IHB OpenIR  > 水环境工程研究中心  > 期刊论文
Combined chemical and toxicological long-term monitoring for AhR agonists with SPMD-based virtual organisms in drinking water Danjiangkou Reservoir, China
Wang, Jingxian1,3,4,5; Song, Guoqiang2; Li, Aimin2; Henkelmann, Bernhard3; Pfister, Gerd3; Tong, Anthony Z.5; Schramm, Karl-Werner3,4
2014-08-01
Source PublicationCHEMOSPHERE
ISSN0045-6535
Volume108Pages:306-313
AbstractSPMD-based virtual organisms (VOs) were employed for time-integrating, long-term sampling combined biological and chemical analyses for exposure assessment of hydrophobic organic pollutants (HOPs) in a drinking water reservoir, China. The SPMDs were deployed at four and five sites in the Danjiangkou (DJK) reservoir over two periods of 26 and 31 d to sequester the hydrophobic contaminants in water. The chosen bioassay response for the extracts of the SPMDs, the induction of 7-ethoxyresorufin-o-deethylase (EROD) was assayed using a rat hepatoma cell line (H4IIE). The known aryl hydrocarbon receptor (AhR) agonists PAHs and PCBs were analyzed by HRGC/HRMS instrument. The cause-effect relationship between the observed AhR activities and chemical concentrations of detected AhR agonists was examined. The results show that the extracts from the SPMD samples could induce AhR activity significantly, whereas the chemically derived 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) equivalent (TEQ(cal)) was not correlated with the bioassay-derived TCDD equivalent (TEQ(bio)). The known AhR agonists could only account for 2-10% of the observed AhR responses among which the contribution of PCBs could almost be neglected. Unidentified AhR-active compounds represented a greater proportion of the TCDD equivalent (TCDD-EQ) in SPMD samples from DJK. Based on the first assessment, the VO followed by the combination of chemical and biological analyses emerges as a resource efficient water monitoring device in ecotoxicological assessment for toxicologically relevant compounds which are readily available for uptake by resident aquatic biota in drinking water resources. (C) 2014 Elsevier Ltd. All rights reserved.
SubtypeArticle
KeywordHydrophobic Organic Pollutants (Hops) Ahr Activity Virtual Organisms (Vos) Semipermeable Membrane Devices (Spmds) Drinking Water Danjiangkou Reservoir (Djk)
DOI10.1016/j.chemosphere.2014.01.056
WOS HeadingsScience & Technology ; Life Sciences & Biomedicine
Indexed BySCI
Language英语
WOS Research AreaEnvironmental Sciences & Ecology
WOS SubjectEnvironmental Sciences
WOS IDWOS:000337881600040
WOS KeywordPOLYCYCLIC AROMATIC-HYDROCARBONS ; DIOXIN-LIKE COMPOUNDS ; TOXIC EQUIVALENCY FACTORS ; MEMBRANE DEVICES SPMDS ; ENVIRONMENTAL-SAMPLES ; RECEPTOR AGONISTS ; UPTAKE KINETICS ; PAHS ; IDENTIFICATION ; RIVER
Citation statistics
Document Type期刊论文
Identifierhttp://ir.ihb.ac.cn/handle/342005/20371
Collection水环境工程研究中心_期刊论文
Affiliation1.Chinese Acad Sci, State Key Lab Freshwater Ecol & Biotechnol, Inst Hydrobiol, Wuhan 430072, Peoples R China
2.Hubei Environm Monitoring Ctr StN, Wuhan 430072, Peoples R China
3.German Res Ctr Environm Hlth GmbH, Helmholtz Ctr Munich, Mol EXpos MEX, D-85764 Neuherberg, Germany
4.TIJM, Wissensch Zentrum Weihenstephan Fuer Ernaehrun &, Dept fuer Biowissensch Grundlagen, D-85350 Freising Weihenstephan, Germany
5.Acadia Univ, Dept Chem, Wolfville, NS B4P 2R6, Canada
Recommended Citation
GB/T 7714
Wang, Jingxian,Song, Guoqiang,Li, Aimin,et al. Combined chemical and toxicological long-term monitoring for AhR agonists with SPMD-based virtual organisms in drinking water Danjiangkou Reservoir, China[J]. CHEMOSPHERE,2014,108:306-313.
APA Wang, Jingxian.,Song, Guoqiang.,Li, Aimin.,Henkelmann, Bernhard.,Pfister, Gerd.,...&Schramm, Karl-Werner.(2014).Combined chemical and toxicological long-term monitoring for AhR agonists with SPMD-based virtual organisms in drinking water Danjiangkou Reservoir, China.CHEMOSPHERE,108,306-313.
MLA Wang, Jingxian,et al."Combined chemical and toxicological long-term monitoring for AhR agonists with SPMD-based virtual organisms in drinking water Danjiangkou Reservoir, China".CHEMOSPHERE 108(2014):306-313.
Files in This Item: Download All
File Name/Size DocType Version Access License
Combined chemical an(726KB) 开放获取CC BY-NC-SAView Download
Related Services
Recommend this item
Bookmark
Usage statistics
Export to Endnote
Google Scholar
Similar articles in Google Scholar
[Wang, Jingxian]'s Articles
[Song, Guoqiang]'s Articles
[Li, Aimin]'s Articles
Baidu academic
Similar articles in Baidu academic
[Wang, Jingxian]'s Articles
[Song, Guoqiang]'s Articles
[Li, Aimin]'s Articles
Bing Scholar
Similar articles in Bing Scholar
[Wang, Jingxian]'s Articles
[Song, Guoqiang]'s Articles
[Li, Aimin]'s Articles
Terms of Use
No data!
Social Bookmark/Share
File name: Combined chemical and toxicological long-term monitoring for AhR agonists with SPMD-based virtual organisms in drinking water Danjiangkou Reservoir, China.pdf
Format: Adobe PDF
This file does not support browsing at this time
All comments (0)
No comment.
 

Items in the repository are protected by copyright, with all rights reserved, unless otherwise indicated.