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Damage to DNA caused by UV-B radiation in the desert cyanobacterium Scytonema javanicum and the effects of exogenous chemicals on the process
Wang, Gaohong2; Deng, Songqiang1; Li, Cheng1; Liu, Yongding2; Chen, Lanzhou1,2; Hu, Chaozhen1; Chen, LZ (reprint author), Wuhan Univ, Sch Resource & Environm Sci, Hubei Key Lab Biomass Resources Chem & Environm B, Wuhan 430079, Peoples R China.
2012-07-01
Source PublicationCHEMOSPHERE
ISSN0045-6535
Volume88Issue:4Pages:413-417
AbstractRadiation with UV-B increased the damage to DNA in Scytonema javanicum, a desert-dwelling soil microorganism, and the level of damage varied with the intensity of UV-B radiation and duration of exposure. Production of reactive oxygen species (ROS) also increased because of the radiation. Different exogenous chemicals (ascorbate acid, ASC; N-acetylcysteine, NAC; glyphosate, GPS; and 2-methyl-4-chlorophenoxy-acetic acid, MCPA-Na) differed in their effect on the extent of DNA damage and ROS production: whereas NAC and ASC protected the DNA from damage and resulted in reduced ROS production, the herbicides (GPS and MCPA-Na) increased the extent of damage, lowered the rate of photosynthesis, and differed in their effect on ROS production. The chemicals probably have different mechanisms to exercise their effects: NAC and ASC probably function as antioxidant agents or as precursors of other antioxidant molecules that protect the DNA and photosynthetic apparatus directly from the ROS produced as a result of UV-B radiation, and GPS and MCPA-Na probably disrupt the normal metabolism in S. javanicum to induce the leaking of ROS into the photosynthetic electron transfer pathway following UV-B radiation, and thereby damage the DNA. Such mechanisms have serious implications for the use of environment-friendly herbicides, which, because they can destroy DNA, may prove harmful to soil microorganisms. (C) 2012 Elsevier Ltd. All rights reserved.; Radiation with UV-B increased the damage to DNA in Scytonema javanicum, a desert-dwelling soil microorganism, and the level of damage varied with the intensity of UV-B radiation and duration of exposure. Production of reactive oxygen species (ROS) also increased because of the radiation. Different exogenous chemicals (ascorbate acid, ASC; N-acetylcysteine, NAC; glyphosate, GPS; and 2-methyl-4-chlorophenoxy-acetic acid, MCPA-Na) differed in their effect on the extent of DNA damage and ROS production: whereas NAC and ASC protected the DNA from damage and resulted in reduced ROS production, the herbicides (GPS and MCPA-Na) increased the extent of damage, lowered the rate of photosynthesis, and differed in their effect on ROS production. The chemicals probably have different mechanisms to exercise their effects: NAC and ASC probably function as antioxidant agents or as precursors of other antioxidant molecules that protect the DNA and photosynthetic apparatus directly from the ROS produced as a result of UV-B radiation, and GPS and MCPA-Na probably disrupt the normal metabolism in S. javanicum to induce the leaking of ROS into the photosynthetic electron transfer pathway following UV-B radiation, and thereby damage the DNA. Such mechanisms have serious implications for the use of environment-friendly herbicides, which, because they can destroy DNA, may prove harmful to soil microorganisms. (C) 2012 Elsevier Ltd. All rights reserved.
SubtypeArticle
KeywordDesert Soil Cyanobacteria Uv-b Dna Damage Ros Herbicides Exogenous Chemicals
Department[Deng, Songqiang; Li, Cheng; Chen, Lanzhou; Hu, Chaozhen] Wuhan Univ, Sch Resource & Environm Sci, Hubei Key Lab Biomass Resources Chem & Environm B, Wuhan 430079, Peoples R China; [Wang, Gaohong; Liu, Yongding; Chen, Lanzhou] Chinese Acad Sci, State Key Lab Freshwater Ecol & Biotechnol, Inst Hydrobiol, Wuhan 430072, Peoples R China
DOI10.1016/j.chemosphere.2012.02.056
WOS HeadingsScience & Technology ; Life Sciences & Biomedicine
Funding OrganizationNational Major Programs of Water Body Pollution Control and Remediation[2009ZX07104-005-02, 2008ZX07105-005]; Chinese Natural Science Foundation[30970446, 30500068, 30970688]; Chinese Manned Spaceflight Project ; National Major Programs of Water Body Pollution Control and Remediation[2009ZX07104-005-02, 2008ZX07105-005]; Chinese Natural Science Foundation[30970446, 30500068, 30970688]; Chinese Manned Spaceflight Project ; National Major Programs of Water Body Pollution Control and Remediation[2009ZX07104-005-02, 2008ZX07105-005]; Chinese Natural Science Foundation[30970446, 30500068, 30970688]; Chinese Manned Spaceflight Project ; National Major Programs of Water Body Pollution Control and Remediation[2009ZX07104-005-02, 2008ZX07105-005]; Chinese Natural Science Foundation[30970446, 30500068, 30970688]; Chinese Manned Spaceflight Project
Indexed BySCI
Language英语
WOS Research AreaEnvironmental Sciences & Ecology
WOS SubjectEnvironmental Sciences
WOS IDWOS:000305266300007
WOS KeywordALLEVIATES OXIDATIVE DAMAGE ; ACETYL-L-CYSTEINE ; NITRIC-OXIDE ; ANTIOXIDANT ENZYMES ; GREEN-ALGAE ; NOSTOC SP ; STRESS ; CHLORELLA ; TOXICITY ; SYSTEM
Funding OrganizationNational Major Programs of Water Body Pollution Control and Remediation[2009ZX07104-005-02, 2008ZX07105-005]; Chinese Natural Science Foundation[30970446, 30500068, 30970688]; Chinese Manned Spaceflight Project ; National Major Programs of Water Body Pollution Control and Remediation[2009ZX07104-005-02, 2008ZX07105-005]; Chinese Natural Science Foundation[30970446, 30500068, 30970688]; Chinese Manned Spaceflight Project ; National Major Programs of Water Body Pollution Control and Remediation[2009ZX07104-005-02, 2008ZX07105-005]; Chinese Natural Science Foundation[30970446, 30500068, 30970688]; Chinese Manned Spaceflight Project ; National Major Programs of Water Body Pollution Control and Remediation[2009ZX07104-005-02, 2008ZX07105-005]; Chinese Natural Science Foundation[30970446, 30500068, 30970688]; Chinese Manned Spaceflight Project
Citation statistics
Cited Times:25[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.ihb.ac.cn/handle/342005/17007
Collection水环境工程研究中心_期刊论文
Corresponding AuthorChen, LZ (reprint author), Wuhan Univ, Sch Resource & Environm Sci, Hubei Key Lab Biomass Resources Chem & Environm B, Wuhan 430079, Peoples R China.
Affiliation1.Wuhan Univ, Sch Resource & Environm Sci, Hubei Key Lab Biomass Resources Chem & Environm B, Wuhan 430079, Peoples R China
2.Chinese Acad Sci, State Key Lab Freshwater Ecol & Biotechnol, Inst Hydrobiol, Wuhan 430072, Peoples R China
Recommended Citation
GB/T 7714
Wang, Gaohong,Deng, Songqiang,Li, Cheng,et al. Damage to DNA caused by UV-B radiation in the desert cyanobacterium Scytonema javanicum and the effects of exogenous chemicals on the process[J]. CHEMOSPHERE,2012,88(4):413-417.
APA Wang, Gaohong.,Deng, Songqiang.,Li, Cheng.,Liu, Yongding.,Chen, Lanzhou.,...&Chen, LZ .(2012).Damage to DNA caused by UV-B radiation in the desert cyanobacterium Scytonema javanicum and the effects of exogenous chemicals on the process.CHEMOSPHERE,88(4),413-417.
MLA Wang, Gaohong,et al."Damage to DNA caused by UV-B radiation in the desert cyanobacterium Scytonema javanicum and the effects of exogenous chemicals on the process".CHEMOSPHERE 88.4(2012):413-417.
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