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题名: Histone variants and histone exchange
作者: Wu Nan (wunan@ihb.ac.cn) ; Gui Jian-Fang (jfgui@ihb.ac.cn)
通讯作者: Wu Nan ; Chinese Acad Sci, Inst Hydrobiol, State Key Lab Freshwater Ecol and Biotechnol, Wuhan 430072, Peoples R China
刊名: Yichuan
发表日期: 2006
卷: 28, 期:4, 页:493-500
收录类别: 其他
英文摘要: Histories, as basic components of nucleosome. are essential to chromatin structure and function. To adapt to various states of chromatin, corresponding histone variants are incorporated in nucleosome, and certain modifications also occur on the variants tails. These variants change the conformation and stability of nucleosome to facilitate transcriptional activation or deactivation, DNA repairing, heterochromatin formation. and others. During histone exchange, chromatin remodeling complex facilitates histone variant deposition into nucleosome, and different variants have diverse deposition pathways. Recently, research on histone variants is not only a new hotspot in epigenetics, but also a new annotation of "histone code". In addition, histone exchange reveals new changing mechanism of DNA-histone interaction.
ISSN号: 0253-9772
内容类型: 期刊论文
URI标识: http://ir.ihb.ac.cn/handle/342005/18369
Appears in Collections:中科院水生所知识产出(2009年前)_期刊论文

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Wu Nan (wunan@ihb.ac.cn) ; Gui Jian-Fang (jfgui@ihb.ac.cn).Histone variants and histone exchange,Yichuan,2006,28(4):493-500
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