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The impact of long term exposure to phthalic acid esters on reproduction in Chinese rare minnow (Gobiocypris rarus)
Guo, Yongyong1; Yang, Yuanjin2; Gao, Yong2; Wang, Xianfeng1; Zhou, Bingsheng1; Zhou, BS (reprint author), Chinese Acad Sci, Inst Hydrobiol, Wuhan 430072, Peoples R China.
2015-08-01
Source PublicationENVIRONMENTAL POLLUTION
ISSN0269-7491
Volume203Pages:130-136
AbstractThe environmental risk of phthalic acid esters (PAEs) is of great concern. We investigated the reproductive impairment of di-(2-ethylhexyl)-phthalate (DEHP) on Chinese rare minnow, an endemic fish inhabiting the upper streams of the Yangtze River. Chinese rare minnow larvae were exposed to environmentally relevant concentrations of DEHP (0, 4.2, 13.3, and 40.8 mu g/L) for 6 months. Plasma testosterone and 17 beta-estradiol levels decreased in females, accompanied by downregulation of cyp19a and cyp17 gene transcription in ovary. Increases in plasma testosterone concentration were observed in males, accompanied by downregulation of cyp19a gene transcription in testes. Hepatic VTG gene transcription was upregulated in males and females. Exposure to DEHP reduced egg production and inhibited oocyte maturation in females and retarded spermiation in males. Decreased egg protein content was measured in F1 embryos. These results indicate that long-term exposure to low concentrations of DEHP (13.3 mu g/L) causes endocrine disruption and impairs fish reproduction. (C) 2015 Elsevier Ltd. All rights reserved.
SubtypeArticle
KeywordDi-(2-ethylhexyl)-phthalate Endocrine Disruption Reproductive Toxicity Environmental Risk Chinese Rare Minnow
Department[Guo, Yongyong ; Wang, Xianfeng ; Zhou, Bingsheng] Chinese Acad Sci, Inst Hydrobiol, State Key Lab Freshwater Ecol & Biotechnol, Wuhan 430072, Peoples R China ; [Yang, Yuanjin ; Gao, Yong] China Three Gorges Corp, Inst Chinese Sturgeon Res, Yichang, Hubei, Peoples R China
DOI10.1016/j.envpol.2015.04.005
WOS HeadingsScience & Technology ; Life Sciences & Biomedicine
Indexed BySCI
Language英语
WOS Research AreaEnvironmental Sciences & Ecology
WOS SubjectEnvironmental Sciences
WOS IDWOS:000356643000015
WOS KeywordTHREE-GORGES DAM ; YANGTZE-RIVER ; ENDOCRINE DISRUPTION ; GENE-EXPRESSION ; FATHEAD MINNOW ; SURFACE-WATER ; DANIO-RERIO ; IN-VITRO ; CONTAMINATION ; TESTOSTERONE
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Cited Times:13[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.ihb.ac.cn/handle/342005/23932
Collection水环境工程研究中心_期刊论文
Corresponding AuthorZhou, BS (reprint author), Chinese Acad Sci, Inst Hydrobiol, Wuhan 430072, Peoples R China.
Affiliation1.Chinese Acad Sci, Inst Hydrobiol, State Key Lab Freshwater Ecol & Biotechnol, Wuhan 430072, Peoples R China
2.China Three Gorges Corp, Inst Chinese Sturgeon Res, Yichang, Hubei, Peoples R China
Recommended Citation
GB/T 7714
Guo, Yongyong,Yang, Yuanjin,Gao, Yong,et al. The impact of long term exposure to phthalic acid esters on reproduction in Chinese rare minnow (Gobiocypris rarus)[J]. ENVIRONMENTAL POLLUTION,2015,203:130-136.
APA Guo, Yongyong,Yang, Yuanjin,Gao, Yong,Wang, Xianfeng,Zhou, Bingsheng,&Zhou, BS .(2015).The impact of long term exposure to phthalic acid esters on reproduction in Chinese rare minnow (Gobiocypris rarus).ENVIRONMENTAL POLLUTION,203,130-136.
MLA Guo, Yongyong,et al."The impact of long term exposure to phthalic acid esters on reproduction in Chinese rare minnow (Gobiocypris rarus)".ENVIRONMENTAL POLLUTION 203(2015):130-136.
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