IHB OpenIR  > 期刊论文
HORMONAL REPLACEMENT THERAPY IN FISH - HUMAN GROWTH-HORMONE GENE-FUNCTION IN HYPOPHYSECTOMIZED CARP
Zongbin Cui; Zuoyan Zhu
1993
Source PublicationFISH PHYSIOLOGY AND BIOCHEMISTRY
Volume12Issue:2Pages:161-169
AbstractTransgenic common carp, Cyprinus carpio, produced by the microinjection of fertilized eggs with a linearized chimeric plasmid pMThGH, a human growth hormone (hGH) gene with a mouse metallothionein-I (MT) gene promoter in pBR322, were used to produce F1 and F2 transgenics. Following hypophysectomy of the transgenic F2 common carp, non-transgenic common carp and non-transgenic crucian carp, growth was monitored for up to 110 days. In addition, recombinant hGH was injected subcutaenously into a group of the non-transgenic crucian carp. Growth rate analyses indicated that (1) hypophysectomy of non-transgenic common carp and crucian carp results in the cessation of growth, (2) hGH administration can stimulate the growth of hypophysectomized crucian carp and (3) hypophysectomized hGH-transgenic common carp continue to grow in the absence of their own growth hormone, suggesting that the hGH-transgene is being expressed in tissues other than the pituitary.
KeywordCommon Carp Crucian Carp Growth Hormone Growth Hormone Gene Transgenic Fish Hormonal Replacement Hypophysectomy
DepartmentUNIV ABERDEEN,DEPT MOLEC & CELL BIOL,ABERDEEN AB9 2TN,SCOTLAND; CHINESE ACAD SCI,INST HYDROBIOL,WUHAN,HUBEI 430072,PEOPLES R CHINA; UNIV ABERDEEN,DEPT ZOOL,ABERDEEN AB9 2TN,SCOTLAND
Subject AreaBiochemistry & Molecular Biology ; Fisheries ; Physiology
Indexed BySCI
WOS IDWOS:A1993LZ11300009
Citation statistics
Cited Times:2[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.ihb.ac.cn/handle/152342/10324
Collection期刊论文
Recommended Citation
GB/T 7714
Zongbin Cui,Zuoyan Zhu. HORMONAL REPLACEMENT THERAPY IN FISH - HUMAN GROWTH-HORMONE GENE-FUNCTION IN HYPOPHYSECTOMIZED CARP[J]. FISH PHYSIOLOGY AND BIOCHEMISTRY,1993,12(2):161-169.
APA Zongbin Cui,&Zuoyan Zhu.(1993).HORMONAL REPLACEMENT THERAPY IN FISH - HUMAN GROWTH-HORMONE GENE-FUNCTION IN HYPOPHYSECTOMIZED CARP.FISH PHYSIOLOGY AND BIOCHEMISTRY,12(2),161-169.
MLA Zongbin Cui,et al."HORMONAL REPLACEMENT THERAPY IN FISH - HUMAN GROWTH-HORMONE GENE-FUNCTION IN HYPOPHYSECTOMIZED CARP".FISH PHYSIOLOGY AND BIOCHEMISTRY 12.2(1993):161-169.
Files in This Item:
File Name/Size DocType Version Access License
HORMONAL REPLACEMENT(693KB) 开放获取--View Application Full Text
Related Services
Recommend this item
Bookmark
Usage statistics
Export to Endnote
Google Scholar
Similar articles in Google Scholar
[Zongbin Cui]'s Articles
[Zuoyan Zhu]'s Articles
Baidu academic
Similar articles in Baidu academic
[Zongbin Cui]'s Articles
[Zuoyan Zhu]'s Articles
Bing Scholar
Similar articles in Bing Scholar
[Zongbin Cui]'s Articles
[Zuoyan Zhu]'s Articles
Terms of Use
No data!
Social Bookmark/Share
File name: HORMONAL REPLACEMENT THERAPY IN FISH - HUMAN GROWTH-HORMONE GENE-FUNCTION IN HYPOPHYSECTOMIZED CARP.pdf
Format: Adobe PDF
This file does not support browsing at this time
All comments (0)
No comment.
 

Items in the repository are protected by copyright, with all rights reserved, unless otherwise indicated.