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Plasma biochemical responses of the omnivorous crucian carp (Carassius auratus) to crude cyanobacterial extracts
Zhang, Xuezhen1; Xie, Ping1,2; Wang, Weimin1; Li, Dapeng1,2; Shi, Zechao3; Xie, P, Huazhong Agr Univ, Coll Fisheries, Minist Educ, Key Lab Agr Anim Genet Breeding & Reprod, Wuhan 430070, Peoples R China
2008-12-01
Source PublicationFISH PHYSIOLOGY AND BIOCHEMISTRY
ISSN0920-1742
Volume34Issue:4Pages:323-329
AbstractHealthy crucian carp (Carassius auratus) were treated by intraperitoneal (i.p.) injection of crude cyanobacterial extracts at two doses, 50 and 200 mu g MC-LR equiv kg(-1) BW. High mortality (100%) was observed within 60 h post injection in the high-dose group. In the treated fish, activities of four plasma enzymes, alanine aminotransferase (ALT), alkaline phosphatase (ALP), aspartate aminotransferase (AST), and lactate dehydrogenase (LDH), all showed substantial increases, with both dose and time-dependent effects. These increases of enzyme activity indicate severe impairment occurred in the liver of crucian carp over time. Plasma concentrations of energy-related biomolecules including glucose (GLU), cholesterol (CHO), triglyceride (TG), and total protein (TP) showed marked changes in the high-dose group, possibly a nutritional imbalance correlated with the liver injury caused by intraperitoneal exposure to crude cyanobacterial extracts.; Healthy crucian carp (Carassius auratus) were treated by intraperitoneal (i.p.) injection of crude cyanobacterial extracts at two doses, 50 and 200 mu g MC-LR equiv kg(-1) BW. High mortality (100%) was observed within 60 h post injection in the high-dose group. In the treated fish, activities of four plasma enzymes, alanine aminotransferase (ALT), alkaline phosphatase (ALP), aspartate aminotransferase (AST), and lactate dehydrogenase (LDH), all showed substantial increases, with both dose and time-dependent effects. These increases of enzyme activity indicate severe impairment occurred in the liver of crucian carp over time. Plasma concentrations of energy-related biomolecules including glucose (GLU), cholesterol (CHO), triglyceride (TG), and total protein (TP) showed marked changes in the high-dose group, possibly a nutritional imbalance correlated with the liver injury caused by intraperitoneal exposure to crude cyanobacterial extracts.
SubtypeArticle
KeywordCarassius Auratus Cyanobacterial Extracts Plasma Biochemistry
Department[Zhang, Xuezhen; Xie, Ping; Wang, Weimin; Li, Dapeng] Huazhong Agr Univ, Coll Fisheries, Minist Educ, Key Lab Agr Anim Genet Breeding & Reprod, Wuhan 430070, Peoples R China; [Xie, Ping; Li, Dapeng] Chinese Acad Sci, Inst Hydrobiol, State Key Lab Freshwater Ecol & Biotechnol China, Donghu Expt Stn Lake Ecosyst, Wuhan 430070, Peoples R China; [Shi, Zechao] Chinese Acad Fishery Sci, Yangtze River Fisheries Res Inst, Jinzhou 434000, Peoples R China
Subject AreaBiochemistry & Molecular Biology ; Fisheries ; Physiology
DOI10.1007/s10695-007-9191-0
WOS HeadingsScience & Technology ; Life Sciences & Biomedicine
Funding OrganizationHuazhong Agricultural University ; National Natural Science Foundation of China [30530170] ; Huazhong Agricultural University ; National Natural Science Foundation of China [30530170] ; Huazhong Agricultural University ; National Natural Science Foundation of China [30530170] ; Huazhong Agricultural University ; National Natural Science Foundation of China [30530170]
Indexed BySCI
Language英语
WOS Research AreaBiochemistry & Molecular Biology ; Fisheries ; Physiology
WOS SubjectBiochemistry & Molecular Biology ; Fisheries ; Physiology
WOS IDWOS:000260512800004
WOS KeywordCYCLIC PEPTIDE TOXIN ; MICROCYSTIN-LR ; CYPRINUS-CARPIO ; ONCORHYNCHUS-MYKISS ; RAINBOW-TROUT ; DANIO-RERIO ; SILVER CARP ; FISH ; TOXICITY ; ACCUMULATION
Funding OrganizationHuazhong Agricultural University ; National Natural Science Foundation of China [30530170] ; Huazhong Agricultural University ; National Natural Science Foundation of China [30530170] ; Huazhong Agricultural University ; National Natural Science Foundation of China [30530170] ; Huazhong Agricultural University ; National Natural Science Foundation of China [30530170]
Citation statistics
Document Type期刊论文
Identifierhttp://ir.ihb.ac.cn/handle/152342/7966
Collection期刊论文
Corresponding AuthorXie, P, Huazhong Agr Univ, Coll Fisheries, Minist Educ, Key Lab Agr Anim Genet Breeding & Reprod, Wuhan 430070, Peoples R China
Affiliation1.Huazhong Agr Univ, Coll Fisheries, Minist Educ, Key Lab Agr Anim Genet Breeding & Reprod, Wuhan 430070, Peoples R China
2.Chinese Acad Sci, Inst Hydrobiol, State Key Lab Freshwater Ecol & Biotechnol China, Donghu Expt Stn Lake Ecosyst, Wuhan 430070, Peoples R China
3.Chinese Acad Fishery Sci, Yangtze River Fisheries Res Inst, Jinzhou 434000, Peoples R China
Recommended Citation
GB/T 7714
Zhang, Xuezhen,Xie, Ping,Wang, Weimin,et al. Plasma biochemical responses of the omnivorous crucian carp (Carassius auratus) to crude cyanobacterial extracts[J]. FISH PHYSIOLOGY AND BIOCHEMISTRY,2008,34(4):323-329.
APA Zhang, Xuezhen,Xie, Ping,Wang, Weimin,Li, Dapeng,Shi, Zechao,&Xie, P, Huazhong Agr Univ, Coll Fisheries, Minist Educ, Key Lab Agr Anim Genet Breeding & Reprod, Wuhan 430070, Peoples R China.(2008).Plasma biochemical responses of the omnivorous crucian carp (Carassius auratus) to crude cyanobacterial extracts.FISH PHYSIOLOGY AND BIOCHEMISTRY,34(4),323-329.
MLA Zhang, Xuezhen,et al."Plasma biochemical responses of the omnivorous crucian carp (Carassius auratus) to crude cyanobacterial extracts".FISH PHYSIOLOGY AND BIOCHEMISTRY 34.4(2008):323-329.
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