea(PM15050)
Citation statistics
Document Type期刊论文
Identifierhttp://ir.ihb.ac.cn/handle/342005/28336
Collection水环境工程研究中心
Affiliation1.Sungkyunkwan Univ, Coll Sci, Dept Biol Sci, Suwon 16419, South Korea
2.Hanyang Univ, Dept Chem, Coll Nat Sci, Seoul 04763, South Korea
3.Korea Inst Ocean Sci & Technol, Marine Chem & Geochem Res Ctr, Ansan 15627, South Korea
4.Natl Fisheries Res & Dev Inst, Marine Ecol Risk Assessment Ctr, West Sea Fisheries Res Inst, Inchon 46083, South Korea
5.Chinese Acad Sci, Inst Hydrobiol, State Key Lab Freshwater Ecol & Biotechnol, Wuhan 430072, Peoples R China
6.Univ Littoral Cote dOpale, LOG, Univ Lille, CNRS,UMR 8187, F-62930 Wimereux, France
7.Hanyang Univ, Dept Life Sci, Coll Nat Sci, Seoul 04763, South Korea
Recommended Citation
GB/T 7714
Jeong, Chang-Bum,Won, Eun-Ji,Kang, Hye-Min,et al. Microplastic Size-Dependent Toxicity, Oxidative Stress Induction, and p-JNK and p-p38 Activation in the Monogonont Rotifer (Brachionus koreanus)[J]. ENVIRONMENTAL SCIENCE & TECHNOLOGY,2016,50(16):8849-8857.
APA Jeong, Chang-Bum.,Won, Eun-Ji.,Kang, Hye-Min.,Lee, Min-Chul.,Hwang, Dae-Sik.,...&Lee, Jae-Seong.(2016).Microplastic Size-Dependent Toxicity, Oxidative Stress Induction, and p-JNK and p-p38 Activation in the Monogonont Rotifer (Brachionus koreanus).ENVIRONMENTAL SCIENCE & TECHNOLOGY,50(16),8849-8857.
MLA Jeong, Chang-Bum,et al."Microplastic Size-Dependent Toxicity, Oxidative Stress Induction, and p-JNK and p-p38 Activation in the Monogonont Rotifer (Brachionus koreanus)".ENVIRONMENTAL SCIENCE & TECHNOLOGY 50.16(2016):8849-8857.
Files in This Item:
File Name/Size DocType Version Access License
acs.est.6b01441.pdf(4386KB) 开放获取--View Application Full Text
Related Services
Recommend this item
Bookmark
Usage statistics
Export to Endnote
Google Scholar
Similar articles in Google Scholar
[Jeong, Chang-Bum]'s Articles
[Won, Eun-Ji]'s Articles
[Kang, Hye-Min]'s Articles
Baidu academic
Similar articles in Baidu academic
[Jeong, Chang-Bum]'s Articles
[Won, Eun-Ji]'s Articles
[Kang, Hye-Min]'s Articles
Bing Scholar
Similar articles in Bing Scholar
[Jeong, Chang-Bum]'s Articles
[Won, Eun-Ji]'s Articles
[Kang, Hye-Min]'s Articles
Terms of Use
No data!
Social Bookmark/Share
File name: acs.est.6b01441.pdf
Format: Adobe PDF
This file does not support browsing at this time
All comments (0)
No comment.
 

Items in the repository are protected by copyright, with all rights reserved, unless otherwise indicated.