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学科主题: Environmental Sciences
题名: Endocrine effects of sublethal exposure to persistent organic pollutants (POPS) on silver carp (Hypophthalmichthys molitrix)
作者: Xu, Y ; Zhang, J ; Li, W ; Schramm, KW ; Kettrup, A
通讯作者: Xu, Y, Chinese Acad Sci, Inst Hydrobiol, State Key Lab Freshwater Ecol & Biotechnol, Wuhan 430072, Peoples R China
关键词: POPs ; EROD ; UDPGT ; retinoids ; thyroid hormone ; silver carp
刊名: ENVIRONMENTAL POLLUTION
发表日期: 2002
卷: 120, 期:3, 页:683-690
收录类别: SCI
部门归属: Chinese Acad Sci, Inst Hydrobiol, State Key Lab Freshwater Ecol & Biotechnol, Wuhan 430072, Peoples R China; GSF, Natl Res Ctr Environmm & Hlth, Inst Ecol Chem, D-85764 Neuherberg, Germany
摘要: Silver carp (Hypophthalmichthys molitrix) samples were collected from five selected sites that represent diverse levels of downgraded persistent organic pollutants (POPs) contamination in Ya-Er Lake in October 1999. Hepatic ethoxyresorufin-O-deethylase (EROD) and UDP glucuronosyltransferase (UDPGT) activities, hepatosomatic index (HSI), hepatic retinoids, serum thyroid hormones were measured. It was found that hepatic retinol and serum free 3,5,3'- tetraiodothyronine (FT3) significantly increased (P < 0.01) when both hepatic EROD and UDPGT activities significantly declined (P < 0.01) from pond 1 to 5 with decrease in the degree of pollution. This significant negative correlation (P < 0.01) suggests that the persistent organochlorinated contaminants could induce hepatic EROD and UDPGT activities, alter retinoid and thyroid hormone homeostasis, and finally lead to the reduction of retinol and FT3, the two biologically active forms of retinoids and thyroid hormone in silver carp of Ya-Er Lake. (C) 2002 Elsevier Science Ltd. All rights reserved.
WOS记录号: WOS:000179013200020
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内容类型: 期刊论文
URI标识: http://ir.ihb.ac.cn/handle/152342/9780
Appears in Collections:中科院水生所知识产出(2009年前)_期刊论文

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Xu, Y; Zhang, J; Li, W; Schramm, KW; Kettrup, A.Endocrine effects of sublethal exposure to persistent organic pollutants (POPS) on silver carp (Hypophthalmichthys molitrix),ENVIRONMENTAL POLLUTION,2002,120(3):683-690
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