| Identification and expression profiles of prdm1 in medaka Oryzias latipes | |
| Zhao, Haobin1,2; Zhang, Xiaosha1; Cheng, Nana1; Duan, Jundan1; Wang, Jialin1; Nagahama, Yoshitaka2,3; Zhong, Xueping1; Zhou, Qingchun1; Wang, Yaping4; Zhao, HB (reprint author), Cent China Normal Univ, Coll Life Sci, Hubei Key Lab Genet Regulat & Integrat Biol, Wuhan 430079, Peoples R China. | |
| 2014-02-01 | |
| Source Publication | MOLECULAR BIOLOGY REPORTS
 |
| ISSN | 0301-4851 |
| Volume | 41Issue:2Pages:617-626 |
| Abstract | Mouse Prdm1, also known as Blimp1, plays important roles in maturation and survival of lymphoid cells, as well as in organogenesis of muscle, limb, sensor organs and primordial germ cells. The homologues of mouse prdm1 have been identified in a diverse of animals including zebrafish and fugu. Here, we report the identification and expression profiles of two homologues of prdm1, namely prdm1a and prdm1b in medaka, Oryzias latipes. The transcripts of prdm1a and prdm1b were detectable in all the tissues including immune organs such as gill, spleen, kidney, liver and intestine that we have checked on. The transcripts of prdm1a could be detected in the embryonic shield at mid-gastrula stage and later in the somite, eye, otic vesicle, branchial arches, fin, intestine and cloaca during embryogenesis using in situ hybridization. Moreover, the expression of prdm1a in the liver of both medaka and zebrafish could be up-regulated by the immune stimuli including lipopolysaccharide, polyI:C and the grass carp reovirus, similarly to the up-regulation of IL1B. These results indicate that Prdm1a may play important roles in embryogenesis and also in immune response in fish.; Mouse Prdm1, also known as Blimp1, plays important roles in maturation and survival of lymphoid cells, as well as in organogenesis of muscle, limb, sensor organs and primordial germ cells. The homologues of mouse prdm1 have been identified in a diverse of animals including zebrafish and fugu. Here, we report the identification and expression profiles of two homologues of prdm1, namely prdm1a and prdm1b in medaka, Oryzias latipes. The transcripts of prdm1a and prdm1b were detectable in all the tissues including immune organs such as gill, spleen, kidney, liver and intestine that we have checked on. The transcripts of prdm1a could be detected in the embryonic shield at mid-gastrula stage and later in the somite, eye, otic vesicle, branchial arches, fin, intestine and cloaca during embryogenesis using in situ hybridization. Moreover, the expression of prdm1a in the liver of both medaka and zebrafish could be up-regulated by the immune stimuli including lipopolysaccharide, polyI:C and the grass carp reovirus, similarly to the up-regulation of IL1B. These results indicate that Prdm1a may play important roles in embryogenesis and also in immune response in fish. |
| Subtype | Article |
| Keyword | Medaka Zebrafish Prdm1a Prdm1b Embryogenesis Gene Expression Immune Response |
| Department | [Zhao, Haobin ; Zhang, Xiaosha ; Cheng, Nana ; Duan, Jundan ; Wang, Jialin ; Zhong, Xueping ; Zhou, Qingchun] Cent China Normal Univ, Coll Life Sci, Hubei Key Lab Genet Regulat & Integrat Biol, Wuhan 430079, Peoples R China ; [Zhao, Haobin ; Nagahama, Yoshitaka] Japan Soc Promot Sci, Tokyo 1028471, Japan ; [Nagahama, Yoshitaka] Ehime Univ, Inst Collaborat Relat, Matsuyama, Ehime 7908577, Japan ; [Wang, Yaping] Chinese Acad Sci, Inst Hydrobiol, State Key Lab Fresh Water Ecol & Biotechnol, Wuhan 430074, Peoples R China |
| DOI | 10.1007/s11033-013-2899-2 |
| WOS Headings | Science & Technology ; Life Sciences & Biomedicine |
| Funding Organization | National Natural Science Foundation of China [31272645, 30972254, 31071997]; Japan Society for the Promotion of Science ; National Natural Science Foundation of China [31272645, 30972254, 31071997]; Japan Society for the Promotion of Science ; National Natural Science Foundation of China [31272645, 30972254, 31071997]; Japan Society for the Promotion of Science ; National Natural Science Foundation of China [31272645, 30972254, 31071997]; Japan Society for the Promotion of Science |
| Indexed By | SCI |
| Language | 英语 |
| WOS Research Area | Biochemistry & Molecular Biology |
| WOS Subject | Biochemistry & Molecular Biology |
| WOS ID | WOS:000330860900006 |
| WOS Keyword | INDUCED MATURATION PROTEIN-1 ; TRANSCRIPTIONAL REPRESSOR BLIMP1/PRDM1 ; SECRETING PLASMA-CELLS ; TUMOR-SUPPRESSOR GENE ; PRIMORDIAL GERM-CELLS ; B-CELL ; BLIMP-1 EXPRESSION ; NEURAL CREST ; DIFFERENTIATION ; LYMPHOCYTES |
| Funding Organization | National Natural Science Foundation of China [31272645, 30972254, 31071997]; Japan Society for the Promotion of Science ; National Natural Science Foundation of China [31272645, 30972254, 31071997]; Japan Society for the Promotion of Science ; National Natural Science Foundation of China [31272645, 30972254, 31071997]; Japan Society for the Promotion of Science ; National Natural Science Foundation of China [31272645, 30972254, 31071997]; Japan Society for the Promotion of Science |
| Citation statistics | |
| Document Type | 期刊论文 |
| Identifier | http://ir.ihb.ac.cn/handle/342005/20051 |
| Collection | 鱼类生物学及渔业生物技术研究中心_期刊论文 |
| Corresponding Author | Zhao, HB (reprint author), Cent China Normal Univ, Coll Life Sci, Hubei Key Lab Genet Regulat & Integrat Biol, Wuhan 430079, Peoples R China. |
| Affiliation | 1.Cent China Normal Univ, Coll Life Sci, Hubei Key Lab Genet Regulat & Integrat Biol, Wuhan 430079, Peoples R China 2.Japan Soc Promot Sci, Tokyo 1028471, Japan 3.Ehime Univ, Inst Collaborat Relat, Matsuyama, Ehime 7908577, Japan 4.Chinese Acad Sci, Inst Hydrobiol, State Key Lab Fresh Water Ecol & Biotechnol, Wuhan 430074, Peoples R China |
| Recommended Citation GB/T 7714 | Zhao, Haobin,Zhang, Xiaosha,Cheng, Nana,et al. Identification and expression profiles of prdm1 in medaka Oryzias latipes[J]. MOLECULAR BIOLOGY REPORTS,2014,41(2):617-626. |
| APA | Zhao, Haobin.,Zhang, Xiaosha.,Cheng, Nana.,Duan, Jundan.,Wang, Jialin.,...&Zhao, HB .(2014).Identification and expression profiles of prdm1 in medaka Oryzias latipes.MOLECULAR BIOLOGY REPORTS,41(2),617-626. |
| MLA | Zhao, Haobin,et al."Identification and expression profiles of prdm1 in medaka Oryzias latipes".MOLECULAR BIOLOGY REPORTS 41.2(2014):617-626. |
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