中国科学院水生生物研究所机构知识库
Advanced  
IHB OpenIR  > 中科院水生所知识产出(2009年前)  > 期刊论文
学科主题: Pharmacology & Pharmacy; Toxicology
题名: Microcystin-RR-induced apoptosis in tobacco BY-2 cells
作者: Yin, Liyan; Huang, Jiaquan; Li, Wei; Liu, Yongding
通讯作者: Liu, YD, Chinese Acad Sci, Inst Hydrobiol, Wuhan 430072, Peoples R China
关键词: microcystin-RR ; tobacco BY-2 cells ; apoptosis ; flow cytometry ; transmission electron microscopy
刊名: TOXICON
发表日期: 2006-08-01
DOI: 10.1016/j.toxicon.2006.05.002
卷: 48, 期:2, 页:204-210
收录类别: SCI
文章类型: Article
部门归属: Chinese Acad Sci, Inst Hydrobiol, Wuhan 430072, Peoples R China; Chinese Acad Sci, Bot Gardens, Wuhan 430072, Peoples R China; Chinese Acad Agr Sci, Oil Crops Res Inst, Wuhan 430062, Peoples R China
WOS标题词: Science & Technology ; Life Sciences & Biomedicine
类目[WOS]: Pharmacology & Pharmacy ; Toxicology
研究领域[WOS]: Pharmacology & Pharmacy ; Toxicology
摘要: Our previous studies showed that microcystin-RR could induce oxidative damage in plant cells as they do with animal cells. However, whether microcystin can induce plant cell apoptosis is still unknown. In this study, the morphological changes of tobacco BY-2 suspension cells exposed to microcystin-RR were observed under light microscopy and transmission electron microscopy, and apoptosis was clearly distinguished by intense perinuclear chromatin margination, condensation of nuclear chromatin after 6d exposure of 50 mg/L (about 50 mu M) microcystin-RR. We also found that microcystin-RR can induce tobacco cell apoptosis in a dose- and time-dependent manner with flow cytometry analysis. Our study provides the first evidence that microcystins can induce plant cell apoptosis. (c) 2006 Elsevier Ltd. All rights reserved.
英文摘要: Our previous studies showed that microcystin-RR could induce oxidative damage in plant cells as they do with animal cells. However, whether microcystin can induce plant cell apoptosis is still unknown. In this study, the morphological changes of tobacco BY-2 suspension cells exposed to microcystin-RR were observed under light microscopy and transmission electron microscopy, and apoptosis was clearly distinguished by intense perinuclear chromatin margination, condensation of nuclear chromatin after 6d exposure of 50 mg/L (about 50 mu M) microcystin-RR. We also found that microcystin-RR can induce tobacco cell apoptosis in a dose- and time-dependent manner with flow cytometry analysis. Our study provides the first evidence that microcystins can induce plant cell apoptosis. (c) 2006 Elsevier Ltd. All rights reserved.
关键词[WOS]: CYANOBACTERIAL TOXIN ; PROTEIN PHOSPHATASES ; LR ; INHIBITION ; HEPATOCYTES ; TOXICITY ; GROWTH ; PLANTS
语种: 英语
WOS记录号: WOS:000240050500008
ISSN号: 0041-0101
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.ihb.ac.cn/handle/152342/8856
Appears in Collections:中科院水生所知识产出(2009年前)_期刊论文

Files in This Item: Download All
File Name/ File Size Content Type Version Access License
Microcystin-RR-induced apoptosis in tobacco BY-2 cells.pdf(644KB)----开放获取--View Download

作者单位: 1.Chinese Acad Sci, Inst Hydrobiol, Wuhan 430072, Peoples R China
2.Chinese Acad Sci, Bot Gardens, Wuhan 430072, Peoples R China
3.Chinese Acad Agr Sci, Oil Crops Res Inst, Wuhan 430062, Peoples R China

Recommended Citation:
Yin, Liyan; Huang, Jiaquan; Li, Wei; Liu, Yongding.Microcystin-RR-induced apoptosis in tobacco BY-2 cells,TOXICON,2006,48(2):204-210
Service
Recommend this item
Sava as my favorate item
Show this item's statistics
Export Endnote File
Google Scholar
Similar articles in Google Scholar
[Yin, Liyan]'s Articles
[Huang, Jiaquan]'s Articles
[Li, Wei]'s Articles
CSDL cross search
Similar articles in CSDL Cross Search
[Yin, Liyan]‘s Articles
[Huang, Jiaquan]‘s Articles
[Li, Wei]‘s Articles
Related Copyright Policies
Null
Social Bookmarking
Add to CiteULike Add to Connotea Add to Del.icio.us Add to Digg Add to Reddit
文件名: Microcystin-RR-induced apoptosis in tobacco BY-2 cells.pdf
格式: Adobe PDF
此文件暂不支持浏览
所有评论 (0)
暂无评论
 
评注功能仅针对注册用户开放,请您登录
您对该条目有什么异议,请填写以下表单,管理员会尽快联系您。
内 容:
Email:  *
单位:
验证码:   刷新
您在IR的使用过程中有什么好的想法或者建议可以反馈给我们。
标 题:
 *
内 容:
Email:  *
验证码:   刷新

Items in IR are protected by copyright, with all rights reserved, unless otherwise indicated.

 

 

Valid XHTML 1.0!
Copyright © 2007-2016  中国科学院水生生物研究所 - Feedback
Powered by CSpace