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Bacterial Community Assembly and Turnover within the Intestines of Developing Zebrafish
Yan, Qingyun1; van der Gast, Christopher J.2; Yu, Yuhe1; Yan, QY (reprint author), Chinese Acad Sci, Inst Hydrobiol, Key Lab Biodivers & Conservat Aquat Organisms, Wuhan, Peoples R China.
2012-01-19
Source PublicationPLOS ONE
ISSN1932-6203
Volume7Issue:1Pages:e30603
AbstractBackground: The majority of animal associated microorganisms are present in digestive tract communities. These intestinal communities arise from selective pressures of the gut habitats as well as host's genotype are regarded as an extra 'organ' regulate functions that have not evolved wholly on the host. They are functionally essential in providing nourishment, regulating epithelial development, and influencing immunity in the vertebrate host. As vertebrates are born free of microorganisms, what is poorly understood is how intestinal bacterial communities assemble and develop in conjunction with the development of the host. Methodology/Principal Findings: Set within an ecological framework, we investigated the bacterial community assembly and turnover within the intestinal habitats of developing zebrafish (from larvae to adult animals). Spatial and temporal species-richness relationships and Mantel and partial Mantel tests revealed that turnover was low and that richness and composition was best predicted by time and not intestinal volume (habitat size) or changes in food diet. We also observed that bacterial communities within the zebrafish intestines were deterministically assembled (reflected by the observed low turnover) switching to stochastic assembly in the later stages of zebrafish development. Conclusions/Significance: This study is of importance as it provides a novel insight into how intestinal bacterial communities assemble in tandem with the host's development (from early to adult stages). It is our hope that by studying intestinal microbiota of this vertebrate model with such or some more refined approaches in the future could well provide ecological insights for clinical benefit. In addition, this study also adds to our still fledgling knowledge of how spatial and temporal species-richness relationships are shaped and provides further mounting evidence that bacterial community assembly and dynamics are shaped by both deterministic and stochastic considerations.; Background: The majority of animal associated microorganisms are present in digestive tract communities. These intestinal communities arise from selective pressures of the gut habitats as well as host's genotype are regarded as an extra 'organ' regulate functions that have not evolved wholly on the host. They are functionally essential in providing nourishment, regulating epithelial development, and influencing immunity in the vertebrate host. As vertebrates are born free of microorganisms, what is poorly understood is how intestinal bacterial communities assemble and develop in conjunction with the development of the host.
SubtypeArticle
KeywordGradient Gel-electrophoresis Species-diversity Faunal Similarity Microbial Ecology Genetic-analysis Nature Reserves Gut Microbiota Waste-water In-vivo Taxa
Department[Yan, Qingyun; Yu, Yuhe] Chinese Acad Sci, Inst Hydrobiol, Key Lab Biodivers & Conservat Aquat Organisms, Wuhan, Peoples R China; [van der Gast, Christopher J.] NERC Ctr Ecol & Hydrol, Wallingford, Oxon, England
DOI10.1371/journal.pone.0030603
WOS HeadingsScience & Technology
Funding OrganizationMajor State Basic Research Development Program of China[2009CB118705]; National Natural Science Foundation of China[30970358]; UK Natural Environment Research Council (NERC) ; Major State Basic Research Development Program of China[2009CB118705]; National Natural Science Foundation of China[30970358]; UK Natural Environment Research Council (NERC) ; Major State Basic Research Development Program of China[2009CB118705]; National Natural Science Foundation of China[30970358]; UK Natural Environment Research Council (NERC) ; Major State Basic Research Development Program of China[2009CB118705]; National Natural Science Foundation of China[30970358]; UK Natural Environment Research Council (NERC)
Indexed BySCI
Language英语
WOS Research AreaScience & Technology - Other Topics
WOS SubjectMultidisciplinary Sciences
WOS IDWOS:000301457200069
WOS KeywordGRADIENT GEL-ELECTROPHORESIS ; SPECIES-DIVERSITY ; FAUNAL SIMILARITY ; MICROBIAL ECOLOGY ; GENETIC-ANALYSIS ; NATURE-RESERVES ; GUT MICROBIOTA ; WASTE-WATER ; IN-VIVO ; TAXA
Funding OrganizationMajor State Basic Research Development Program of China[2009CB118705]; National Natural Science Foundation of China[30970358]; UK Natural Environment Research Council (NERC) ; Major State Basic Research Development Program of China[2009CB118705]; National Natural Science Foundation of China[30970358]; UK Natural Environment Research Council (NERC) ; Major State Basic Research Development Program of China[2009CB118705]; National Natural Science Foundation of China[30970358]; UK Natural Environment Research Council (NERC) ; Major State Basic Research Development Program of China[2009CB118705]; National Natural Science Foundation of China[30970358]; UK Natural Environment Research Council (NERC)
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Document Type期刊论文
Identifierhttp://ir.ihb.ac.cn/handle/342005/16887
Collection淡水生态学研究中心_期刊论文
Corresponding AuthorYan, QY (reprint author), Chinese Acad Sci, Inst Hydrobiol, Key Lab Biodivers & Conservat Aquat Organisms, Wuhan, Peoples R China.
Affiliation1.Chinese Acad Sci, Inst Hydrobiol, Key Lab Biodivers & Conservat Aquat Organisms, Wuhan, Peoples R China
2.NERC Ctr Ecol & Hydrol, Wallingford, Oxon, England
Recommended Citation
GB/T 7714
Yan, Qingyun,van der Gast, Christopher J.,Yu, Yuhe,et al. Bacterial Community Assembly and Turnover within the Intestines of Developing Zebrafish[J]. PLOS ONE,2012,7(1):e30603.
APA Yan, Qingyun,van der Gast, Christopher J.,Yu, Yuhe,&Yan, QY .(2012).Bacterial Community Assembly and Turnover within the Intestines of Developing Zebrafish.PLOS ONE,7(1),e30603.
MLA Yan, Qingyun,et al."Bacterial Community Assembly and Turnover within the Intestines of Developing Zebrafish".PLOS ONE 7.1(2012):e30603.
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