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学科主题: Biochemistry & Molecular Biology; Biophysics
题名: Sequence of genome segments 1, 2, and 3 of the grass carp reovirus (Genus Aquareovirus, family Reoviridae)
作者: Qin Fang ; Houssam Attoui ; Jean Francois Philippe Biagini ; Zuoyan Zhu ; Philippe de Micco ; Xavier de Lamballerie
通讯作者: de Lamballerie, X, Univ Mediterranee, Fac Med Marseille, Lab Virol Mol Trop & Transfus, 27 Blvd Jean Moulin, F-13005 Marseille 5, France
关键词: aquareovirus ; GCRV ; GCHV ; grass carp ; double-stranded RNA ; polysegmented fish reoviruses
刊名: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
发表日期: 2000
卷: 274, 期:3, 页:762-766
收录类别: SCI
部门归属: Univ Mediterranee, Fac Med Marseille, Lab Virol Mol Trop & Transfus, F-13005 Marseille 5, France; EFS Alpes Mediterranee, Unite Virus Emergents, Mol Virol Lab, F-13005 Marseille, France; CAS, Wuhan Inst Virol, State Key Lab Freshwater Ecol & Biotechnol, Wuhan 430071, Peoples R China; CAS, Wuhan Inst Virol, Inst Hydrobiol, Wuhan 430071, Peoples R China
摘要: The genome segments 1, 2, and 3 of the grass carp reovirus (GCRV), a tentative species assigned to genus Aquareouirus, family Reouiridae, were sequenced. The respective segments 1, 2, and 3 were 3949, 3877, and 3702 nucleotides long. Conserved moths 5' (GUUAUUU) and 3' (UUCAUC) were found at the ends of each segment. Each segment contains a single ORF and the negative strand does not permit identification of consistent ORFs. Sequence analysis revealed that VP2 is the viral polymerase, while VPI might represent the viral guanyly/methyl transferase (involved in the capping process of RNA transcripts) and VP3 the NTPase/helicase (involved in the transcription and capping of viral RNAs), The highest amino acid identities (26-41%) were found with orthoreovirus proteins. Further genomic characterization should provide insight about the genetic relationships between GCRV, aquareoviruses, and orthoreoviruses, It should also permit to precise the taxonomic status of these different viruses. (C) 2000 Academic Press.
语种: 英语
WOS记录号: WOS:000088817800033
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.ihb.ac.cn/handle/152342/10104
Appears in Collections:中科院水生所知识产出(2009年前)_期刊论文

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.Sequence of genome segments 1, 2, and 3 of the grass carp reovirus (Genus Aquareovirus, family Reoviridae),BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS,2000,274(3):762-766
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