中国科学院水生生物研究所机构知识库
Advanced  
IHB OpenIR  > 鱼类生物学及渔业生物技术研究中心  > 期刊论文
学科主题: Infectious Diseases; Parasitology; Tropical Medicine
题名: Distinct Genetic Diversity of Oncomelania hupensis, Intermediate Host of Schistosoma japonicum in Mainland China as Revealed by ITS Sequences
作者: Zhao, Qin Ping1, 2; Sen Jiang, Ming1; Littlewood, D. Timothy J.3; Nie, Pin2
通讯作者: Zhao, QP, Wuhan Univ, Dept Parasitol, Sch Basic Med Sci, Wuhan 430072, Hubei Province, Peoples R China
关键词: FRAGMENT LENGTH POLYMORPHISMS ; MOLECULAR PHYLOGENY ; POPULATION-STRUCTURE ; DNA POLYMORPHISM ; GASTROPODA ; POMATIOPSIDAE ; RISSOOIDEA ; SNAIL ; BIOGEOGRAPHY ; COEVOLUTION
刊名: PLOS NEGLECTED TROPICAL DISEASES
发表日期: 2010-03-01
DOI: 10.1371/journal.pntd.0000611
卷: 4, 期:3, 页:-
收录类别: SCI
文章类型: Article
部门归属: [Zhao, Qin Ping; Sen Jiang, Ming] Wuhan Univ, Dept Parasitol, Sch Basic Med Sci, Wuhan 430072, Hubei Province, Peoples R China; [Zhao, Qin Ping; Nie, Pin] Chinese Acad Sci, State Key Lab Freshwater Ecol & Biotechnol, Inst Hydrobiol, Wuhan, Hubei Province, Peoples R China; [Littlewood, D. Timothy J.] Nat Hist Museum, Dept Zool, London SW7 5BD, England
WOS标题词: Science & Technology ; Life Sciences & Biomedicine
资助者: Chinese Academy of Sciences [KSCX2-YW-N-055, KSCX2-YW-2-0808]; National Natural Science Foundation of China [30770353]
类目[WOS]: Infectious Diseases ; Parasitology ; Tropical Medicine
研究领域[WOS]: Infectious Diseases ; Parasitology ; Tropical Medicine
摘要: Background: Oncomelania hupensis is the unique intermediate host of Schistosoma japonicum, which causes schistosomiasis endemic in the Far East, and especially in mainland China. O. hupensis largely determines the parasite's geographical range. How O. hupensis's genetic diversity is distributed geographically in mainland China has never been well examined with DNA sequence data. Methodology/Principal Findings: In this study we investigate the genetic variation among O. hupensis from different geographical origins using the combined complete internal transcribed spacer 1 (ITS1) and ITS2 regions of nuclear ribosomal DNA. 165 O. hupensis isolates were obtained in 29 localities from 7 provinces across mainland China: lake/marshland and hill regions in Anhui, Hubei, Hunan, Jiangxi and Jiangsu provinces, located along the middle and lower reaches of Yangtze River, and mountainous regions in Sichuan and Yunnan provinces. Phylogenetic and haplotype network analyses showed distinct genetic diversity and no shared haplotypes between populations from lake/marshland regions of the middle and lower reaches of the Yangtze River and populations from mountainous regions of Sichuan and Yunnan provinces. The genetic distance between these two groups is up to 0.81 based on Fst, and branch time was estimated as 26 Ma. As revealed in the phylogenetic tree, snails from Sichuan and Yunnan provinces were also clustered separately. Geographical separation appears to be an important factor accounting for the diversification of the two groups of O. hupensis in mainland China, and probably for the separate clades between snails from Sichuan and Yunnan provinces. In lake/marshland and hill regions along the middle and lower reaches of the Yangtze River, three clades were identified in the phylogenetic tree, but without any obvious clustering of snails from different provinces. Conclusions: O. hupensis in mainland China may have considerable genetic diversity, and a more complex population structure than expected. It will be of significant importance to consider the genetic diversity of O. hupensis when assessing co-evolutionary interactions with S. japonicum.
英文摘要: Background: Oncomelania hupensis is the unique intermediate host of Schistosoma japonicum, which causes schistosomiasis endemic in the Far East, and especially in mainland China. O. hupensis largely determines the parasite's geographical range. How O. hupensis's genetic diversity is distributed geographically in mainland China has never been well examined with DNA sequence data.
关键词[WOS]: FRAGMENT LENGTH POLYMORPHISMS ; MOLECULAR PHYLOGENY ; POPULATION-STRUCTURE ; DNA POLYMORPHISM ; GASTROPODA ; POMATIOPSIDAE ; RISSOOIDEA ; SNAIL ; BIOGEOGRAPHY ; COEVOLUTION
语种: 英语
WOS记录号: WOS:000276312200028
ISSN号: 1935-2735
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.ihb.ac.cn/handle/342005/13639
Appears in Collections:鱼类生物学及渔业生物技术研究中心_期刊论文

Files in This Item: Download All
File Name/ File Size Content Type Version Access License
Distinct Genetic Diversity of Oncomelania hupensis, Intermediate Host of Schistosoma japonicum in Mainland China as Revealed by ITS Sequences.pdf(534KB)----开放获取--View Download

作者单位: 1.Wuhan Univ, Dept Parasitol, Sch Basic Med Sci, Wuhan 430072, Hubei Province, Peoples R China
2.Chinese Acad Sci, State Key Lab Freshwater Ecol & Biotechnol, Inst Hydrobiol, Wuhan, Hubei Province, Peoples R China
3.Nat Hist Museum, Dept Zool, London SW7 5BD, England

Recommended Citation:
Zhao, Qin Ping; Sen Jiang, Ming; Littlewood, D. Timothy J.; Nie, Pin.Distinct Genetic Diversity of Oncomelania hupensis, Intermediate Host of Schistosoma japonicum in Mainland China as Revealed by ITS Sequences,PLOS NEGLECTED TROPICAL DISEASES,2010,4(3):-
Service
Recommend this item
Sava as my favorate item
Show this item's statistics
Export Endnote File
Google Scholar
Similar articles in Google Scholar
[Zhao, Qin Ping]'s Articles
[Sen Jiang, Ming]'s Articles
[Littlewood, D. Timothy J.]'s Articles
CSDL cross search
Similar articles in CSDL Cross Search
[Zhao, Qin Ping]‘s Articles
[Sen Jiang, Ming]‘s Articles
[Littlewood, D. Timothy J.]‘s Articles
Related Copyright Policies
Null
Social Bookmarking
Add to CiteULike Add to Connotea Add to Del.icio.us Add to Digg Add to Reddit
文件名: Distinct Genetic Diversity of Oncomelania hupensis, Intermediate Host of Schistosoma japonicum in Mainland China as Revealed by ITS Sequences.pdf
格式: Adobe PDF
所有评论 (0)
暂无评论
 
评注功能仅针对注册用户开放,请您登录
您对该条目有什么异议,请填写以下表单,管理员会尽快联系您。
内 容:
Email:  *
单位:
验证码:   刷新
您在IR的使用过程中有什么好的想法或者建议可以反馈给我们。
标 题:
 *
内 容:
Email:  *
验证码:   刷新

Items in IR are protected by copyright, with all rights reserved, unless otherwise indicated.

 

 

Valid XHTML 1.0!
Copyright © 2007-2016  中国科学院水生生物研究所 - Feedback
Powered by CSpace