| Influence of dioxin and metal-contaminated sediment on phase I and II biotransformation enzymes in silver crucian carp | |
| Chen Guosheng; Xu Ying; Xu Lihong; Zhang Yongyuan; Karl-Werner Schramm and Antonius Kettrup; Chen, GS, Chinese Acad Sci, Inst Hydrobiol, State Key Lab Freshwater Ecol & Biotechnol, Wuhan 430072, Peoples R China | |
| 1998 | |
| Source Publication | ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
 |
| Volume | 40Issue:3Pages:234-238 |
| Abstract | Several biochemical responses were measured in silver crucian carp (Carassius auratus gibelio) after exposure to sediments obtained from contaminated Ya-Er Lake, No, 1 pond, and an unpolluted reference site, Honglian Lake. After 1 week of exposure, a significant induction of the phase I biotransformation enzyme (ethoxylresorufin-o-deethylase, EROD) was found (83-fold of control), whereas the phase II biotransformation enzyme (glutathione S-transferase, GST) exhibited a slight, but significant induction (1,4-fold of control) after 4 weeks of exposure. The level of cellular glutathione in the liver was also slightly elevated after 4 weeks of exposure. The delayed response of GST to the contaminants indicates that the phase I and phase II biotransformation enzymes are regulated differently in fish. The results suggest that EROD is a sensitive bioindicator to assess the toxicity of dioxin-contamined sediment in the laboratory, (C) 1998 Academic Press. |
| Keyword | Atlantic Croaker Tissues Rainbow-trout Oxidative Stress Channel Catfish Mill Effluents Glutathione Fish Transferase Induction Exposure |
| Department | Chinese Acad Sci, Inst Hydrobiol, State Key Lab Freshwater Ecol & Biotechnol, Wuhan 430072, Peoples R China; GSF Forschungszentrum Umwelt & Gesundheit, Inst Ecol Chem, D-85764 Neuherberg, Germany |
| Subject Area | Environmental Sciences ; Toxicology |
| Indexed By | SCI |
| Language | 英语 |
| WOS ID | WOS:000074901000008 |
| Citation statistics | |
| Document Type | 期刊论文 |
| Identifier | http://ir.ihb.ac.cn/handle/152342/10232 |
| Collection | 期刊论文 |
| Corresponding Author | Chen, GS, Chinese Acad Sci, Inst Hydrobiol, State Key Lab Freshwater Ecol & Biotechnol, Wuhan 430072, Peoples R China |
| Recommended Citation GB/T 7714 | Chen Guosheng,Xu Ying,Xu Lihong,et al. Influence of dioxin and metal-contaminated sediment on phase I and II biotransformation enzymes in silver crucian carp[J]. ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY,1998,40(3):234-238. |
| APA | Chen Guosheng,Xu Ying,Xu Lihong,Zhang Yongyuan,Karl-Werner Schramm and Antonius Kettrup,&Chen, GS, Chinese Acad Sci, Inst Hydrobiol, State Key Lab Freshwater Ecol & Biotechnol, Wuhan 430072, Peoples R China.(1998).Influence of dioxin and metal-contaminated sediment on phase I and II biotransformation enzymes in silver crucian carp.ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY,40(3),234-238. |
| MLA | Chen Guosheng,et al."Influence of dioxin and metal-contaminated sediment on phase I and II biotransformation enzymes in silver crucian carp".ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY 40.3(1998):234-238. |
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