This paper describes the histopathological changes in the tissues of rare minnow (Gobiocypris rarus) with hemorrhage caused by artificial infection of hemorrhagic virus of grass carp (GCHV). Extravasation, microthrombi and erythrocyte infiltration in the myofibrer appeared in the muscular system of the diseased fish. In the gill, the hyperplasia and hypertrophy of branchial epithelial cell led to the fusion of the secondary lamellae; the extravasation and rupture of erythrocyte result the formation of thrombi and blood bubble. The intestinal epithelial droped and erythrocyte scattered all over the mucous membrane and intestinal intima. The hepatic cell hypertrophy, hepatic parenchyma bubbling and enlargement among the gap of hepatic cells were found in the liver section of the diseased fish. Yellow-brownish nods increased in the spleen section. The results above indicate that the histopathological change is the result of GCHV infection, and rare minnow is sensitive to GCHV.
Wang Tiehui, Yi Yonglan; Chen Hongxi; Liu Hanqin; Guo Wen.Histopathological observation on hemorrhagic rare minnow (Gobiocypris rarus) infected artificially with hemorrhagic virus of grass carp,Acta Hydrobiologica Sinica,1995,19(4):350-353