中国科学院水生生物研究所机构知识库
Advanced  
IHB OpenIR  > 鱼类生物学及渔业生物技术研究中心  > 期刊论文
题名: Endocrinology: Advances through omics and related technologies
作者: Garcia-Reyero, Natalia1; Tingaud-Sequeira, Angele2; Cao, Mengxi3, 4; Zhu, Zuoyan3; Perkins, Edward J.5; Hu, Wei3
关键词: Omics ; Reproduction ; Transgenic organisms ; Integrative systems biology
刊名: GENERAL AND COMPARATIVE ENDOCRINOLOGY
发表日期: 2014-07-01
DOI: 10.1016/j.ygcen.2014.03.042
卷: 203, 期:-, 页:262-273
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology ; Life Sciences & Biomedicine
类目[WOS]: Endocrinology & Metabolism
研究领域[WOS]: Endocrinology & Metabolism
英文摘要: The rapid development of new omics technologies to measure changes at genetic, transcriptomic, proteomic, and metabolomics levels together with the evolution of methods to analyze and integrate the data at a systems level are revolutionizing the study of biological processes. Here we discuss how new approaches using omics technologies have expanded our knowledge especially in nontraditional models. Our increasing knowledge of these interactions and evolutionary pathway conservation facilitates the use of nontraditional species, both invertebrate and vertebrate, as new model species for biological and endocrinology research. The increasing availability of technology to create organisms overexpressing key genes in endocrine function allows manipulation of complex regulatory networks such as growth hormone (GH) in transgenic fish where disregulation of GH production to produce larger fish has also permitted exploration of the role that GH plays in testis development, suggesting that it does so through interactions with insulin-like growth factors. The availability of omics tools to monitor changes at nearly any level in any organism, manipulate gene expression and behavior, and integrate data across biological levels, provides novel opportunities to explore endocrine function across many species and understand the complex roles that key genes play in different aspects of the endocrine function. (C) 2014 Elsevier Inc. All rights reserved.
关键词[WOS]: ZEBRAFISH DANIO-RERIO ; SALMON ONCORHYNCHUS-KISUTCH ; MINNOWS PIMEPHALES-PROMELAS ; GROWTH-HORMONE SYNTHESIS ; PITUITARY-GONADAL AXIS ; GENE-EXPRESSION ; DAPHNIA-MAGNA ; MESSENGER-RNA ; SYSTEMS BIOLOGY ; RAINBOW-TROUT
语种: 英语
WOS记录号: WOS:000341073300029
ISSN号: 0016-6480
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.ihb.ac.cn/handle/342005/20350
Appears in Collections:鱼类生物学及渔业生物技术研究中心_期刊论文

Files in This Item: Download All
File Name/ File Size Content Type Version Access License
Endocrinology_ Advances through omics and related technologies.pdf(1278KB)----开放获取View Download

作者单位: 1.Mississippi State Univ, Inst Genom Biocomp & Biotechnol, Starkville, MS 39759 USA
2.Univ Bordeaux, Lab MRMG, F-33405 Talence, France
3.Chinese Acad Sci, Inst Hydrobiol, State Key Lab Freshwater Ecol & Biotechnol, Wuhan 430072, Peoples R China
4.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
5.US Army Engineer Res & Dev Ctr, Vicksburg, MS 39180 USA
Service
Recommend this item
Sava as my favorate item
Show this item's statistics
Export Endnote File
Google Scholar
Similar articles in Google Scholar
[Garcia-Reyero, Natalia]'s Articles
[Tingaud-Sequeira, Angele]'s Articles
[Cao, Mengxi]'s Articles
CSDL cross search
Similar articles in CSDL Cross Search
[Garcia-Reyero, Natalia]‘s Articles
[Tingaud-Sequeira, Angele]‘s Articles
[Cao, Mengxi]‘s Articles
Related Copyright Policies
Null
Social Bookmarking
Add to CiteULike Add to Connotea Add to Del.icio.us Add to Digg Add to Reddit
文件名: Endocrinology_ Advances through omics and related technologies.pdf
格式: Adobe PDF
此文件暂不支持浏览
所有评论 (0)
暂无评论
 
评注功能仅针对注册用户开放,请您登录
您对该条目有什么异议,请填写以下表单,管理员会尽快联系您。
内 容:
Email:  *
单位:
验证码:   刷新
您在IR的使用过程中有什么好的想法或者建议可以反馈给我们。
标 题:
 *
内 容:
Email:  *
验证码:   刷新

Items in IR are protected by copyright, with all rights reserved, unless otherwise indicated.

 

 

Valid XHTML 1.0!
Copyright © 2007-2016  中国科学院水生生物研究所 - Feedback
Powered by CSpace