IHB OpenIR  > 水生生物分子与细胞生物学研究中心
Sodium butyrate supplementation in high-soybean meal diets for turbot (Scophthalmus maximus L.): Effects on inflammatory status, mucosal barriers and microbiota in the intestine
Liu, Yang1,2; Chen, Zhichu1,2; Dai, Jihong1,2; Yang, Pei1,2; Xu, Weiqi1,2; Ai, Qinghui1,2; Zhang, Wenbing1,2; Zhang, Yongan4; Zhang, Yanjiao1,2,3; Mai, Kangsen1,2,3
Corresponding AuthorZhang, Yanjiao(yanjiaozhang@ouc.edu.cn)
2019-05-01
Source PublicationFISH & SHELLFISH IMMUNOLOGY
ISSN1050-4648
Volume88Pages:65-75
AbstractA 12-week feeding trial was conducted to evaluate the effects of dietary sodium butyrate (NaBT) on the intestinal health of juvenile turbot (Scophthalmus maximus L.), in terms of inflammatory status, mucosal barriers and microbiota. Three isonitrogenous and isolipidic practical diets were used: (1) fish meal based group (FM); (2) soybean meal group (SBM), soy protein replacing 40% fish meal protein in FM; (3) NaBT group, 0.2% NaBT supplemented in SBM. Each diet was fed to triplicate tanks (30 fish in each tank). The current results showed that 0.2% dietary NaBT improved the growth performance of fish and alleviated the enteropathy, increasing the absorptive surface and mitigating the infiltration of mixed leukocytes in lamina propria. Fish fed the NaBT diet presented increased activities of intestinal brush border enzyme and similar nutrient digestibility with the FM group. Compared to SBM, the inclusion of 0.2% NaBT in diet significantly up-regulated the intestinal gene expression of tight junction proteins and down-regulated the gene expression of TNF-alpha and NF-kappa B. The gut microbial communities of the NaBT group were closer to the FM group than to the SBM group, in terms of PCoA, UPGMA and Heatmap analyses based on weighted Unifrac distance. The relative abundance of several dominant bacteria at the phylum (Proteobacteria, Bacteroldetes, Deinococcus-Thermus and Actinobacteria) and genus level (Thermos, Acinetobacter, Bacteroides and Silanimonas) were altered by dietary NaBT. In conclusion, dietary NaBT had positive roles in protecting the intestinal health of turbot from the impairment of soybean meal.
KeywordSodium butyrate Soybean meal Enteropathy Intestinal mucosal barrier Intestinal microbiota Turbot
DOI10.1016/j.fsi.2019.02.064
Funding OrganizationNational Basic Research Program (973 program) ; National Basic Research Program (973 program) ; National Basic Research Program (973 program) ; National Basic Research Program (973 program) ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; China Agriculture Researches System ; China Agriculture Researches System ; China Agriculture Researches System ; China Agriculture Researches System ; National Basic Research Program (973 program) ; National Basic Research Program (973 program) ; National Basic Research Program (973 program) ; National Basic Research Program (973 program) ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; China Agriculture Researches System ; China Agriculture Researches System ; China Agriculture Researches System ; China Agriculture Researches System ; National Basic Research Program (973 program) ; National Basic Research Program (973 program) ; National Basic Research Program (973 program) ; National Basic Research Program (973 program) ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; China Agriculture Researches System ; China Agriculture Researches System ; China Agriculture Researches System ; China Agriculture Researches System ; National Basic Research Program (973 program) ; National Basic Research Program (973 program) ; National Basic Research Program (973 program) ; National Basic Research Program (973 program) ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; China Agriculture Researches System ; China Agriculture Researches System ; China Agriculture Researches System ; China Agriculture Researches System
Indexed BySCI ; SCI
Language英语
Funding ProjectNational Basic Research Program (973 program)[2014CB138601] ; National Natural Science Foundation of China[41576137] ; National Natural Science Foundation of China[31202006] ; China Agriculture Researches System[CARS 47-G10]
WOS Research AreaFisheries ; Immunology ; Marine & Freshwater Biology ; Veterinary Sciences
WOS SubjectFisheries ; Immunology ; Marine & Freshwater Biology ; Veterinary Sciences
WOS IDWOS:000465060500008
WOS KeywordCHAIN FATTY-ACIDS ; NF-KAPPA-B ; GROWTH-PERFORMANCE ; PARACELLULAR PERMEABILITY ; IMMUNE-RESPONSE ; TIGHT JUNCTIONS ; COLONIC-MUCOSA ; ZEBRAFISH ; BACTERIA ; COLITIS
PublisherACADEMIC PRESS LTD- ELSEVIER SCIENCE LTD
Funding OrganizationNational Basic Research Program (973 program) ; National Basic Research Program (973 program) ; National Basic Research Program (973 program) ; National Basic Research Program (973 program) ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; China Agriculture Researches System ; China Agriculture Researches System ; China Agriculture Researches System ; China Agriculture Researches System ; National Basic Research Program (973 program) ; National Basic Research Program (973 program) ; National Basic Research Program (973 program) ; National Basic Research Program (973 program) ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; China Agriculture Researches System ; China Agriculture Researches System ; China Agriculture Researches System ; China Agriculture Researches System ; National Basic Research Program (973 program) ; National Basic Research Program (973 program) ; National Basic Research Program (973 program) ; National Basic Research Program (973 program) ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; China Agriculture Researches System ; China Agriculture Researches System ; China Agriculture Researches System ; China Agriculture Researches System ; National Basic Research Program (973 program) ; National Basic Research Program (973 program) ; National Basic Research Program (973 program) ; National Basic Research Program (973 program) ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; China Agriculture Researches System ; China Agriculture Researches System ; China Agriculture Researches System ; China Agriculture Researches System
Citation statistics
Cited Times:1[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.ihb.ac.cn/handle/342005/27738
Collection水生生物分子与细胞生物学研究中心
Corresponding AuthorZhang, Yanjiao
Affiliation1.Ocean Univ China, Key Lab Aquaculture Nutr & Feed, Minist Agr, Qingdao 266003, Shandong, Peoples R China
2.Ocean Univ China, Key Lab Mariculture, Minist Educ, Qingdao 266003, Shandong, Peoples R China
3.Qingdao Natl Lab Marine Sci & Technol, Lab Marine Fisheries Sci & Food Prod Proc, Qingdao 266237, Shandong, Peoples R China
4.Chinese Acad Sci, Inst Hydrobiol, Wuhan 430072, Hubei, Peoples R China
Recommended Citation
GB/T 7714
Liu, Yang,Chen, Zhichu,Dai, Jihong,et al. Sodium butyrate supplementation in high-soybean meal diets for turbot (Scophthalmus maximus L.): Effects on inflammatory status, mucosal barriers and microbiota in the intestine[J]. FISH & SHELLFISH IMMUNOLOGY,2019,88:65-75.
APA Liu, Yang.,Chen, Zhichu.,Dai, Jihong.,Yang, Pei.,Xu, Weiqi.,...&Mai, Kangsen.(2019).Sodium butyrate supplementation in high-soybean meal diets for turbot (Scophthalmus maximus L.): Effects on inflammatory status, mucosal barriers and microbiota in the intestine.FISH & SHELLFISH IMMUNOLOGY,88,65-75.
MLA Liu, Yang,et al."Sodium butyrate supplementation in high-soybean meal diets for turbot (Scophthalmus maximus L.): Effects on inflammatory status, mucosal barriers and microbiota in the intestine".FISH & SHELLFISH IMMUNOLOGY 88(2019):65-75.
Files in This Item:
There are no files associated with this item.
Related Services
Recommend this item
Bookmark
Usage statistics
Export to Endnote
Google Scholar
Similar articles in Google Scholar
[Liu, Yang]'s Articles
[Chen, Zhichu]'s Articles
[Dai, Jihong]'s Articles
Baidu academic
Similar articles in Baidu academic
[Liu, Yang]'s Articles
[Chen, Zhichu]'s Articles
[Dai, Jihong]'s Articles
Bing Scholar
Similar articles in Bing Scholar
[Liu, Yang]'s Articles
[Chen, Zhichu]'s Articles
[Dai, Jihong]'s Articles
Terms of Use
No data!
Social Bookmark/Share
All comments (0)
No comment.
 

Items in the repository are protected by copyright, with all rights reserved, unless otherwise indicated.