Microcalorimetric study on the toxic effect of Pb2+ to Tetrahymena | |
Liu Peng; Zhang Weiying; Li Xi; Chen Xiaojuan; Zhang Chaocan; Liu, P, Wuhan Univ Technol, Sch Sci, Dept Appl Chem, Wuhan 430070, Peoples R China | |
2007-11-01 | |
Source Publication | BIOLOGICAL TRACE ELEMENT RESEARCH
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ISSN | 0163-4984 |
Volume | 119Issue:2Pages:175-182 |
Abstract | The toxic effect of Pb2+ has been studied in eukaryotic cells by using Tetrahymena as a target. The maximum power (P (m)) and the growth rate constant (k) were determined, which showed that values of P (m) and k were linked to the concentration (C) of Pb2+. The addition of Pb2+ caused a decrease of the maximum heat production and growth rate constant, indicating that Tetrahymena growth was inhibited in the presence of Pb2+, and Pb2+ took part in the metabolism of cells. From micrographs, morphological changes of Tetrahymena were observed with addition of Pb2+, indicating that the toxic effect of Pb2+ derived from destroying the membrane of surface of Tetrahymena. According to the thermogenic curves and photos of Tetrahymena under different conditions, it is clear that metabolic mechanism of Halobacterium halobium R1 growth has been changed with the addition of Pb2+.; The toxic effect of Pb2+ has been studied in eukaryotic cells by using Tetrahymena as a target. The maximum power (P (m)) and the growth rate constant (k) were determined, which showed that values of P (m) and k were linked to the concentration (C) of Pb2+. The addition of Pb2+ caused a decrease of the maximum heat production and growth rate constant, indicating that Tetrahymena growth was inhibited in the presence of Pb2+, and Pb2+ took part in the metabolism of cells. From micrographs, morphological changes of Tetrahymena were observed with addition of Pb2+, indicating that the toxic effect of Pb2+ derived from destroying the membrane of surface of Tetrahymena. According to the thermogenic curves and photos of Tetrahymena under different conditions, it is clear that metabolic mechanism of Halobacterium halobium R1 growth has been changed with the addition of Pb2+. |
Subtype | Article |
Keyword | Pb2++ Toxic Effect Tetrahymena Inhibitor Membrane |
Department | Wuhan Univ Technol, Sch Sci, Dept Appl Chem, Wuhan 430070, Peoples R China; Chinese Acad Sci, Inst Hydrobiol, Beijing, Peoples R China |
Subject Area | Biochemistry & Molecular Biology ; Endocrinology & Metabolism |
DOI | 10.1007/s12011-007-0055-3 |
WOS Headings | Science & Technology ; Life Sciences & Biomedicine |
Indexed By | SCI |
Language | 英语 |
WOS Research Area | Biochemistry & Molecular Biology ; Endocrinology & Metabolism |
WOS Subject | Biochemistry & Molecular Biology ; Endocrinology & Metabolism |
WOS ID | WOS:000249646000009 |
Citation statistics | |
Document Type | 期刊论文 |
Identifier | http://ir.ihb.ac.cn/handle/152342/8428 |
Collection | 期刊论文 |
Corresponding Author | Liu, P, Wuhan Univ Technol, Sch Sci, Dept Appl Chem, Wuhan 430070, Peoples R China |
Affiliation | 1.Wuhan Univ Technol, Sch Sci, Dept Appl Chem, Wuhan 430070, Peoples R China 2.Chinese Acad Sci, Inst Hydrobiol, Beijing, Peoples R China |
Recommended Citation GB/T 7714 | Liu Peng,Zhang Weiying,Li Xi,et al. Microcalorimetric study on the toxic effect of Pb2+ to Tetrahymena[J]. BIOLOGICAL TRACE ELEMENT RESEARCH,2007,119(2):175-182. |
APA | Liu Peng,Zhang Weiying,Li Xi,Chen Xiaojuan,Zhang Chaocan,&Liu, P, Wuhan Univ Technol, Sch Sci, Dept Appl Chem, Wuhan 430070, Peoples R China.(2007).Microcalorimetric study on the toxic effect of Pb2+ to Tetrahymena.BIOLOGICAL TRACE ELEMENT RESEARCH,119(2),175-182. |
MLA | Liu Peng,et al."Microcalorimetric study on the toxic effect of Pb2+ to Tetrahymena".BIOLOGICAL TRACE ELEMENT RESEARCH 119.2(2007):175-182. |
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