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题名: Neuroendocrine regulation of somatic growth in fishes
作者: Dai XiangYan1, 2; Zhang Wei1, 2; Zhuo ZiJian1, 2; He JiangYan1; Yin Zhan1
通讯作者: Yin, Z (reprint author), Chinese Acad Sci, Inst Hydrobiol, Key Lab Aquat Biodivers & Conservat, Wuhan 430072, Peoples R China.
关键词: somatic growth ; endocrine regulation ; fish
刊名: SCIENCE CHINA-LIFE SCIENCES
发表日期: 2015-02-01
DOI: 10.1007/s11427-015-4805-8
卷: 58, 期:2, 页:137-147
收录类别: SCI
文章类型: Review
部门归属: [Dai XiangYan ; Zhang Wei ; Zhuo ZiJian ; He JiangYan ; Yin Zhan] Chinese Acad Sci, Inst Hydrobiol, Key Lab Aquat Biodivers & Conservat, Wuhan 430072, Peoples R China ; [Dai XiangYan ; Zhang Wei ; Zhuo ZiJian] Univ Chinese Acad Sci, Beijing 100049, Peoples R China
WOS标题词: Science & Technology ; Life Sciences & Biomedicine
类目[WOS]: Biology
研究领域[WOS]: Life Sciences & Biomedicine - Other Topics
英文摘要: Growth is a polygenic trait that is under the influence of multiple physiological pathways regulating energy metabolism and muscle growth. Among the possible growth-regulating pathways in vertebrates, components of the somatotropic axis are thought to have the greatest influence. There is growing body of literature focusing on the somatotropic axis and its role regulating growth in fish. This includes research into growth hormone, upstream hypothalamic hormones, insulin-like growth factors, and downstream signaling molecules. Many of these signals have both somatic effects stimulating the growth of tissues and metabolic effects that play a role in nutrient metabolism. Signals of other endocrine axes exhibit profound effects on the function of the somatotropic axis in vivo. In this review we highlight recent advances in our understanding of the teleost fish endocrine somatotropic axis, including emerging research using genetic modified models. These studies have revealed new aspects and challenges associated with regulation of the important steps of somatic growth.
关键词[WOS]: CYCLASE-ACTIVATING POLYPEPTIDE ; HORMONE-RELEASING-HORMONE ; TROUT ONCORHYNCHUS-MYKISS ; GROUPER EPINEPHELUS-COIOIDES ; TACHYKININ NK2 RECEPTORS ; IMMATURE RAINBOW-TROUT ; GERM-CELL MIGRATION ; I MESSENGER-RNA ; ADENYLATE-CYCLASE ; GENE-EXPRESSION
语种: 英语
WOS记录号: WOS:000349407000003
ISSN号: 1674-7305
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.ihb.ac.cn/handle/342005/23988
Appears in Collections:水生生物分子与细胞生物学研究中心_期刊论文

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作者单位: 1.Chinese Acad Sci, Inst Hydrobiol, Key Lab Aquat Biodivers & Conservat, Wuhan 430072, Peoples R China
2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
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