IHB OpenIR  > 鱼类生物学及渔业生物技术研究中心  > 期刊论文
Identification and expression profiles of prdm1 in medaka Oryzias latipes
Zhao, Haobin1,2; Zhang, Xiaosha1; Cheng, Nana1; Duan, Jundan1; Wang, Jialin1; Nagahama, Yoshitaka2,3; Zhong, Xueping1; Zhou, Qingchun1; Wang, Yaping4; Zhao, HB (reprint author), Cent China Normal Univ, Coll Life Sci, Hubei Key Lab Genet Regulat & Integrat Biol, Wuhan 430079, Peoples R China.
2014-02-01
Source PublicationMOLECULAR BIOLOGY REPORTS
ISSN0301-4851
Volume41Issue:2Pages:617-626
AbstractMouse Prdm1, also known as Blimp1, plays important roles in maturation and survival of lymphoid cells, as well as in organogenesis of muscle, limb, sensor organs and primordial germ cells. The homologues of mouse prdm1 have been identified in a diverse of animals including zebrafish and fugu. Here, we report the identification and expression profiles of two homologues of prdm1, namely prdm1a and prdm1b in medaka, Oryzias latipes. The transcripts of prdm1a and prdm1b were detectable in all the tissues including immune organs such as gill, spleen, kidney, liver and intestine that we have checked on. The transcripts of prdm1a could be detected in the embryonic shield at mid-gastrula stage and later in the somite, eye, otic vesicle, branchial arches, fin, intestine and cloaca during embryogenesis using in situ hybridization. Moreover, the expression of prdm1a in the liver of both medaka and zebrafish could be up-regulated by the immune stimuli including lipopolysaccharide, polyI:C and the grass carp reovirus, similarly to the up-regulation of IL1B. These results indicate that Prdm1a may play important roles in embryogenesis and also in immune response in fish.; Mouse Prdm1, also known as Blimp1, plays important roles in maturation and survival of lymphoid cells, as well as in organogenesis of muscle, limb, sensor organs and primordial germ cells. The homologues of mouse prdm1 have been identified in a diverse of animals including zebrafish and fugu. Here, we report the identification and expression profiles of two homologues of prdm1, namely prdm1a and prdm1b in medaka, Oryzias latipes. The transcripts of prdm1a and prdm1b were detectable in all the tissues including immune organs such as gill, spleen, kidney, liver and intestine that we have checked on. The transcripts of prdm1a could be detected in the embryonic shield at mid-gastrula stage and later in the somite, eye, otic vesicle, branchial arches, fin, intestine and cloaca during embryogenesis using in situ hybridization. Moreover, the expression of prdm1a in the liver of both medaka and zebrafish could be up-regulated by the immune stimuli including lipopolysaccharide, polyI:C and the grass carp reovirus, similarly to the up-regulation of IL1B. These results indicate that Prdm1a may play important roles in embryogenesis and also in immune response in fish.
SubtypeArticle
KeywordMedaka Zebrafish Prdm1a Prdm1b Embryogenesis Gene Expression Immune Response
Department[Zhao, Haobin ; Zhang, Xiaosha ; Cheng, Nana ; Duan, Jundan ; Wang, Jialin ; Zhong, Xueping ; Zhou, Qingchun] Cent China Normal Univ, Coll Life Sci, Hubei Key Lab Genet Regulat & Integrat Biol, Wuhan 430079, Peoples R China ; [Zhao, Haobin ; Nagahama, Yoshitaka] Japan Soc Promot Sci, Tokyo 1028471, Japan ; [Nagahama, Yoshitaka] Ehime Univ, Inst Collaborat Relat, Matsuyama, Ehime 7908577, Japan ; [Wang, Yaping] Chinese Acad Sci, Inst Hydrobiol, State Key Lab Fresh Water Ecol & Biotechnol, Wuhan 430074, Peoples R China
DOI10.1007/s11033-013-2899-2
WOS HeadingsScience & Technology ; Life Sciences & Biomedicine
Funding OrganizationNational Natural Science Foundation of China [31272645, 30972254, 31071997]; Japan Society for the Promotion of Science ; National Natural Science Foundation of China [31272645, 30972254, 31071997]; Japan Society for the Promotion of Science ; National Natural Science Foundation of China [31272645, 30972254, 31071997]; Japan Society for the Promotion of Science ; National Natural Science Foundation of China [31272645, 30972254, 31071997]; Japan Society for the Promotion of Science
Indexed BySCI
Language英语
WOS Research AreaBiochemistry & Molecular Biology
WOS SubjectBiochemistry & Molecular Biology
WOS IDWOS:000330860900006
WOS KeywordINDUCED MATURATION PROTEIN-1 ; TRANSCRIPTIONAL REPRESSOR BLIMP1/PRDM1 ; SECRETING PLASMA-CELLS ; TUMOR-SUPPRESSOR GENE ; PRIMORDIAL GERM-CELLS ; B-CELL ; BLIMP-1 EXPRESSION ; NEURAL CREST ; DIFFERENTIATION ; LYMPHOCYTES
Funding OrganizationNational Natural Science Foundation of China [31272645, 30972254, 31071997]; Japan Society for the Promotion of Science ; National Natural Science Foundation of China [31272645, 30972254, 31071997]; Japan Society for the Promotion of Science ; National Natural Science Foundation of China [31272645, 30972254, 31071997]; Japan Society for the Promotion of Science ; National Natural Science Foundation of China [31272645, 30972254, 31071997]; Japan Society for the Promotion of Science
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Cited Times:5[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.ihb.ac.cn/handle/342005/20051
Collection鱼类生物学及渔业生物技术研究中心_期刊论文
Corresponding AuthorZhao, HB (reprint author), Cent China Normal Univ, Coll Life Sci, Hubei Key Lab Genet Regulat & Integrat Biol, Wuhan 430079, Peoples R China.
Affiliation1.Cent China Normal Univ, Coll Life Sci, Hubei Key Lab Genet Regulat & Integrat Biol, Wuhan 430079, Peoples R China
2.Japan Soc Promot Sci, Tokyo 1028471, Japan
3.Ehime Univ, Inst Collaborat Relat, Matsuyama, Ehime 7908577, Japan
4.Chinese Acad Sci, Inst Hydrobiol, State Key Lab Fresh Water Ecol & Biotechnol, Wuhan 430074, Peoples R China
Recommended Citation
GB/T 7714
Zhao, Haobin,Zhang, Xiaosha,Cheng, Nana,et al. Identification and expression profiles of prdm1 in medaka Oryzias latipes[J]. MOLECULAR BIOLOGY REPORTS,2014,41(2):617-626.
APA Zhao, Haobin.,Zhang, Xiaosha.,Cheng, Nana.,Duan, Jundan.,Wang, Jialin.,...&Zhao, HB .(2014).Identification and expression profiles of prdm1 in medaka Oryzias latipes.MOLECULAR BIOLOGY REPORTS,41(2),617-626.
MLA Zhao, Haobin,et al."Identification and expression profiles of prdm1 in medaka Oryzias latipes".MOLECULAR BIOLOGY REPORTS 41.2(2014):617-626.
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