中国科学院水生生物研究所机构知识库
Advanced  
IHB OpenIR  > 鱼类生物学及渔业生物技术研究中心  > 会议论文
题名: Developmental expression of steroidogenic factor-1, cyp19a1a and cyp19a1b from common carp (Cyprinus carpio)
作者: Tang, Bin ; Hu, Wei ; Hao, Jun ; Zhu, Zuoyan
会议文集: GENERAL AND COMPARATIVE ENDOCRINOLOGY
会议名称: 2nd International Symposium for Fish Growth and Reporduction
会议日期: JUN 20-21, 2009
出版日期: 2010
会议地点: Hong Kong, PEOPLES R CHINA
关键词: SF-1 ; cyp19a1a ; cyp19a1b ; Developmental expression ; Gonad development
通讯作者: Hu, W, Chinese Acad Sci, Inst Hydrobiol, State Key Lab Freshwater Ecol & Biotechnol, Wuhan 430072, Peoples R China
出版者: ACADEMIC PRESS INC ELSEVIER SCIENCE
出版地: SAN DIEGO
收录类别: SCI
ISSN: 0016-6480
部门归属: [Tang, Bin; Hu, Wei; Zhu, Zuoyan] Chinese Acad Sci, Inst Hydrobiol, State Key Lab Freshwater Ecol & Biotechnol, Wuhan 430072, Peoples R China; [Tang, Bin; Hao, Jun; Zhu, Zuoyan] Wuhan Univ, Coll Life Sci, Wuhan 430072, Peoples R China
摘要: Steroidogenic factor-1 (SF-1), cyp19a1a and cyp19a1b play pivotal roles in vertebrate steroidogenesis and reproduction. In this study, a SF-1 cDNA (EU022463) was cloned from common carp (Cyprinus carpio). The transcript contains a 1509 base pair (bp) open reading frame (ORF) encoding a 503 amino acid sequence. Comparisons of deduced amino acid sequences demonstrated that carp SF-1 is highly homologous with those of other vertebrates. Tissue specific expressions of SF-1, cyp19a1a and cyp19a1b mRNA were analyzed in 10-month-old carp. SF-1 was abundant in the hypothalamus, pituitary, gonad, spleen and liver (females only). Cyp19a1b was preferentially expressed in the brain of both sexes but also was present at much lower levels in testis, ovary and kidney (females only). Although cyp19a1a expression was preferentially expressed in ovaries, it was also present at much lower levels in brain, testis, kidney and spleen (males only). Northern blot analysis revealed that testes and brains of both sexes expressed a transcript of about 2.8 kb in size. The expression pattern of SF-1, cyp19a1a and cyp19a1b in carp gonads suggested their involvement in sexual development. In 3-month-old carp, SF-1 and cyp19a1b were expressed highly in testes but were at much lower levels in ovaries, while the opposite pattern was observed with cyp19a1a expression. In 10-month-old carp, SF-1 expression was much higher in testes than in ovaries, while the opposite pattern was observed with cyp19a1a expression. These developmental expression patterns in carp gonads suggest important roles of SF-1 and cyp19a1b in testis development and of cyp19a1a in ovary development. (C) 2010 Elsevier Inc. All rights reserved.
语种: 英语
Citation statistics:
内容类型: 会议论文
URI标识: http://ir.ihb.ac.cn/handle/342005/13876
Appears in Collections:鱼类生物学及渔业生物技术研究中心_会议论文

Files in This Item: Download All
File Name/ File Size Content Type Version Access License
Developmental expression of steroidogenic factor-1.pdf(1389KB)----开放获取--View Download

Recommended Citation:
Tang, Bin; Hu, Wei; Hao, Jun; Zhu, Zuoyan.Developmental expression of steroidogenic factor-1, cyp19a1a and cyp19a1b from common carp (Cyprinus carpio).见:ACADEMIC PRESS INC ELSEVIER SCIENCE.GENERAL AND COMPARATIVE ENDOCRINOLOGY,SAN DIEGO,2010,408-416
Service
Recommend this item
Sava as my favorate item
Show this item's statistics
Export Endnote File
Google Scholar
Similar articles in Google Scholar
[Tang, Bin]'s Articles
[Hu, Wei]'s Articles
[Hao, Jun]'s Articles
CSDL cross search
Similar articles in CSDL Cross Search
[Tang, Bin]‘s Articles
[Hu, Wei]‘s Articles
[Hao, Jun]‘s Articles
Related Copyright Policies
Null
Social Bookmarking
Add to CiteULike Add to Connotea Add to Del.icio.us Add to Digg Add to Reddit
文件名: Developmental expression of steroidogenic factor-1.pdf
格式: Adobe PDF
所有评论 (0)
暂无评论
 
评注功能仅针对注册用户开放,请您登录
您对该条目有什么异议,请填写以下表单,管理员会尽快联系您。
内 容:
Email:  *
单位:
验证码:   刷新
您在IR的使用过程中有什么好的想法或者建议可以反馈给我们。
标 题:
 *
内 容:
Email:  *
验证码:   刷新

Items in IR are protected by copyright, with all rights reserved, unless otherwise indicated.

 

 

Valid XHTML 1.0!
Copyright © 2007-2016  中国科学院水生生物研究所 - Feedback
Powered by CSpace