| Damage to DNA caused by UV-B radiation in the desert cyanobacterium Scytonema javanicum and the effects of exogenous chemicals on the process | |
| Wang, Gaohong2; Deng, Songqiang1; Li, Cheng1; Liu, Yongding2; Chen, Lanzhou1,2; Hu, Chaozhen1; Chen, LZ (reprint author), Wuhan Univ, Sch Resource & Environm Sci, Hubei Key Lab Biomass Resources Chem & Environm B, Wuhan 430079, Peoples R China. | |
| 2012-07-01 | |
| Source Publication | CHEMOSPHERE
 |
| ISSN | 0045-6535 |
| Volume | 88Issue:4Pages:413-417 |
| Abstract | Radiation with UV-B increased the damage to DNA in Scytonema javanicum, a desert-dwelling soil microorganism, and the level of damage varied with the intensity of UV-B radiation and duration of exposure. Production of reactive oxygen species (ROS) also increased because of the radiation. Different exogenous chemicals (ascorbate acid, ASC; N-acetylcysteine, NAC; glyphosate, GPS; and 2-methyl-4-chlorophenoxy-acetic acid, MCPA-Na) differed in their effect on the extent of DNA damage and ROS production: whereas NAC and ASC protected the DNA from damage and resulted in reduced ROS production, the herbicides (GPS and MCPA-Na) increased the extent of damage, lowered the rate of photosynthesis, and differed in their effect on ROS production. The chemicals probably have different mechanisms to exercise their effects: NAC and ASC probably function as antioxidant agents or as precursors of other antioxidant molecules that protect the DNA and photosynthetic apparatus directly from the ROS produced as a result of UV-B radiation, and GPS and MCPA-Na probably disrupt the normal metabolism in S. javanicum to induce the leaking of ROS into the photosynthetic electron transfer pathway following UV-B radiation, and thereby damage the DNA. Such mechanisms have serious implications for the use of environment-friendly herbicides, which, because they can destroy DNA, may prove harmful to soil microorganisms. (C) 2012 Elsevier Ltd. All rights reserved.; Radiation with UV-B increased the damage to DNA in Scytonema javanicum, a desert-dwelling soil microorganism, and the level of damage varied with the intensity of UV-B radiation and duration of exposure. Production of reactive oxygen species (ROS) also increased because of the radiation. Different exogenous chemicals (ascorbate acid, ASC; N-acetylcysteine, NAC; glyphosate, GPS; and 2-methyl-4-chlorophenoxy-acetic acid, MCPA-Na) differed in their effect on the extent of DNA damage and ROS production: whereas NAC and ASC protected the DNA from damage and resulted in reduced ROS production, the herbicides (GPS and MCPA-Na) increased the extent of damage, lowered the rate of photosynthesis, and differed in their effect on ROS production. The chemicals probably have different mechanisms to exercise their effects: NAC and ASC probably function as antioxidant agents or as precursors of other antioxidant molecules that protect the DNA and photosynthetic apparatus directly from the ROS produced as a result of UV-B radiation, and GPS and MCPA-Na probably disrupt the normal metabolism in S. javanicum to induce the leaking of ROS into the photosynthetic electron transfer pathway following UV-B radiation, and thereby damage the DNA. Such mechanisms have serious implications for the use of environment-friendly herbicides, which, because they can destroy DNA, may prove harmful to soil microorganisms. (C) 2012 Elsevier Ltd. All rights reserved. |
| Subtype | Article |
| Keyword | Desert Soil Cyanobacteria Uv-b Dna Damage Ros Herbicides Exogenous Chemicals |
| Department | [Deng, Songqiang; Li, Cheng; Chen, Lanzhou; Hu, Chaozhen] Wuhan Univ, Sch Resource & Environm Sci, Hubei Key Lab Biomass Resources Chem & Environm B, Wuhan 430079, Peoples R China; [Wang, Gaohong; Liu, Yongding; Chen, Lanzhou] Chinese Acad Sci, State Key Lab Freshwater Ecol & Biotechnol, Inst Hydrobiol, Wuhan 430072, Peoples R China |
| DOI | 10.1016/j.chemosphere.2012.02.056 |
| WOS Headings | Science & Technology ; Life Sciences & Biomedicine |
| Funding Organization | National Major Programs of Water Body Pollution Control and Remediation[2009ZX07104-005-02, 2008ZX07105-005]; Chinese Natural Science Foundation[30970446, 30500068, 30970688]; Chinese Manned Spaceflight Project ; National Major Programs of Water Body Pollution Control and Remediation[2009ZX07104-005-02, 2008ZX07105-005]; Chinese Natural Science Foundation[30970446, 30500068, 30970688]; Chinese Manned Spaceflight Project ; National Major Programs of Water Body Pollution Control and Remediation[2009ZX07104-005-02, 2008ZX07105-005]; Chinese Natural Science Foundation[30970446, 30500068, 30970688]; Chinese Manned Spaceflight Project ; National Major Programs of Water Body Pollution Control and Remediation[2009ZX07104-005-02, 2008ZX07105-005]; Chinese Natural Science Foundation[30970446, 30500068, 30970688]; Chinese Manned Spaceflight Project |
| Indexed By | SCI |
| Language | 英语 |
| WOS Research Area | Environmental Sciences & Ecology |
| WOS Subject | Environmental Sciences |
| WOS ID | WOS:000305266300007 |
| WOS Keyword | ALLEVIATES OXIDATIVE DAMAGE ; ACETYL-L-CYSTEINE ; NITRIC-OXIDE ; ANTIOXIDANT ENZYMES ; GREEN-ALGAE ; NOSTOC SP ; STRESS ; CHLORELLA ; TOXICITY ; SYSTEM |
| Funding Organization | National Major Programs of Water Body Pollution Control and Remediation[2009ZX07104-005-02, 2008ZX07105-005]; Chinese Natural Science Foundation[30970446, 30500068, 30970688]; Chinese Manned Spaceflight Project ; National Major Programs of Water Body Pollution Control and Remediation[2009ZX07104-005-02, 2008ZX07105-005]; Chinese Natural Science Foundation[30970446, 30500068, 30970688]; Chinese Manned Spaceflight Project ; National Major Programs of Water Body Pollution Control and Remediation[2009ZX07104-005-02, 2008ZX07105-005]; Chinese Natural Science Foundation[30970446, 30500068, 30970688]; Chinese Manned Spaceflight Project ; National Major Programs of Water Body Pollution Control and Remediation[2009ZX07104-005-02, 2008ZX07105-005]; Chinese Natural Science Foundation[30970446, 30500068, 30970688]; Chinese Manned Spaceflight Project |
| Citation statistics | |
| Document Type | 期刊论文 |
| Identifier | http://ir.ihb.ac.cn/handle/342005/17007 |
| Collection | 水环境工程研究中心_期刊论文 |
| Corresponding Author | Chen, LZ (reprint author), Wuhan Univ, Sch Resource & Environm Sci, Hubei Key Lab Biomass Resources Chem & Environm B, Wuhan 430079, Peoples R China. |
| Affiliation | 1.Wuhan Univ, Sch Resource & Environm Sci, Hubei Key Lab Biomass Resources Chem & Environm B, Wuhan 430079, Peoples R China 2.Chinese Acad Sci, State Key Lab Freshwater Ecol & Biotechnol, Inst Hydrobiol, Wuhan 430072, Peoples R China |
| Recommended Citation GB/T 7714 | Wang, Gaohong,Deng, Songqiang,Li, Cheng,et al. Damage to DNA caused by UV-B radiation in the desert cyanobacterium Scytonema javanicum and the effects of exogenous chemicals on the process[J]. CHEMOSPHERE,2012,88(4):413-417. |
| APA | Wang, Gaohong.,Deng, Songqiang.,Li, Cheng.,Liu, Yongding.,Chen, Lanzhou.,...&Chen, LZ .(2012).Damage to DNA caused by UV-B radiation in the desert cyanobacterium Scytonema javanicum and the effects of exogenous chemicals on the process.CHEMOSPHERE,88(4),413-417. |
| MLA | Wang, Gaohong,et al."Damage to DNA caused by UV-B radiation in the desert cyanobacterium Scytonema javanicum and the effects of exogenous chemicals on the process".CHEMOSPHERE 88.4(2012):413-417. |
| Files in This Item: | ||||||
| File Name/Size | DocType | Version | Access | License | ||
| Damage to DNA caused（338KB） | 开放获取 | -- | View Application Full Text | |||
Items in the repository are protected by copyright, with all rights reserved, unless otherwise indicated.
Edit Comment