IHB OpenIR  > 水生生物多样性与资源保护研究中心  > 期刊论文
The identification of apolipoprotein C-I in rare minnow (Gobiocypris rarus) and its expression following cadmium exposure
Wang, Chunling1,2,3; Zhang, Futie1,2; Cao, Wenxuan1,2; Wang, Jianwei1,2; Zhang, FT (reprint author), Chinese Acad Sci, Inst Hydrobiol, Wuhan 430072, Hubei Province, Peoples R China.
2013-05-01
Source PublicationENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY
ISSN1382-6689
Volume35Issue:3Pages:419-426
AbstractCadmium (Cd) is a ubiquitous environment contaminant that has been detected in a variety of terrestrial and aquatic organisms. In our study, rare minnow were exposed to 0.4 mg/L Cd2+ solution, fish tissues including gill, intestine, kidney, liver, muscle, and spleen were collected at 1, 6, 12,24 and 48 h after exposure. Differential expression sequence tags (ESTs) were screened and an EST similar to Hemibarbus mylodon apolipoprotein C-I (ApoC-I) was identified. The ApoC-I cDNA had been obtained with the sequence of 583 bp, which can code 84 amino acids. The transcription expression patterns of ApoC-I were compared after Cd exposure with the real-time PCR in the above tissues. ApoC-I regulation was prominent in spleen, muscle, gill and liver and moderate in kidney and intestine. This suggests a complex transcriptional regulation of ApoC-I expression following Cd exposure. (c) 2013 Elsevier B.V. All rights reserved.; Cadmium (Cd) is a ubiquitous environment contaminant that has been detected in a variety of terrestrial and aquatic organisms. In our study, rare minnow were exposed to 0.4 mg/L Cd2+ solution, fish tissues including gill, intestine, kidney, liver, muscle, and spleen were collected at 1, 6, 12,24 and 48 h after exposure. Differential expression sequence tags (ESTs) were screened and an EST similar to Hemibarbus mylodon apolipoprotein C-I (ApoC-I) was identified. The ApoC-I cDNA had been obtained with the sequence of 583 bp, which can code 84 amino acids. The transcription expression patterns of ApoC-I were compared after Cd exposure with the real-time PCR in the above tissues. ApoC-I regulation was prominent in spleen, muscle, gill and liver and moderate in kidney and intestine. This suggests a complex transcriptional regulation of ApoC-I expression following Cd exposure. (c) 2013 Elsevier B.V. All rights reserved.
SubtypeArticle
KeywordApolipoprotein C-i Cadmium Gene Expression Rare Minnow
Department[Wang, Chunling ; Zhang, Futie ; Cao, Wenxuan ; Wang, Jianwei] Chinese Acad Sci, Inst Hydrobiol, Wuhan 430072, Hubei Province, Peoples R China ; [Wang, Chunling ; Zhang, Futie ; Cao, Wenxuan ; Wang, Jianwei] Chinese Acad Sci, Key Lab Aquat Biodivers & Conservat, Wuhan 430072, Hubei Province, Peoples R China ; [Wang, Chunling] Univ Chinese Acad Sci, Beijing 100039, Peoples R China
DOI10.1016/j.etap.2013.02.004
WOS HeadingsScience & Technology ; Life Sciences & Biomedicine
Funding OrganizationNational Natural Science Foundation of China [30900154]; Knowledge Innovation Program of the Chinese Academy of Sciences [Y15E011101]; National 863 High Technology Research Program of China [2012AA06A302-4] ; National Natural Science Foundation of China [30900154]; Knowledge Innovation Program of the Chinese Academy of Sciences [Y15E011101]; National 863 High Technology Research Program of China [2012AA06A302-4] ; National Natural Science Foundation of China [30900154]; Knowledge Innovation Program of the Chinese Academy of Sciences [Y15E011101]; National 863 High Technology Research Program of China [2012AA06A302-4] ; National Natural Science Foundation of China [30900154]; Knowledge Innovation Program of the Chinese Academy of Sciences [Y15E011101]; National 863 High Technology Research Program of China [2012AA06A302-4]
Indexed BySCI
Language英语
WOS Research AreaEnvironmental Sciences & Ecology ; Pharmacology & Pharmacy ; Toxicology
WOS SubjectEnvironmental Sciences ; Pharmacology & Pharmacy ; Toxicology
WOS IDWOS:000317943500008
WOS KeywordPERFLUOROOCTANOIC ACID ; SYNECHOGOBIUS-HASTA ; MOLECULAR-CLONING ; MULTIGENE FAMILY ; OXIDATIVE STRESS ; FISH ; RESPONSES ; GENE ; ACCUMULATION ; VITELLOGENIN
Funding OrganizationNational Natural Science Foundation of China [30900154]; Knowledge Innovation Program of the Chinese Academy of Sciences [Y15E011101]; National 863 High Technology Research Program of China [2012AA06A302-4] ; National Natural Science Foundation of China [30900154]; Knowledge Innovation Program of the Chinese Academy of Sciences [Y15E011101]; National 863 High Technology Research Program of China [2012AA06A302-4] ; National Natural Science Foundation of China [30900154]; Knowledge Innovation Program of the Chinese Academy of Sciences [Y15E011101]; National 863 High Technology Research Program of China [2012AA06A302-4] ; National Natural Science Foundation of China [30900154]; Knowledge Innovation Program of the Chinese Academy of Sciences [Y15E011101]; National 863 High Technology Research Program of China [2012AA06A302-4]
Citation statistics
Document Type期刊论文
Identifierhttp://ir.ihb.ac.cn/handle/342005/19258
Collection水生生物多样性与资源保护研究中心_期刊论文
Corresponding AuthorZhang, FT (reprint author), Chinese Acad Sci, Inst Hydrobiol, Wuhan 430072, Hubei Province, Peoples R China.
Affiliation1.Chinese Acad Sci, Inst Hydrobiol, Wuhan 430072, Hubei Province, Peoples R China
2.Chinese Acad Sci, Key Lab Aquat Biodivers & Conservat, Wuhan 430072, Hubei Province, Peoples R China
3.Univ Chinese Acad Sci, Beijing 100039, Peoples R China
Recommended Citation
GB/T 7714
Wang, Chunling,Zhang, Futie,Cao, Wenxuan,et al. The identification of apolipoprotein C-I in rare minnow (Gobiocypris rarus) and its expression following cadmium exposure[J]. ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY,2013,35(3):419-426.
APA Wang, Chunling,Zhang, Futie,Cao, Wenxuan,Wang, Jianwei,&Zhang, FT .(2013).The identification of apolipoprotein C-I in rare minnow (Gobiocypris rarus) and its expression following cadmium exposure.ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY,35(3),419-426.
MLA Wang, Chunling,et al."The identification of apolipoprotein C-I in rare minnow (Gobiocypris rarus) and its expression following cadmium exposure".ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY 35.3(2013):419-426.
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