IHB OpenIR  > 鱼类生物学及渔业生物技术研究中心  > 期刊论文
Medaka fish stem cells and their applications
Yi MeiSheng; Hong Ni; Li ZhenDong; Yan Yan; Wang DanKe; Zhao HaoBin; Hong YunHan; Hong, YH, Natl Univ Singapore, Dept Biol Sci, 10 Kent Ridge Crescent, Singapore 119260, Singapore
2010
Source PublicationSCIENCE CHINA-LIFE SCIENCES
Volume53Issue:4Pages:426-434
AbstractStem cells are present in developing embryos and adult tissues of multicellular organisms. Owing to their unique features, stem cells provide excellent opportunities for experimental analyses of basic developmental processes such as pluripotency control and cell fate decision and for regenerative medicine by stem cell-based therapy. Stem cell cultures have been best studied in 3 vertebrate organisms. These are the mouse, human and a small laboratory fish called medaka. Specifically, medaka has given rise to the first embryonic stem (ES) cells besides the mouse, the first adult testis-derived male stem cells spermatogonia capable of test-tube sperm production, and most recently, even haploid ES cells capable of producing Holly, a semi-cloned fertile female medaka from a mosaic oocyte created by microinjecting a haploid ES cell nucleus directly into a normal oocyte. These breakthroughs make medaka a favoring vertebrate model for stem cell research, the topic of this review.
KeywordMedaka Stem Cells Pluripotency Chimera Nuclear Transplant Semi-cloning
Department[Yi MeiSheng; Hong Ni; Li ZhenDong; Yan Yan; Wang DanKe; Zhao HaoBin; Hong YunHan] Natl Univ Singapore, Dept Biol Sci, Singapore 119260, Singapore; [Yan Yan] Nanyang Technol Univ, Sch Chem & Biomed Engn, Div Bioengn, Singapore 637457, Singapore; [Zhao HaoBin] Huazhong Normal Univ, Sch Life Sci, Hubei Key Lab Genet Regulat & Integrat Biol, Wuhan 430079, Peoples R China; [Hong YunHan] Chinese Acad Sci, Inst Hydrobiol, State Key Lab Freshwater Ecol & Biotechnol, Wuhan 430072, Peoples R China
Subject AreaBiology
Funding OrganizationBiomedical Research Council of Singapore [05-1-21-19-404, R-08-1-21-19-585, SBIC-SSCC-002-2007]; Ministry of Education of Singapore [R-154-000-285-112]; National University of Singapore [R-154-000-153-720] ; Biomedical Research Council of Singapore [05-1-21-19-404, R-08-1-21-19-585, SBIC-SSCC-002-2007]; Ministry of Education of Singapore [R-154-000-285-112]; National University of Singapore [R-154-000-153-720] ; Biomedical Research Council of Singapore [05-1-21-19-404, R-08-1-21-19-585, SBIC-SSCC-002-2007]; Ministry of Education of Singapore [R-154-000-285-112]; National University of Singapore [R-154-000-153-720] ; Biomedical Research Council of Singapore [05-1-21-19-404, R-08-1-21-19-585, SBIC-SSCC-002-2007]; Ministry of Education of Singapore [R-154-000-285-112]; National University of Singapore [R-154-000-153-720]
Indexed BySCI
WOS IDWOS:000277417800005
Funding OrganizationBiomedical Research Council of Singapore [05-1-21-19-404, R-08-1-21-19-585, SBIC-SSCC-002-2007]; Ministry of Education of Singapore [R-154-000-285-112]; National University of Singapore [R-154-000-153-720] ; Biomedical Research Council of Singapore [05-1-21-19-404, R-08-1-21-19-585, SBIC-SSCC-002-2007]; Ministry of Education of Singapore [R-154-000-285-112]; National University of Singapore [R-154-000-153-720] ; Biomedical Research Council of Singapore [05-1-21-19-404, R-08-1-21-19-585, SBIC-SSCC-002-2007]; Ministry of Education of Singapore [R-154-000-285-112]; National University of Singapore [R-154-000-153-720] ; Biomedical Research Council of Singapore [05-1-21-19-404, R-08-1-21-19-585, SBIC-SSCC-002-2007]; Ministry of Education of Singapore [R-154-000-285-112]; National University of Singapore [R-154-000-153-720]
Citation statistics
Cited Times:13[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.ihb.ac.cn/handle/342005/13856
Collection鱼类生物学及渔业生物技术研究中心_期刊论文
Corresponding AuthorHong, YH, Natl Univ Singapore, Dept Biol Sci, 10 Kent Ridge Crescent, Singapore 119260, Singapore
Recommended Citation
GB/T 7714
Yi MeiSheng,Hong Ni,Li ZhenDong,et al. Medaka fish stem cells and their applications[J]. SCIENCE CHINA-LIFE SCIENCES,2010,53(4):426-434.
APA Yi MeiSheng.,Hong Ni.,Li ZhenDong.,Yan Yan.,Wang DanKe.,...&Hong, YH, Natl Univ Singapore, Dept Biol Sci, 10 Kent Ridge Crescent, Singapore 119260, Singapore.(2010).Medaka fish stem cells and their applications.SCIENCE CHINA-LIFE SCIENCES,53(4),426-434.
MLA Yi MeiSheng,et al."Medaka fish stem cells and their applications".SCIENCE CHINA-LIFE SCIENCES 53.4(2010):426-434.
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