IHB OpenIR  > 鱼类生物学及渔业生物技术研究中心  > 期刊论文
The efficacy of four common anthelmintic drugs and traditional Chinese medicinal plant extracts to control Dactylogyrus vastator (Monogenea)
Zhang, Xiao P.1,2; Li, Wen X.1; Ai, Tao S.3; Zou, Hong1; Wu, Shan G.1; Wang, Gui T.1,2; Wang, GT (reprint author), Chinese Acad Sci, Inst Hydrobiol, Wuhan 430072, Hubei Province, Peoples R China.
2014-01-15
Source PublicationAQUACULTURE
ISSN0044-8486
Volume420Pages:302-307
AbstractDisease caused by Dactylogyrus vastator has resulted in considerable economic damage in aquaculture. To control this parasite effectively, the anthelmintic properties of several extracts obtained from Euphorbia fischeriana and four common anthelmintic drugs (trichlorfon, praziquantel, 40% phoxim and mebendazole) against adults and eggs of D. vastator were assessed in vitro and in vivo. Trichlorfon (0.5, 1 and 1.5 mg/L), praziquantel (10 and 20 mg/L), 40% phoxim (0.1, 0.2 and 0.4 mg/L), mebendazole (0.02 and 0.04 mg/L) and the ethyl acetate extract of E. fischeriana (10 and 20 mg/L) were effective to kill the parasites in vitro, while the other extracts (petroleum ether, n-butanol and distilled water) of E. fischeriana had no significant effects. Praziquantel effectively killed adults with the efficacy of 80.3% at 20 mg/L and inhibited egg hatching, while trichlorfon and the ethyl acetate extract of E. fischeriana effectively eliminated adult parasites with the efficacy of 87.3% and 80.1% at 2.5 mg/L and 14 mg/L, but had no effect on egg viability. 40% phoxim was highly effective in suppressing egg hatching, but mebendazole was not significantly effective on either adults or eggs. Overall, this study found that 40% phoxim and praziquantel could prevent horizontal infection via eggs in aquaculture facilities and that trichlorfon, praziquantel and the ethyl acetate extract of E. fischeriana could be effective against adult parasites. However, the effective dose of the ethyl acetate extract of E. fischeriana was very close to the toxic dose, a factor that likely limits its practical application in aquaculture. (C) 2013 The Authors. Published by Elsevier B.V. All rights reserved.; Disease caused by Dactylogyrus vastator has resulted in considerable economic damage in aquaculture. To control this parasite effectively, the anthelmintic properties of several extracts obtained from Euphorbia fischeriana and four common anthelmintic drugs (trichlorfon, praziquantel, 40% phoxim and mebendazole) against adults and eggs of D. vastator were assessed in vitro and in vivo. Trichlorfon (0.5, 1 and 1.5 mg/L), praziquantel (10 and 20 mg/L), 40% phoxim (0.1, 0.2 and 0.4 mg/L), mebendazole (0.02 and 0.04 mg/L) and the ethyl acetate extract of E. fischeriana (10 and 20 mg/L) were effective to kill the parasites in vitro, while the other extracts (petroleum ether, n-butanol and distilled water) of E. fischeriana had no significant effects. Praziquantel effectively killed adults with the efficacy of 80.3% at 20 mg/L and inhibited egg hatching, while trichlorfon and the ethyl acetate extract of E. fischeriana effectively eliminated adult parasites with the efficacy of 87.3% and 80.1% at 2.5 mg/L and 14 mg/L, but had no effect on egg viability. 40% phoxim was highly effective in suppressing egg hatching, but mebendazole was not significantly effective on either adults or eggs. Overall, this study found that 40% phoxim and praziquantel could prevent horizontal infection via eggs in aquaculture facilities and that trichlorfon, praziquantel and the ethyl acetate extract of E. fischeriana could be effective against adult parasites. However, the effective dose of the ethyl acetate extract of E. fischeriana was very close to the toxic dose, a factor that likely limits its practical application in aquaculture. (C) 2013 The Authors. Published by Elsevier B.V. All rights reserved.
SubtypeArticle
KeywordMonogenea Dactylogyrus Vastator Parasite Control Anthelmintic Efficacy Euphorbia Fischeriana Aquaculture Disease
Department[Zhang, Xiao P. ; Li, Wen X. ; Zou, Hong ; Wu, Shan G. ; Wang, Gui T.] Chinese Acad Sci, Inst Hydrobiol, Wuhan 430072, Hubei Province, Peoples R China ; [Zhang, Xiao P. ; Wang, Gui T.] Univ Chinese Acad Sci, Beijing 100049, Peoples R China ; [Ai, Tao S.] Wuhan Chopper Fishery Biotech Co Ltd, Wuhan 430207, Peoples R China
DOI10.1016/j.aquaculture.2013.09.022
WOS HeadingsScience & Technology ; Life Sciences & Biomedicine
Funding OrganizationNational Natural Science Foundation of China [31272695]; Earmarked Fund for China Agriculture Research System [CARS-46-08] ; National Natural Science Foundation of China [31272695]; Earmarked Fund for China Agriculture Research System [CARS-46-08] ; National Natural Science Foundation of China [31272695]; Earmarked Fund for China Agriculture Research System [CARS-46-08] ; National Natural Science Foundation of China [31272695]; Earmarked Fund for China Agriculture Research System [CARS-46-08]
Indexed BySCI
Language英语
WOS Research AreaFisheries ; Marine & Freshwater Biology
WOS SubjectFisheries ; Marine & Freshwater Biology
WOS IDWOS:000329071300043
WOS KeywordPSEUDODACTYLOGYRUS INFECTIONS ; EUPHORBIA-FISCHERIANA ; PRAZIQUANTEL ; MEBENDAZOLE ; GILLS ; FORMALIN ; EGGS ; EEL ; DITERPENOIDS ; TRICHLORFON
Funding OrganizationNational Natural Science Foundation of China [31272695]; Earmarked Fund for China Agriculture Research System [CARS-46-08] ; National Natural Science Foundation of China [31272695]; Earmarked Fund for China Agriculture Research System [CARS-46-08] ; National Natural Science Foundation of China [31272695]; Earmarked Fund for China Agriculture Research System [CARS-46-08] ; National Natural Science Foundation of China [31272695]; Earmarked Fund for China Agriculture Research System [CARS-46-08]
Citation statistics
Cited Times:16[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.ihb.ac.cn/handle/342005/20053
Collection鱼类生物学及渔业生物技术研究中心_期刊论文
Corresponding AuthorWang, GT (reprint author), Chinese Acad Sci, Inst Hydrobiol, Wuhan 430072, Hubei Province, Peoples R China.
Affiliation1.Chinese Acad Sci, Inst Hydrobiol, Wuhan 430072, Hubei Province, Peoples R China
2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
3.Wuhan Chopper Fishery Biotech Co Ltd, Wuhan 430207, Peoples R China
Recommended Citation
GB/T 7714
Zhang, Xiao P.,Li, Wen X.,Ai, Tao S.,et al. The efficacy of four common anthelmintic drugs and traditional Chinese medicinal plant extracts to control Dactylogyrus vastator (Monogenea)[J]. AQUACULTURE,2014,420:302-307.
APA Zhang, Xiao P..,Li, Wen X..,Ai, Tao S..,Zou, Hong.,Wu, Shan G..,...&Wang, GT .(2014).The efficacy of four common anthelmintic drugs and traditional Chinese medicinal plant extracts to control Dactylogyrus vastator (Monogenea).AQUACULTURE,420,302-307.
MLA Zhang, Xiao P.,et al."The efficacy of four common anthelmintic drugs and traditional Chinese medicinal plant extracts to control Dactylogyrus vastator (Monogenea)".AQUACULTURE 420(2014):302-307.
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