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学科主题: Integrative & Complementary Medicine; Medicine ; General & Internal
题名: Free radical scavenging and antioxidant enzymes activation of polysaccharide extract from Nostoc sphaeroides
作者: Tang, Jun; Hu, Zheng-Yu; Chen, Xin-Wen
通讯作者: Hu, ZY, Chinese Acad Sci, Inst Hydrobiol, State Key Lab Freshwater Ecol & Biotechnol, 7 South Donghu Rd,Wuchang Dist, Wuhan 430072, Hubei Province, Peoples R China
关键词: Nostoc sphaeroides kuetzing ; polysaccharide ; antioxidant activity ; scavenging effect ; lipid peroxidation ; human embryo kidney 293 cells
刊名: AMERICAN JOURNAL OF CHINESE MEDICINE
发表日期: 2007
卷: 35, 期:5, 页:887-896
收录类别: SCI
文章类型: Article
部门归属: Chinese Acad Sci, Inst Hydrobiol, State Key Lab Freshwater Ecol & Biotechnol, Wuhan 430072, Hubei Province, Peoples R China; Chinese Acad Sci, Grad Sch, Beijing 100049, Peoples R China; Chinese Acad Sci, Wuhan Inst Virol, State Key Lab Virol, Wuhan 430071, Peoples R China
WOS标题词: Science & Technology ; Life Sciences & Biomedicine
类目[WOS]: Integrative & Complementary Medicine ; Medicine, General & Internal
研究领域[WOS]: Integrative & Complementary Medicine ; General & Internal Medicine
摘要: Nostoc sphaeroides Kuetzing has been used as a traditional medicine in China to treat a variety of ailments. This research identified the antioxidant activities of polysaccharide extract from Nostoc sphaeroides. The extract, which contains 46.2% carbohydrates, exhibited an effective scavenging capability on superoxide radical, hydroxyl radicals in non site-specific as well as site-specific assays, and also performed lipid peroxidation inhibition in a dose-dependent manner. Polysaccharide extract had no 1,1-diphenyl-2-picrylhydrazyl radical scavenging potential at all test concentrations. Activities of superoxide dismutase, catalase, and glutathione peroxidase in human embryo kidney 293 cells were increased effectively when Nostoc sphaeroides extract was applied. These results suggested that the use of N. sphaeroides in treating ailments may be based on the antioxidant capacities of polysaccharide composition.
英文摘要: Nostoc sphaeroides Kuetzing has been used as a traditional medicine in China to treat a variety of ailments. This research identified the antioxidant activities of polysaccharide extract from Nostoc sphaeroides. The extract, which contains 46.2% carbohydrates, exhibited an effective scavenging capability on superoxide radical, hydroxyl radicals in non site-specific as well as site-specific assays, and also performed lipid peroxidation inhibition in a dose-dependent manner. Polysaccharide extract had no 1,1-diphenyl-2-picrylhydrazyl radical scavenging potential at all test concentrations. Activities of superoxide dismutase, catalase, and glutathione peroxidase in human embryo kidney 293 cells were increased effectively when Nostoc sphaeroides extract was applied. These results suggested that the use of N. sphaeroides in treating ailments may be based on the antioxidant capacities of polysaccharide composition.
关键词[WOS]: XIAN-MI NOSTOC ; EDIBLE CYANOBACTERIUM ; PLANT-EXTRACTS ; GROWTH ; OXYGEN
语种: 英语
WOS记录号: WOS:000250826600015
ISSN号: 0192-415X
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.ihb.ac.cn/handle/152342/8368
Appears in Collections:中科院水生所知识产出(2009年前)_期刊论文

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作者单位: 1.Chinese Acad Sci, Inst Hydrobiol, State Key Lab Freshwater Ecol & Biotechnol, Wuhan 430072, Hubei Province, Peoples R China
2.Chinese Acad Sci, Grad Sch, Beijing 100049, Peoples R China
3.Chinese Acad Sci, Wuhan Inst Virol, State Key Lab Virol, Wuhan 430071, Peoples R China

Recommended Citation:
Tang, Jun; Hu, Zheng-Yu; Chen, Xin-Wen.Free radical scavenging and antioxidant enzymes activation of polysaccharide extract from Nostoc sphaeroides,AMERICAN JOURNAL OF CHINESE MEDICINE,2007,35(5):887-896
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