| The impact of long term exposure to phthalic acid esters on reproduction in Chinese rare minnow (Gobiocypris rarus) | |
| Guo, Yongyong1; Yang, Yuanjin2; Gao, Yong2; Wang, Xianfeng1; Zhou, Bingsheng1; Zhou, BS (reprint author), Chinese Acad Sci, Inst Hydrobiol, Wuhan 430072, Peoples R China. | |
| 2015-08-01 | |
| Source Publication | ENVIRONMENTAL POLLUTION
 |
| ISSN | 0269-7491 |
| Volume | 203Pages:130-136 |
| Abstract | The environmental risk of phthalic acid esters (PAEs) is of great concern. We investigated the reproductive impairment of di-(2-ethylhexyl)-phthalate (DEHP) on Chinese rare minnow, an endemic fish inhabiting the upper streams of the Yangtze River. Chinese rare minnow larvae were exposed to environmentally relevant concentrations of DEHP (0, 4.2, 13.3, and 40.8 mu g/L) for 6 months. Plasma testosterone and 17 beta-estradiol levels decreased in females, accompanied by downregulation of cyp19a and cyp17 gene transcription in ovary. Increases in plasma testosterone concentration were observed in males, accompanied by downregulation of cyp19a gene transcription in testes. Hepatic VTG gene transcription was upregulated in males and females. Exposure to DEHP reduced egg production and inhibited oocyte maturation in females and retarded spermiation in males. Decreased egg protein content was measured in F1 embryos. These results indicate that long-term exposure to low concentrations of DEHP (13.3 mu g/L) causes endocrine disruption and impairs fish reproduction. (C) 2015 Elsevier Ltd. All rights reserved. |
| Subtype | Article |
| Keyword | Di-(2-ethylhexyl)-phthalate Endocrine Disruption Reproductive Toxicity Environmental Risk Chinese Rare Minnow |
| Department | [Guo, Yongyong ; Wang, Xianfeng ; Zhou, Bingsheng] Chinese Acad Sci, Inst Hydrobiol, State Key Lab Freshwater Ecol & Biotechnol, Wuhan 430072, Peoples R China ; [Yang, Yuanjin ; Gao, Yong] China Three Gorges Corp, Inst Chinese Sturgeon Res, Yichang, Hubei, Peoples R China |
| DOI | 10.1016/j.envpol.2015.04.005 |
| WOS Headings | Science & Technology ; Life Sciences & Biomedicine |
| Indexed By | SCI |
| Language | 英语 |
| WOS Research Area | Environmental Sciences & Ecology |
| WOS Subject | Environmental Sciences |
| WOS ID | WOS:000356643000015 |
| WOS Keyword | THREE-GORGES DAM ; YANGTZE-RIVER ; ENDOCRINE DISRUPTION ; GENE-EXPRESSION ; FATHEAD MINNOW ; SURFACE-WATER ; DANIO-RERIO ; IN-VITRO ; CONTAMINATION ; TESTOSTERONE |
| Citation statistics | |
| Document Type | 期刊论文 |
| Identifier | http://ir.ihb.ac.cn/handle/342005/23932 |
| Collection | 水环境工程研究中心_期刊论文 |
| Corresponding Author | Zhou, BS (reprint author), Chinese Acad Sci, Inst Hydrobiol, Wuhan 430072, Peoples R China. |
| Affiliation | 1.Chinese Acad Sci, Inst Hydrobiol, State Key Lab Freshwater Ecol & Biotechnol, Wuhan 430072, Peoples R China 2.China Three Gorges Corp, Inst Chinese Sturgeon Res, Yichang, Hubei, Peoples R China |
| Recommended Citation GB/T 7714 | Guo, Yongyong,Yang, Yuanjin,Gao, Yong,et al. The impact of long term exposure to phthalic acid esters on reproduction in Chinese rare minnow (Gobiocypris rarus)[J]. ENVIRONMENTAL POLLUTION,2015,203:130-136. |
| APA | Guo, Yongyong,Yang, Yuanjin,Gao, Yong,Wang, Xianfeng,Zhou, Bingsheng,&Zhou, BS .(2015).The impact of long term exposure to phthalic acid esters on reproduction in Chinese rare minnow (Gobiocypris rarus).ENVIRONMENTAL POLLUTION,203,130-136. |
| MLA | Guo, Yongyong,et al."The impact of long term exposure to phthalic acid esters on reproduction in Chinese rare minnow (Gobiocypris rarus)".ENVIRONMENTAL POLLUTION 203(2015):130-136. |
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