| Plasma biochemical responses of the omnivorous crucian carp (Carassius auratus) to crude cyanobacterial extracts | |
| Zhang, Xuezhen1; Xie, Ping1,2; Wang, Weimin1; Li, Dapeng1,2; Shi, Zechao3; Xie, P, Huazhong Agr Univ, Coll Fisheries, Minist Educ, Key Lab Agr Anim Genet Breeding & Reprod, Wuhan 430070, Peoples R China | |
| 2008-12-01 | |
| Source Publication | FISH PHYSIOLOGY AND BIOCHEMISTRY
 |
| ISSN | 0920-1742 |
| Volume | 34Issue:4Pages:323-329 |
| Abstract | Healthy crucian carp (Carassius auratus) were treated by intraperitoneal (i.p.) injection of crude cyanobacterial extracts at two doses, 50 and 200 mu g MC-LR equiv kg(-1) BW. High mortality (100%) was observed within 60 h post injection in the high-dose group. In the treated fish, activities of four plasma enzymes, alanine aminotransferase (ALT), alkaline phosphatase (ALP), aspartate aminotransferase (AST), and lactate dehydrogenase (LDH), all showed substantial increases, with both dose and time-dependent effects. These increases of enzyme activity indicate severe impairment occurred in the liver of crucian carp over time. Plasma concentrations of energy-related biomolecules including glucose (GLU), cholesterol (CHO), triglyceride (TG), and total protein (TP) showed marked changes in the high-dose group, possibly a nutritional imbalance correlated with the liver injury caused by intraperitoneal exposure to crude cyanobacterial extracts.; Healthy crucian carp (Carassius auratus) were treated by intraperitoneal (i.p.) injection of crude cyanobacterial extracts at two doses, 50 and 200 mu g MC-LR equiv kg(-1) BW. High mortality (100%) was observed within 60 h post injection in the high-dose group. In the treated fish, activities of four plasma enzymes, alanine aminotransferase (ALT), alkaline phosphatase (ALP), aspartate aminotransferase (AST), and lactate dehydrogenase (LDH), all showed substantial increases, with both dose and time-dependent effects. These increases of enzyme activity indicate severe impairment occurred in the liver of crucian carp over time. Plasma concentrations of energy-related biomolecules including glucose (GLU), cholesterol (CHO), triglyceride (TG), and total protein (TP) showed marked changes in the high-dose group, possibly a nutritional imbalance correlated with the liver injury caused by intraperitoneal exposure to crude cyanobacterial extracts. |
| Subtype | Article |
| Keyword | Carassius Auratus Cyanobacterial Extracts Plasma Biochemistry |
| Department | [Zhang, Xuezhen; Xie, Ping; Wang, Weimin; Li, Dapeng] Huazhong Agr Univ, Coll Fisheries, Minist Educ, Key Lab Agr Anim Genet Breeding & Reprod, Wuhan 430070, Peoples R China; [Xie, Ping; Li, Dapeng] Chinese Acad Sci, Inst Hydrobiol, State Key Lab Freshwater Ecol & Biotechnol China, Donghu Expt Stn Lake Ecosyst, Wuhan 430070, Peoples R China; [Shi, Zechao] Chinese Acad Fishery Sci, Yangtze River Fisheries Res Inst, Jinzhou 434000, Peoples R China |
| Subject Area | Biochemistry & Molecular Biology ; Fisheries ; Physiology |
| DOI | 10.1007/s10695-007-9191-0 |
| WOS Headings | Science & Technology ; Life Sciences & Biomedicine |
| Funding Organization | Huazhong Agricultural University ; National Natural Science Foundation of China [30530170] ; Huazhong Agricultural University ; National Natural Science Foundation of China [30530170] ; Huazhong Agricultural University ; National Natural Science Foundation of China [30530170] ; Huazhong Agricultural University ; National Natural Science Foundation of China [30530170] |
| Indexed By | SCI |
| Language | 英语 |
| WOS Research Area | Biochemistry & Molecular Biology ; Fisheries ; Physiology |
| WOS Subject | Biochemistry & Molecular Biology ; Fisheries ; Physiology |
| WOS ID | WOS:000260512800004 |
| WOS Keyword | CYCLIC PEPTIDE TOXIN ; MICROCYSTIN-LR ; CYPRINUS-CARPIO ; ONCORHYNCHUS-MYKISS ; RAINBOW-TROUT ; DANIO-RERIO ; SILVER CARP ; FISH ; TOXICITY ; ACCUMULATION |
| Funding Organization | Huazhong Agricultural University ; National Natural Science Foundation of China [30530170] ; Huazhong Agricultural University ; National Natural Science Foundation of China [30530170] ; Huazhong Agricultural University ; National Natural Science Foundation of China [30530170] ; Huazhong Agricultural University ; National Natural Science Foundation of China [30530170] |
| Citation statistics | |
| Document Type | 期刊论文 |
| Identifier | http://ir.ihb.ac.cn/handle/152342/7966 |
| Collection | 期刊论文 |
| Corresponding Author | Xie, P, Huazhong Agr Univ, Coll Fisheries, Minist Educ, Key Lab Agr Anim Genet Breeding & Reprod, Wuhan 430070, Peoples R China |
| Affiliation | 1.Huazhong Agr Univ, Coll Fisheries, Minist Educ, Key Lab Agr Anim Genet Breeding & Reprod, Wuhan 430070, Peoples R China 2.Chinese Acad Sci, Inst Hydrobiol, State Key Lab Freshwater Ecol & Biotechnol China, Donghu Expt Stn Lake Ecosyst, Wuhan 430070, Peoples R China 3.Chinese Acad Fishery Sci, Yangtze River Fisheries Res Inst, Jinzhou 434000, Peoples R China |
| Recommended Citation GB/T 7714 | Zhang, Xuezhen,Xie, Ping,Wang, Weimin,et al. Plasma biochemical responses of the omnivorous crucian carp (Carassius auratus) to crude cyanobacterial extracts[J]. FISH PHYSIOLOGY AND BIOCHEMISTRY,2008,34(4):323-329. |
| APA | Zhang, Xuezhen,Xie, Ping,Wang, Weimin,Li, Dapeng,Shi, Zechao,&Xie, P, Huazhong Agr Univ, Coll Fisheries, Minist Educ, Key Lab Agr Anim Genet Breeding & Reprod, Wuhan 430070, Peoples R China.(2008).Plasma biochemical responses of the omnivorous crucian carp (Carassius auratus) to crude cyanobacterial extracts.FISH PHYSIOLOGY AND BIOCHEMISTRY,34(4),323-329. |
| MLA | Zhang, Xuezhen,et al."Plasma biochemical responses of the omnivorous crucian carp (Carassius auratus) to crude cyanobacterial extracts".FISH PHYSIOLOGY AND BIOCHEMISTRY 34.4(2008):323-329. |
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