中国科学院水生生物研究所机构知识库
Advanced  
IHB OpenIR  > 鱼类生物学及渔业生物技术研究中心  > 期刊论文
题名: Molecular characterization and expression of three preprosomatostatin genes and their association with growth in common carp (Cyprinus carpio)
作者: Feng, Xiu1, 2; Yu, Xiaomu1; Pang, Meixia1, 2; Liu, Haiyang1, 2; Tong, Jingou1
通讯作者: Tong, JO (reprint author), Chinese Acad Sci, Inst Hydrol, State Key Lab Freshwater Ecol & Biotechnol, Wuhan 430072, Peoples R China.
关键词: Cyprinus carpio ; Preprosomatostatin ; Molecular characterization ; Expression pattern ; Genetic association
刊名: COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY
发表日期: 2015-04-01
DOI: 10.1016/j.cbpb.2014.12.001
卷: 182, 页:37-46
收录类别: SCI
文章类型: Article
部门归属: [Feng, Xiu ; Yu, Xiaomu ; Pang, Meixia ; Liu, Haiyang ; Tong, Jingou] Chinese Acad Sci, Inst Hydrol, State Key Lab Freshwater Ecol & Biotechnol, Wuhan 430072, Peoples R China ; [Feng, Xiu ; Pang, Meixia ; Liu, Haiyang] Univ Chinese Acad Sci, Beijing 100049, Peoples R China
WOS标题词: Science & Technology ; Life Sciences & Biomedicine
类目[WOS]: Biochemistry & Molecular Biology ; Zoology
研究领域[WOS]: Biochemistry & Molecular Biology ; Zoology
英文摘要: Somatostatins (SSs) are a structurally diverse family of peptides that play important roles in the regulation of growth, development and metabolism in vertebrates. In this study, three preprosomatostatin genes (PSSs) in the common carp, Cyprinus carpio (Cc) were identified and characterized. Based on cloned sequences and genome BLAST, six isoforms of the PSS gene in C. carpio (CcPSS) were identified and included CcPSS1a and CcPSS1b, CcPSS2a and CcPSS2b, and finally, CcPSS3a and CcPSS3b. The open reading frames (ORF) of CcPSS1a, CcPSS2a and CcPSS3a consist of 345, 336 and 363 nucleotides. During embryonic development, the expressions of CcPSS2 and CcPSS3 were first observed at the stage of optic vesicle, and CcPSS1 mRNA was initially detected at the stage of muscular effect. The highest mRNA levels of CcPSS1, CcPSS2 and CcPSS3 were observed at 1-day post-hatch (dph), 2-dph and the stage of heart beating, respectively. In the adult brain, the distributions of three CcPSS mRNAs were differential but overlapping in the hypothalamus, telencephalon and medulla oblongata. For peripheral tissues, all three CcPSS mRNAs were detected in the mid-intestine, and CcPSS1 and CcPSS3 mRNAs were also expressed in the liver. Owing to the importance of somatostatins on regulating growth, functional mutations of CcPSSs were identified in a C carpio population. A total of 23 polymorphic sites were detected in CcPSS1a and CcPSS3a. Of them, two SNPs (CcPSS1a-g.922C>T, and CcPSS3a-g.1125C>A) were significantly associated with growth traits, indicating their potential applications in gene (marker)-assisted selective breeding in C. carpio. (C) 2014 Elsevier Inc All rights reserved.
关键词[WOS]: QUANTITATIVE TRAIT LOCI ; MESSENGER-RNAS ; SOMATOSTATIN PRECURSORS ; EMBRYONIC-DEVELOPMENT ; POLYGENIC EXPRESSION ; CARCASS COMPOSITION ; PROSOMATOSTATIN-I ; HORMONE RECEPTOR ; FISH ; CORTISTATIN
语种: 英语
WOS记录号: WOS:000352746300005
ISSN号: 1096-4959
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.ihb.ac.cn/handle/342005/23897
Appears in Collections:鱼类生物学及渔业生物技术研究中心_期刊论文

Files in This Item:
File Name/ File Size Content Type Version Access License
Molecular characterization and expression of three preprosomatostatin genes and their association with growth in common carp (Cyprinus carpio).pdf(504KB)----开放获取View 联系获取全文

作者单位: 1.Chinese Acad Sci, Inst Hydrol, State Key Lab Freshwater Ecol & Biotechnol, Wuhan 430072, Peoples R China
2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
Service
Recommend this item
Sava as my favorate item
Show this item's statistics
Export Endnote File
Google Scholar
Similar articles in Google Scholar
[Feng, Xiu]'s Articles
[Yu, Xiaomu]'s Articles
[Pang, Meixia]'s Articles
CSDL cross search
Similar articles in CSDL Cross Search
[Feng, Xiu]‘s Articles
[Yu, Xiaomu]‘s Articles
[Pang, Meixia]‘s Articles
Related Copyright Policies
Null
Social Bookmarking
Add to CiteULike Add to Connotea Add to Del.icio.us Add to Digg Add to Reddit
文件名: Molecular characterization and expression of three preprosomatostatin genes and their association with growth in common carp (Cyprinus carpio).pdf
格式: Adobe PDF
所有评论 (0)
暂无评论
 
评注功能仅针对注册用户开放,请您登录
您对该条目有什么异议,请填写以下表单,管理员会尽快联系您。
内 容:
Email:  *
单位:
验证码:   刷新
您在IR的使用过程中有什么好的想法或者建议可以反馈给我们。
标 题:
 *
内 容:
Email:  *
验证码:   刷新

Items in IR are protected by copyright, with all rights reserved, unless otherwise indicated.

 

 

Valid XHTML 1.0!
Copyright © 2007-2016  中国科学院水生生物研究所 - Feedback
Powered by CSpace